Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection? (Q39220742)

http://europepmc.org/abstract/PMC/5977999

26 June 2018

title

Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection? (English)

1 reference

http://europepmc.org/abstract/PMC/5977999

26 June 2018

author

Rebecca Parodi-Rullan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Sabzali Javadov

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

Sehwan Jang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

Zaza Khuchua

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

Andrey V Kuznetsov

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

publication date

4 April 2017

1 reference

http://europepmc.org/abstract/PMC/5977999

26 June 2018

published in

Cellular and Molecular Life Sciences

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

volume

74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

2795-2813

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection

4 June 2020

cites work

1 reference

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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

30 June 2018

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Cyclophilin D regulates mitochondrial flashes and metabolism in cardiac myocytes

30 June 2018

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30 June 2018

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Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism

30 June 2018

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30 June 2018

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Cyclosporine before PCI in Patients with Acute Myocardial Infarction

30 June 2018

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Discovery, Synthesis, and Optimization of Diarylisoxazole-3-carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore.

30 June 2018

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30 June 2018

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Cyclosporine A reduces microvascular obstruction and preserves left ventricular function deterioration following myocardial ischemia and reperfusion.

30 June 2018

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The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARα-cyclophilin D interaction in cardiomyocytes

30 June 2018

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Sexual dimorphism in the expression of mitochondria-related genes in rat heart at different ages

30 June 2018

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GNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis

30 June 2018

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The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury.

30 June 2018

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Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore.

30 June 2018

1 reference

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Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective.

30 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotection

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

30 June 2018

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Physiological and structural differences in spatially distinct subpopulations of cardiac mitochondria: influence of cardiac pathologies

30 June 2018

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Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition

30 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux

30 June 2018

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Gemcitabine-induced pancreatic cancer cell death is associated with MST1/cyclophilin D mitochondrial complexation

30 June 2018

1 reference

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Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy

30 June 2018

1 reference

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Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

30 June 2018

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P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblasts

30 June 2018

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Chaperoning mitochondrial permeability transition: regulation of transition pore complex by a J-protein, DnaJC15.

30 June 2018

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The effect of cyclosporin-A on peri-operative myocardial injury in adult patients undergoing coronary artery bypass graft surgery: a randomised controlled clinical trial

30 June 2018

1 reference

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Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria

30 June 2018

1 reference

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Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening

30 June 2018

1 reference

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The mitochondria as a target for cardioprotection in acute myocardial ischemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin D modulates mitochondrial acetylome

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury.

30 June 2018

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Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F0-ATP synthase

30 June 2018

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Cisplatin-induced non-apoptotic death of pancreatic cancer cells requires mitochondrial cyclophilin-D-p53 signaling

30 June 2018

1 reference

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Dimers of mitochondrial ATP synthase form the permeability transition pore

30 June 2018

1 reference

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Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

30 June 2018

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Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axis

30 June 2018

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Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.

30 June 2018

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Myocardial ischemia-reperfusion injury: a neglected therapeutic target.

30 June 2018

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Methylation-controlled J-protein MCJ acts in the import of proteins into human mitochondria

30 June 2018

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CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism

30 June 2018

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Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

30 June 2018

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Mitochondria as a drug target in ischemic heart disease and cardiomyopathy

30 June 2018

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p53 opens the mitochondrial permeability transition pore to trigger necrosis

30 June 2018

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Direct renin inhibition exerts an anti-hypertrophic effect associated with improved mitochondrial function in post-infarction heart failure in diabetic rats.

30 June 2018

1 reference

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Regulation of ATP production by mitochondrial Ca(2 ).

30 June 2018

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Calcium-mediated cell death during myocardial reperfusion

30 June 2018

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Superoxide Flashes Reveal Novel Properties of Mitochondrial Reactive Oxygen Species Excitability in Cardiomyocytes

30 June 2018

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Induction of the permeability transition pore in cells depleted of mitochondrial DNA.

30 June 2018

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30 June 2018

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Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta‐analysis

30 June 2018

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Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

30 June 2018

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30 June 2018

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High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation

30 June 2018

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The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

30 June 2018

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Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals.

30 June 2018

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Targeting the Mitochondrial Permeability Transition: Cardiac Ischemia-Reperfusion <i>Versus</i> Carcinogenesis

30 June 2018

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Mitochondrial Ca2 influx and efflux rates in guinea pig cardiac mitochondria: low and high affinity effects of cyclosporine A

30 June 2018

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An Overview of Cyclophilins in Human Cancers

30 June 2018

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Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

30 June 2018

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Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

30 June 2018

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The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target Deprivation

30 June 2018

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Simultaneous Measurement of Protein Oxidation and S -Nitrosylation During Preconditioning and Ischemia/Reperfusion Injury With Resin-Assisted Capture

30 June 2018

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Ethanol sensitizes mitochondria to the permeability transition by inhibiting deacetylation of cyclophilin-D mediated by sirtuin-3

30 June 2018

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Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

30 June 2018

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Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

30 June 2018

1 reference

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Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death

30 June 2018

1 reference

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Cyclophilin D controls mitochondrial pore-dependent Ca(2 ) exchange, metabolic flexibility, and propensity for heart failure in mice

30 June 2018

1 reference

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The molecular identity of the mitochondrial Ca2 sequestration system

30 June 2018

1 reference

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Cardioprotective pathways during reperfusion: focus on redox signaling and other modalities of cell signaling.

