New Target Sites for Treatment of Osteoporosis (Q39151180)

9 September 2017

title

New Target Sites for Treatment of Osteoporosis (English)

1 reference

9 September 2017

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1

Werner E G Müller

1 reference

9 September 2017

3

Heinz C Schröder

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9 September 2017

2

Xiaohong Wang

1 reference

9 September 2017

publication date

1 January 2017

1 reference

Progress in molecular and subcellular biology

9 September 2017

published in

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9 September 2017

volume

55

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9 September 2017

page(s)

187-219

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Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death

9 September 2017

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PPARγ signaling and metabolism: the good, the bad and the future

21 January 2018

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Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6

21 January 2018

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The effect of teriparatide on serum Dickkopf-1 levels in postmenopausal women with established osteoporosis.

21 January 2018

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Hypercalcemia Reduces Plasma Renin via Parathyroid Hormone, Renal Interstitial Calcium, and the Calcium-Sensing Receptor

21 January 2018

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Current and potential therapeutic targets of glucagon-like peptide-2.

21 January 2018

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The discovery of novel calcium sensing receptor negative allosteric modulators.

21 January 2018

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Ectopic secretion of osteocalcin, the major non-collagenous bone protein, by the myeloma cell line NCI-H929.

21 January 2018

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Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives

21 January 2018

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WNT signaling in bone homeostasis and disease: from human mutations to treatments

21 January 2018

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The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling

21 January 2018

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Role of dual-energy X-ray absorptiometry in the diagnosis and treatment of osteoporosis

21 January 2018

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Spotlight on teriparatide in osteoporosis.

21 January 2018

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The effect of three or six years of denosumab exposure in women with postmenopausal osteoporosis: results from the FREEDOM extension

21 January 2018

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Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro

21 January 2018

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The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases

21 January 2018

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Dietary phyto-oestrogens and bone health

21 January 2018

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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

21 January 2018

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Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches

21 January 2018

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The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro

21 January 2018

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Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo

21 January 2018

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https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor

21 January 2018

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https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

A review of osteocyte function and the emerging importance of sclerostin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Epidemiology and outcomes of osteoporotic fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Denosumab for prevention of fractures in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Lasofoxifene in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Transcription factor Runx2 and its application to bone tissue engineering.

21 January 2018

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https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Update on medications with adverse skeletal effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Potential new drug targets for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Treatment of bone diseases with bisphosphonates, excluding osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Flavonoids: old and new aspects of a class of natural therapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Toxicity and carcinogenicity studies of quercetin, a natural component of foods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Development of bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The physiology of the circadian rhythm of parathyroid hormone and its potential as a treatment for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Prevention and treatment of postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteoporosis and skeletal fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Biomarkers for osteoporosis management: utility in diagnosis, fracture risk prediction and therapy monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Sclerostin levels associated with inhibition of the Wnt/β-catenin signaling and reduced bone turnover in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Generation and Selection of Novel Fully Human Monoclonal Antibodies That Neutralize Dickkopf-1 (DKK1) Inhibitory Function in Vitro and Increase Bone Mass in Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

A Rate-Limiting Role for Dickkopf-1 in Bone Formation and the Remediation of Bone Loss in Mouse and Primate Models of Postmenopausal Osteoporosis by an Experimental Therapeutic Antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

An ancient Wnt-Dickkopf antagonism in Hydra

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: a randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH(2)] in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Estimating the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Expression of BMP-2 and Ets1 in BMP-2-stimulated mouse pre-osteoblast differentiation is regulated by microRNA-370.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

BMP2 protein regulates osteocalcin expression via Runx2-mediated Atf6 gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

ATF936, a novel oral calcilytic, increases bone mineral density in rats and transiently releases parathyroid hormone in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Level of catechin, myricetin, quercetin and isoquercitrin in buckwheat (Fagopyrum esculentum Moench), changes of their levels during vegetation and their effect on the growth of selected weeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Synopsis of a WHO report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Tanshinone IIA enhances BMP-2-stimulated commitment of C2C12 cells into osteoblasts via p38 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Bone regeneration is regulated by wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Wnt signaling in bone formation and its therapeutic potential for bone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inorganic polyphosphate: a molecule of many functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Positioning of Antioxidant Quercetin and Its Metabolites in Lipid Bilayer Membranes: Implication for Their Lipid-Peroxidation Inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Association between polymorphisms in Wnt signaling pathway genes and bone mineral density in postmenopausal Korean women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

RANK/RANKL: regulators of immune responses and bone physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Multiple Wnts are involved in Hydra organizer formation and regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Monoclonal antibodies for the treatment of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inorganic polyphosphate in human osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

New therapeutic targets for osteoporosis: beyond denosumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Mammalian intestinal alkaline phosphatase acts as highly active exopolyphosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Changes in metabolism of inorganic polyphosphate in rat tissues and human cells during development and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Systematic review: comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Extracellular modulators of Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Emerging therapies for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Src kinase activity is essential for osteoclast function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2 level in osteoblasts (SaOS-2 cells) in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Induction of carbonic anhydrase in SaOS-2 cells, exposed to bicarbonate and consequences for calcium phosphate crystal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Amorphous Ca²⁺ polyphosphate nanoparticles regulate the ATP level in bone-like SaOS-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Polyphosphate: A Morphogenetically Active Implant Material Serving as Metabolic Fuel for Bone Regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Mineralization of bone-related SaOS-2 cells under physiological hypoxic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The search for calcium receptor antagonists (calcilytics).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Calcimimetic and calcilytic drugs: just for parathyroid cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Strontium ranelate: the first agent of a new therapeutic class in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Bone remodeling in the context of cellular and systemic regulation: the role of osteocytes and the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The biological role of strontium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Dual Roles of Quercetin in Platelets: Phosphoinositide-3-Kinase and MAP Kinases Inhibition, and cAMP-Dependent Vasodilator-Stimulated Phosphoprotein Stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metallopr

