CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express Aurora kinase A. (Q39149922)

9 September 2017

title

CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express Aurora kinase A. (English)

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9 September 2017

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Jing Yang

1

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9 September 2017

Takayuki Ikezoe

2

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9 September 2017

Chie Nishioka

3

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9 September 2017

Atsuya Nobumoto

4

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9 September 2017

Keiko Udaka

5

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9 September 2017

Akihito Yokoyama

6

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9 September 2017

language of work or name

English

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publication date

10 June 2013

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International Journal of Cancer

9 September 2017

published in

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9 September 2017

volume

133

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9 September 2017

issue

11

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9 September 2017

page(s)

2706-2719

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

9 September 2017

cites work

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

21 January 2018

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Inhibition of signal transducer and activator of transcription 5 by the inhibitor of janus kinases stimulates dormant human leukemia CD34 /CD38− cells and sensitizes them to antileukemia agents

21 January 2018

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The cellular geography of aurora kinases

21 January 2018

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Aurora kinases as an anti-cancer target

21 January 2018

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Aurora-A - a guardian of poles

21 January 2018

1 reference

Aurora-A/STK15 T 91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types.

21 January 2018

1 reference

AURKA and BRCA2 expression highly correlate with prognosis of endometrioid ovarian carcinoma

21 January 2018

1 reference

Overexpression and amplification of Aurora-A in hepatocellular carcinoma

21 January 2018

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

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Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

21 January 2018

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

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Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells

21 January 2018

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Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia

21 January 2018

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Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

21 January 2018

1 reference

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

21 January 2018

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Aurora A selective inhibitor MLN8237 suppresses the growth and survival of HTLV-1-infected T-cells in vitro.

21 January 2018

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CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells

21 January 2018

1 reference

Insulin-like growth factor binding protein-3 antagonizes the effects of retinoids in myeloid leukemia cells

21 January 2018

1 reference

Self-Renewal of Leukemia Stem Cells in Friend Virus-Induced Erythroleukemia Requires Proviral Insertional Activation of Spi1 and Hedgehog Signaling but Not Mutation of p53

21 January 2018

1 reference

Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.

21 January 2018

1 reference

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

21 January 2018

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Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein

21 January 2018

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Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

21 January 2018

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p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells

21 January 2018

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML).

21 January 2018

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The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity

21 January 2018

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Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia.

21 January 2018

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Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

21 January 2018

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Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis

21 January 2018

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Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement

21 January 2018

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Aurora-A kinase: a novel target of cellular immunotherapy for leukemia

21 January 2018

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Analysis of Aurora B kinase in non-Hodgkin lymphoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.28277

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9 September 2017

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