30 June 2018

1 reference

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Cyclosporine A at reperfusion reduces infarct size in pigs

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Protein S-nitrosylation and cardioprotection

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

30 June 2018

1 reference

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Redox characterization of human cyclophilin D: identification of a new mammalian mitochondrial redox sensor?

30 June 2018

1 reference

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Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Why do we still not have cardioprotective drugs?

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mechanism for resveratrol-induced cardioprotection against reperfusion injury involves glycogen synthase kinase 3beta and mitochondrial permeability transition pore.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporine preserves mitochondrial morphology after myocardial ischemia/reperfusion independent of calcineurin inhibition

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Limitation of myocardial infarct size in the clinical setting: current status and challenges in translating animal experiments into clinical therapy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondria as a target for the cardioprotective effects of nitric oxide in ischemia-reperfusion injury

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Myocardial reperfusion injury.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

S-nitrosylation: NO-related redox signaling to protect against oxidative stress

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondrial subpopulations and heterogeneity revealed by confocal imaging: possible physiological role?

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Suppression of apoptosis by cyclophilin D via stabilization of hexokinase II mitochondrial binding in cancer cells.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Relationship between time of day, day of week, timeliness of reperfusion, and in-hospital mortality for patients with acute ST-segment elevation myocardial infarction

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2 signals by enhancing Ca2 uptake into the endoplasmic reticulum and mitochondria

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Identification of simian cyclophilin A as a calreticulin-binding protein in yeast two-hybrid screen and demonstration of cyclophilin A interaction with calreticulin

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporine A limits myocardial infarct size even when administered after onset of ischemia

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Peptidylproline cis-trans-isomerases: immunophilins

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Characterization of cysteine residues of mitochondrial ADP/ATP carrier with the SH-reagents eosin 5-maleimide and N-ethylmaleimide

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Heterogeneous response of subsarcolemmal heart mitochondria to calcium

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Inhibition of Ca2( )-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The effect of cyclosporine on electrically paced isolated rat cardiomyocytes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporin A inhibits an initial step in folding of transferrin within the endoplasmic reticulum

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mechanism of action of FK 506.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporin inhibits mitochondrial calcium efflux in isolated adult rat ventricular cardiomyocytes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporin A in patients receiving renal allografts from cadaver donors

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The Ca2 -induced membrane transition in mitochondria. II. Nature of the Ca2 trigger site

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Elucidating Mitochondrial Electron Transport Chain Supercomplexes in the Heart During Ischemia-Reperfusion

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Rationale and design of the Cyclosporine to ImpRove Clinical oUtcome in ST-elevation myocardial infarction patients (the CIRCUS trial).

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclophilin-D: a resident regulator of mitochondrial gene expression

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporine protects the heart during aortic valve surgery.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The effect of prethrombolytic cyclosporine-A injection on clinical outcome of acute anterior ST-elevation myocardial infarction

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

State of the science of cardioprotection: Challenges and opportunities--proceedings of the 2010 NHLBI Workshop on Cardioprotection

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Post-conditioning with cyclosporine A fails to reduce the infarct size in an in vivo porcine model

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Neonatal cardiac mitochondria and ischemia/reperfusion injury.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Effect of cyclosporine on reperfusion injury in acute myocardial infarction

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Fas-independent mitochondrial damage triggers cardiomyocyte death after ischemia-reperfusion

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Mitochondrial permeability transition pore as a target for cardioprotection in the human heart

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

NHE-1 inhibition improves impaired mitochondrial permeability transition and respiratory function during postinfarction remodelling in the rat.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Gender modulation of Ca(2 ) uptake in cardiac mitochondria

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Calcineurin-independent inhibition of mitochondrial Ca2 uptake by cyclosporin A.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Protection of myocardium by cyclosporin a and insulin: in vitro simulated ischemia study in human myocardium

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Temporary acidosis during reperfusion limits myocardial infarct size in dogs

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5977999

The mitochondrial permeability transition pore may comprise VDAC molecules

21 August 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-017-2502-4

The Ca2 -induced membrane transition in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-017-2502-4

Is p53 the Long-Sought Molecular Trigger for Cyclophilin D–Regulated Mitochondrial Permeability Transition Pore Formation and Necrosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-017-2502-4

Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2 and Oxidant Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-017-2502-4

Mitochondrial permeability transition in the diabetic heart: Contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury

21 January 2018

1 reference

12 December 2020

Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate

1 reference

12 December 2020

Action of cyclosporine on mitochondrial calcium fluxes

1 reference

12 December 2020

The beneficial effect of cyclosporine on liver ischemia in rats

1 reference

12 December 2020

NHE-1 inhibition improves cardiac mitochondrial function through regulation of mitochondrial biogenesis during postinfarction remodeling

1 reference

12 December 2020

Import and processing of heart mitochondrial cyclophilin D

1 reference

12 December 2020

Effect of cyclosporine A on ischemic renal failure in the rat

1 reference

12 December 2020

Regulation of mitochondrial metabolism through changes in matrix volume

1 reference

12 December 2020

Cyclosporine and the ischemic rat kidney

1 reference

12 December 2020

Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2

1 reference

12 December 2020

Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site

1 reference

12 December 2020

Structural organization of mitochondrial ATP synthase

1 reference

12 December 2020

Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice

1 reference

12 December 2020

Beneficial effect of cyclosporine pretreatment in preventing ischemic damage to the liver in dogs

1 reference

12 December 2020

Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A

1 reference

12 December 2020

10.1007/S00018-017-2502-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

release_k7lhhcs5sjfx3p65d4aiunnvw4

4 June 2020

Fatcat ID

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28378042 AND SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

28378042

1 reference