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Relationships between polyphosphate chemistry, biochemistry and apatite biomineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Control of vertebrate skeletal mineralization by polyphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inorganic polyphosphate and energy metabolism in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Chronic administration of Glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Stimulatory effect of naturally occurring flavonols quercetin and kaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Pathogenesis of osteoporosis: concepts, conflicts, and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The position of strontium ranelate in today's management of osteoporosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Anti-resorptive therapies for osteoporosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Antagonizing the Calcium-Sensing Receptor: Towards New Bone Anabolics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The osteocyte as a therapeutic target in the treatment of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of strontium on human Runx2 /- osteoblasts from a patient with cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Bisphosphonates: pharmacology, mechanisms of action and clinical uses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

An Akt-dependent increase in canonical Wnt signaling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Assessment of Postmenopausal Women and Significant Risk Factors for Osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Flavone tetraglycosides and benzyl alcohol glycosides from the Mongolian medicinal plant Dracocephalum ruyschiana

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Denosumab for the Management of Postmenopausal Osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Quercetin, a bioflavonoid, accelerates TNF-alpha-induced growth inhibition and apoptosis in MC3T3-E1 osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double-blind, randomized, placebo-controlled phase I studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Differential diagnosis and secondary causes of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Recent updates on the calcium-sensing receptor as a drug target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

β-Arrestin-biased signaling of PTH analogs of the type 1 parathyroid hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

PPAR-gamma regulates osteoclastogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblast in primary osteoblast cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The marine sponge-derived inorganic polymers, biosilica and polyphosphate, as morphogenetically active matrices/scaffolds for the differentiation of human multipotent stromal cells: potential application in 3D printing and distraction osteogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Enzymatically synthesized inorganic polymers as morphogenetically active bone scaffolds: application in regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Isoquercitrin and polyphosphate co-enhance mineralization of human osteoblast-like SaOS-2 cells via separate activation of two RUNX2 cofactors AFT6 and Ets1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Modulation of the initial mineralization process of SaOS-2 cells by carbonic anhydrase activators and polyphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The morphogenetically active polymer, inorganic polyphosphate complexed with GdCl3, as an inducer of hydroxyapatite formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Polyphosphate as a metabolic fuel in Metazoa: A foundational breakthrough invention for biomedical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Regional and modular expression of morphogenetic factors in the demosponge Lubomirskia baicalensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteogenic potential of biosilica on human osteoblast-like (SaOS-2) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inorganic polyphosphate modulates TRPM8 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Odanacatib in postmenopausal women with low bone mineral density: a review of current clinical evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Dose-dependent effects of Runx2 on bone development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Bisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Four-month treatment with GLP-2 significantly increases hip BMD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

PPARβ/δ governs Wnt signaling and bone turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The effects of Dickkopf-1 antibody on metaphyseal bone and implant fixation under different loading conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteonecrosis of the jaw: what do bisphosphonates do?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Extracellular calcium sensing and extracellular calcium signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of age on calcium absorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The role of Dkk1 in bone mass regulation: Correlating serum Dkk1 expression with bone mineral density

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

A semimechanistic model of the time-course of release of PTH into plasma following administration of the calcilytic JTT-305/MK-5442 in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Pregnancy-associated osteoporosis with a heterozygous deactivating LDL receptor-related protein 5 (LRP5) mutation and a homozygous methylenetetrahydrofolate reductase (MTHFR) polymorphism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Dickkopf-1 is a master regulator of joint remodeling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of condensed phosphates on calcification of chick embryo femurs in tissue culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Acceleration of segmental bone regeneration in a rabbit model by strontium-doped calcium polyphosphate scaffold through stimulating VEGF and bFGF secretion from osteoblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Wnt signaling as a therapeutic target for bone diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Anabolic agents: a new chapter in the management of osteoporosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Epidemiology, etiology, and diagnosis of osteoporosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Odanacatib in the treatment of postmenopausal women with low bone mineral density: five years of continued therapy in a phase 2 study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

The menopause and osteoporosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Single- and Multiple-Dose Randomized Studies of Blosozumab, a Monoclonal Antibody Against Sclerostin, in Healthy Postmenopausal Women

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Silica as a morphogenetically active inorganic polymer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Fabrication of amorphous strontium polyphosphate microparticles that induce mineralization of bone cells in vitro and in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Effect of L-000845704, an alphaVbeta3 integrin antagonist, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Protective effects of gallium, germanium, and strontium against ovariectomized osteoporosis in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

Biosilica-based strategies for treatment of osteoporosis and other bone diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-51284-6_6

10.1007/978-3-319-51284-6_6

31 March 2020

Identifiers

DOI

1 reference

9 September 2017

1 reference