Assessing the essentiality of Leishmania donovani nitroreductase and its role in nitro drug activation (Q39233120)

10 September 2017

Assessing the essentiality of Leishmania donovani nitroreductase and its role in nitro drug activation (English)

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10 September 2017

Leishmania donovani

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3

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10 September 2017

Susan Wyllie

1

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author name string

Stephen Patterson

series ordinal

2

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10 September 2017

language of work or name

English

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publication date

3 December 2012

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Antimicrobial Agents and Chemotherapy

10 September 2017

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10 September 2017

57

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2

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10 September 2017

901-906

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describes a project that uses

10 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3553740/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population

1 reference

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The anti-trypanosome drug fexinidazole shows potential for treating visceral leishmaniasis

10 September 2017

1 reference

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High-throughput decoding of antitrypanosomal drug efficacy and resistance

10 September 2017

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Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness

10 September 2017

1 reference

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Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis

10 September 2017

1 reference

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Developments in the treatment of visceral leishmaniasis

10 September 2017

1 reference

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Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

Leishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

Energy converting NADH:quinone oxidoreductase (complex I).

10 September 2017

1 reference

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Royal Society of Tropical Medicine and Hygiene joint meeting with Médecins Sans Frontières at Manson House, London, 20 March 2003: field research in humanitarian medical programmes. Médecins Sans Frontières interventions against kala-azar in the Sud

10 September 2017

1 reference

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Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria

10 September 2017

1 reference

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The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice

10 September 2017

1 reference

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Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.

10 September 2017

1 reference

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Unresponsiveness to AmBisome in some Sudanese patients with kala-azar.

14 September 2017

1 reference

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The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553740

Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23208716

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.01788-12

1 reference

10 September 2017

1 reference

10 September 2017

PubMed publication ID

23208716

1 reference