Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells. (Q39155162)

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29 February 2020

title

Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells (English)

1 reference

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29 February 2020

1 reference

3

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29 February 2020

author name string

Shulin Zhang

1

1 reference

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29 February 2020

Hao Long

2

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29 February 2020

Yucheng Wang

4

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29 February 2020

David Hsieh

5

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29 February 2020

Weiming Li

6

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29 February 2020

Alfred Au

7

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29 February 2020

Hubert J Stoppler

8

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29 February 2020

Zhidong Xu

9

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29 February 2020

David M Jablons

10

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29 February 2020

Liang You

11

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29 February 2020

publication date

8 May 2013

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Journal of Cellular and Molecular Medicine

29 February 2020

published in

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volume

17

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issue

7

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page(s)

854-862

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Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells

29 February 2020

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Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer

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Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.

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Discovery and SAR of 5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer

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Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.

10 September 2017

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Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

10 September 2017

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Protein kinase CK2 in health and disease: CK2 and its role in Wnt and NF-kappaB signaling: linking development and cancer.

10 September 2017

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Protein kinase CK2 in health and disease: CK2: a key player in cancer biology

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Protein kinase CK2--a key suppressor of apoptosis

10 September 2017

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Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

10 September 2017

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Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis

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Protein kinase CK2 subunits are positive regulators of AKT kinase

10 September 2017

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10 September 2017

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One-thousand-and-one substrates of protein kinase CK2?

10 September 2017

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Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality

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Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

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14 September 2017

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14 September 2017

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14 September 2017

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The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway

14 September 2017

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25 September 2017

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Overexpression of nuclear protein kinase CK2 Beta subunit and prognosis in human gastric carcinoma.

15 June 2018

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Multiple myeloma cell survival relies on high activity of protein kinase CK2.

21 August 2018

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Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

21 August 2018

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Nuclear matrix targeting of the protein kinase CK2 signal as a common downstream response to androgen or growth factor stimulation of prostate cancer cells

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23651443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear localization of protein kinase CK2 catalytic subunit (CK2alpha) is associated with poor prognostic factors in human prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23651443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/JCMM.12068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23651443 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23651443 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23651443

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23651443 AND SRC:MED&resulttype=core&format=json