Modeling neurodevelopmental and psychiatric diseases with human iPSCs (Q39130188)

9 September 2017

title

Modeling neurodevelopmental and psychiatric diseases with human iPSCs (English)

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9 September 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Zhexing Wen

series ordinal

1

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9 September 2017

publication date

10 February 2017

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Journal of Neuroscience Research

9 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

11 June 2020

volume

95

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

11 June 2020

issue

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

1097-1109

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages

11 June 2020

cites work

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Treatment-resistant depression: therapeutic trends, challenges, and future directions

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Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model

21 January 2018

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Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.

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Induced pluripotent stem cells: the new patient?

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Prenatal bisphenol A exposure and early childhood behavior

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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

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Modelling schizophrenia using human induced pluripotent stem cells

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Increased l1 retrotransposition in the neuronal genome in schizophrenia

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A human neurodevelopmental model for Williams syndrome

21 January 2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

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Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

21 January 2018

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Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients

21 January 2018

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Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

21 January 2018

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GABA system dysfunction in autism and related disorders: from synapse to symptoms

21 January 2018

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The 15q11.2 BP1-BP2 microdeletion syndrome: a review

21 January 2018

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Genetic architecture in autism spectrum disorder

21 January 2018

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Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice.

21 January 2018

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Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

21 January 2018

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Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening

21 January 2018

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Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice

21 January 2018

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Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo

21 January 2018

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Maternal immune activation: Implications for neuropsychiatric disorders.

21 January 2018

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Zika virus impairs growth in human neurospheres and brain organoids

21 January 2018

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Alterations in cortical network oscillations and parvalbumin neurons in schizophrenia

21 January 2018

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Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes

21 January 2018

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Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons

21 January 2018

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Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders.

21 January 2018

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Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons

21 January 2018

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Differentiation of human oligodendrocytes from pluripotent stem cells

21 January 2018

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Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

21 January 2018

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The 22q11.2 deletion syndrome as a window into complex neuropsychiatric disorders over the lifespan.

21 January 2018

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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

21 January 2018

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Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

21 January 2018

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Stem cells and stem cell-derived tissues and their use in safety assessment.

21 January 2018

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Directed differentiation of functional astroglial subtypes from human pluripotent stem cells

21 January 2018

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Cerebral organoids model human brain development and microcephaly

21 January 2018

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Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells

21 January 2018

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

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Cortical inhibitory neurons and schizophrenia

21 January 2018

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Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells

21 January 2018

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Specification of neuronal and glial subtypes from human pluripotent stem cells

21 January 2018

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Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells

21 January 2018

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Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits

21 January 2018

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Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

21 January 2018

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Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities

21 January 2018

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CNVs: harbingers of a rare variant revolution in psychiatric genetics

21 January 2018

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Imaging of fetal cytomegalovirus infection

21 January 2018

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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

21 January 2018

1 reference

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

21 January 2018

1 reference

Modeling human cortical development in vitro using induced pluripotent stem cells

21 January 2018

1 reference

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

21 January 2018

1 reference

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

21 January 2018

1 reference

Genome engineering of isogenic human ES cells to model autism disorders

21 January 2018

1 reference

Animal models of human disease: challenges in enabling translation

21 January 2018

1 reference

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

21 January 2018

1 reference

Zika Virus Associated with Microcephaly

21 January 2018

1 reference

Efficient derivation of microglia-like cells from human pluripotent stem cells

21 January 2018

1 reference

Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.

21 January 2018

1 reference

L1 retrotransposition in neurons is modulated by MeCP2

21 January 2018

1 reference

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

21 January 2018

1 reference

Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1.

21 January 2018

1 reference

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

21 January 2018

1 reference

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

21 January 2018

1 reference

Analysis of conditional heterozygous STXBP1 mutations in human neurons

21 January 2018

1 reference

Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient

21 January 2018

1 reference

Rapid Spread of Zika Virus in The Americas - Implications for Public Health Preparedness for Mass Gatherings at the 2016 Brazil Olympic Games

21 January 2018

1 reference

Alterations of GABAergic Signaling in Autism Spectrum Disorders

21 January 2018

1 reference

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

21 January 2018

1 reference

Zika Virus and Birth Defects — Reviewing the Evidence for Causality

21 January 2018

1 reference

Neural stem cell proliferation is decreased in schizophrenia, but not in depression.

21 January 2018

1 reference

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

21 January 2018

1 reference

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.

21 January 2018

1 reference

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

21 January 2018

1 reference

Neurodevelopmental basis of bipolar disorder: a critical appraisal

21 January 2018

1 reference

Next-generation regenerative medicine: organogenesis from stem cells in 3D culture

21 January 2018

1 reference

Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications

21 January 2018

1 reference

Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

21 January 2018

1 reference

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

21 January 2018

1 reference

Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis

21 January 2018

1 reference

The pathophysiology of schizophrenia disorders: perspectives from the spectrum

21 January 2018

1 reference

Insights into Cortical Oscillations Arising from Optogenetic Studies

21 January 2018

1 reference

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

21 January 2018

1 reference

A quantitative framework to evaluate modeling of cortical development by neural stem cells

21 January 2018

1 reference

Neuroligins and neurexins link synaptic function to cognitive disease

21 January 2018

1 reference

Genetic architectures of psychiatric disorders: the emerging picture and its implications

21 January 2018

1 reference

Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions

21 January 2018

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

21 January 2018

1 reference

KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome

21 January 2018

1 reference

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.

21 January 2018

1 reference

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.

21 January 2018

1 reference

Altered WNT Signaling in Human Induced Pluripotent Stem Cell Neural Progenitor Cells Derived from Four Schizophrenia Patients

21 January 2018

1 reference

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

21 January 2018

1 reference

Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients

21 January 2018

1 reference

Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages

21 January 2018

1 reference

Synaptic dysregulation in a human iPS cell model of mental disorders

21 January 2018

1 reference

Modeling psychiatric disorders with patient-derived iPSCs

21 January 2018

1 reference

Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity

21 January 2018

1 reference

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

21 January 2018

1 reference

Direct conversion of human fibroblasts to induced serotonergic neurons

21 January 2018

1 reference

Engineering Stem Cell Organoids

21 January 2018

1 reference

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

21 January 2018

1 reference

Modeling hippocampal neurogenesis using human pluripotent stem cells

21 January 2018

1 reference

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

21 January 2018

1 reference

Rapid single-step induction of functional neurons from human pluripotent stem cells

21 January 2018

1 reference

Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction

21 January 2018

1 reference

A high-throughput screen for Wnt/β-catenin signaling pathway modulators in human iPSC-derived neural progenitors

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JNR.24031

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28186671 AND SRC:MED&resulttype=core&format=json

11 June 2020

1 reference