PDK1 controls upstream PI3K expression and PIP3 generation. (Q39119229)

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6 March 2020

title

PDK1 controls upstream PI3K expression and PIP3 generation (English)

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Björn Stork

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Philip Böhler

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Alexandra Maria Alers

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object named as

A M Dieterle

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Christoph Peter

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Alexander Gray

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Nick R. Leslie

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Hisaaki Shinohara

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Sebastian Wesselborg

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author name string

H Keppeler

3

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N Berleth

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S Drießen

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N Hieke

7

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S Pietkiewicz

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A S Löffler

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T Kurosaki

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M Engelke

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J Wienands

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M Bonin

17

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language of work or name

English

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publication date

29 July 2013

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6 March 2020

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volume

33

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issue

23

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page(s)

3043-3053

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Phosphoinositide signalling in cancer: beyond PI3K and PTEN.

6 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The PKB/AKT pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

PTEN and the PI3-kinase pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt signalling in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The emerging mechanisms of isoform-specific PI3K signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Phosphoinositide phosphatases in cell biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The nuts and bolts of AGC protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Phosphorylation and activation of p70s6k by PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The PTEN-PI3K pathway: of feedbacks and cross-talks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Essential role of PDK1 in regulating cell size and development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Regulation of BCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Switching Akt: from survival signaling to deadly response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Reverse genetic studies of the DNA damage response in the chicken B lymphocyte line DT40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Discovery of Novel Forkhead Box O1 Inhibitors for Treating Type 2 Diabetes: Improvement of Fasting Glycemia in Diabetic db/db Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation: a 2009 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Phosphoinositide 3-kinase pathway activation in phosphate and tensin homolog (PTEN)-deficient prostate cancer cells is independent of receptor tyrosine kinases and mediated by the p110beta and p110delta catalytic subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

PKB and the mitochondria: AKTing on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Akt negatively regulates translation of the ternary complex factor Elk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

cAMP-responding element-binding protein and c-Ets1 interact in the regulation of ATP-dependent MUC5AC gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Regulation of p110delta PI 3-kinase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

A comprehensive map of the mTOR signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Functional genomics identifies TOR-regulated genes that control growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Chronic Protein Kinase B (PKB/c-akt) Activation Leads to Apoptosis Induced by Oxidative Stress-Mediated Foxo3a Transcriptional Up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.266

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23893244 AND SRC:MED&resulttype=core&format=json

6 March 2020

1 reference