Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy (Q39111448)

9 September 2017

title

Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy (English)

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9 September 2017

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extracellular vesicle

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

Raymond M. Schiffelers

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

author name string

L Jiang

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

publication date

31 January 2017

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9 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

volume

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

157-166

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28140387 AND SRC:MED&resulttype=core&format=json

mRNA-based therapeutics--developing a new class of drugs

11 June 2020

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Interaction and uptake of exosomes by ovarian cancer cells

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Mechanisms of endocytosis

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Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

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Biological functions and biogenesis of secreted bacterial outer membrane vesicles

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Immune modulation by bacterial outer membrane vesicles.

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Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

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The Host Shapes the Gut Microbiota via Fecal MicroRNA

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Extracellular vesicles: biology and emerging therapeutic opportunities.

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Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

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A novel platform for cancer therapy using extracellular vesicles

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Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

21 January 2018

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Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity

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Maximizing exosome colloidal stability following electroporation

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

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Extracellular vesicles for drug delivery.

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Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-g expression

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Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages

21 January 2018

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Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs

21 January 2018

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Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.

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Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

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A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy.

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Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

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Focus on Extracellular Vesicles: Development of Extracellular Vesicle-Based Therapeutic Systems

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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

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A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide

21 January 2018

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Engineered bacterial outer membrane vesicles with enhanced functionality

21 January 2018

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Stem Cell-Derived Extracellular Vesicles and Immune-Modulation

21 January 2018

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MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential

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Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

21 January 2018

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Mesenchymal stem cells deliver exogenous miRNAs to neural cells and induce their differentiation and glutamate transporter expression

21 January 2018

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Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth

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Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice

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MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells

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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

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Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines.

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Secreted monocytic miR-150 enhances targeted endothelial cell migration

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7 January 2021

Exosomes: immune properties and potential clinical implementations

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Routes and mechanisms of extracellular vesicle uptake

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PubMed

https://pubmed.ncbi.nlm.nih.gov/28140387

12 December 2020