Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication. (Q39069527)

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scientific article published on 28 October 2013

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English	Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication.	scientific article published on 28 October 2013

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28 February 2020

Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication (English)

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28 February 2020

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28 February 2020

María Rosa López-Huertas

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28 February 2020

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28 February 2020

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Marta Montes

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28 February 2020

Immaculada Montanuy

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28 February 2020

Elena Mateos

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28 February 2020

Caroline Le Sommer

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28 February 2020

Mariano A Garcia-Blanco

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28 February 2020

Cristina Hernández-Munain

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28 February 2020

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28 February 2020

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28 February 2020

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28 February 2020

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28 February 2020

Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.

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Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.

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RNA polymerase II elongation control

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The control of HIV transcription: keeping RNA polymerase II on track

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Paused RNA polymerase II as a developmental checkpoint

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Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation

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HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

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Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila

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The transcriptional transactivator Tat selectively regulates viral splicing.

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9 September 2017

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

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Rates of in situ transcription and splicing in large human genes

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A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans

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9 September 2017

Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs

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The basal initiation machinery: beyond the general transcription factors

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Role of cellular RNA processing factors in human immunodeficiency virus type 1 mRNA metabolism, replication, and infectivity

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9 September 2017

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication

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Cracking the RNA polymerase II CTD code

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Identification of host proteins required for HIV infection through a functional genomic screen

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9 September 2017

Identification of the cellular targets of the transcription factor TCERG1 reveals a prevalent role in mRNA processing.

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RNA polymerase is poised for activation across the genome

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

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A chromatin landmark and transcription initiation at most promoters in human cells

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Controlling the elongation phase of transcription with P-TEFb

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Human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions.

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9 September 2017

HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs

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FF domains of CA150 bind transcription and splicing factors through multiple weak interactions

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The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo

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9 September 2017

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter

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Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II

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9 September 2017

Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner

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Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

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A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

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P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

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Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

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CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription

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Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

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The human immunodeficiency virus type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by Tat

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Control of RNA initiation and elongation at the HIV-1 promoter

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Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function

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Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes

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Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat

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HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors

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Contribution of the TATA motif to Tat-mediated transcriptional activation of human immunodeficiency virus gene expression

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Transcription regulation through promoter-proximal pausing of RNA polymerase II.

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Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors.

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TCERG1 regulates alternative splicing of the Bcl-x gene by modulating the rate of RNA polymerase II transcription.

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Transcriptional regulation of the Ig kappa gene by promoter-proximal pausing of RNA polymerase II.

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HIV enhancer activity perpetuated by NF-kappa B induction on infection of monocytes

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Rapid, real-time detection of acute HIV infection in patients in Africa

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A new strategy based on recombinant viruses as a tool for assessing drug susceptibility of human immunodeficiency virus type 1.

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Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

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Expression of IκBα in the nucleus of human peripheral blood T lymphocytes

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Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24165037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24165037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-4690-10-124

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24165037 AND SRC:MED&resulttype=core&format=json

28 February 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-4690-10-124

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24165037 AND SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24165037 AND SRC:MED&resulttype=core&format=json

28 February 2020

ResearchGate publication ID

0 references

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