CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation (Q39101587)

9 September 2017

title

CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation. (English)

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9 September 2017

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J Nie

1

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9 September 2017

L Liu

2

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9 September 2017

G Xing

3

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9 September 2017

M Zhang

4

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9 September 2017

R Wei

5

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9 September 2017

M Guo

6

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9 September 2017

X Li

7

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9 September 2017

P Xie

8

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9 September 2017

L Li

9

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9 September 2017

F He

10

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9 September 2017

W Han

11

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9 September 2017

L Zhang

12

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9 September 2017

language of work or name

English

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publication date

2 September 2013

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9 September 2017

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9 September 2017

volume

33

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9 September 2017

issue

28

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9 September 2017

page(s)

3677-3687

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Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2

9 September 2017

cites work

1 reference

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Role for the pleckstrin homology domain-containing protein CKIP-1 in phosphatidylinositol 3-kinase-regulated muscle differentiation.

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CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation

21 January 2018

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Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

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Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization.

21 January 2018

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SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1

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The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth

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Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.

21 January 2018

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HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation

21 January 2018

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The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint

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Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis

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Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways

21 January 2018

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DNA damage stress induces the dissociation of Smurf1/2 from MDM2 in a slow manner

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/ONC.2013.340

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9 September 2017

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