Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region (Q39138307)

9 September 2017

title

Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region (English)

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9 September 2017

main subject

hepatocellular carcinoma

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Chuan Yin

1

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9 September 2017

Pei-Qin Wang

2

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9 September 2017

Wen-Ping Xu

3

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9 September 2017

Yuan Yang

4

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9 September 2017

Qing Zhang

5

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9 September 2017

Bei-Fang Ning

6

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9 September 2017

Ping-Ping Zhang

7

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9 September 2017

Wei-Ping Zhou

8

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9 September 2017

Wei-Fen Xie

9

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9 September 2017

Wan-Sheng Chen

10

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9 September 2017

Xin Zhang

11

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9 September 2017

language of work or name

English

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publication date

22 October 2013

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9 September 2017

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9 September 2017

volume

58

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9 September 2017

issue

6

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9 September 2017

page(s)

1964-1976

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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

9 September 2017

cites work

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Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

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The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

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Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene.

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Hepatocyte nuclear factor 4alpha attenuates hepatic fibrosis in rats

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Hepatocyte Nuclear Factor 4α Suppresses the Development of Hepatocellular Carcinoma

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An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis

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Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells

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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

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MicroRNA genes are frequently located near mouse cancer susceptibility loci

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Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

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Silencing of the Imprinted DLK1-MEG3 Locus in Human Clinically Nonfunctioning Pituitary Adenomas

21 January 2018

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Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis

21 January 2018

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Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31.

21 January 2018

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Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues

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Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

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Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia

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Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma

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Altered MicroRNA expression in cervical carcinomas

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DLK1-DIO3 Genomic Imprinted MicroRNA Cluster at 14q32.2 Defines a Stemlike Subtype of Hepatocellular Carcinoma Associated with Poor Survival

21 January 2018

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Facile means for quantifying microRNA expression by real-time PCR

21 January 2018

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Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays

21 January 2018

1 reference

The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis

21 January 2018

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Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis

21 January 2018

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Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene

21 January 2018

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Genomic imprinting at the mammalian Dlk1-Dio3 domain

21 January 2018

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Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels

21 January 2018

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A brain-specific microRNA regulates dendritic spine development

21 January 2018

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Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

21 January 2018

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MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1.

21 January 2018

1 reference

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

21 January 2018

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Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

21 January 2018

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A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

21 January 2018

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Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

21 January 2018

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Role of miR-143 targeting KRAS in colorectal tumorigenesis.

21 January 2018

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miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer

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Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.26573

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9 September 2017

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