New and Emerging Therapies and Targets: Beta-3 Agonists. (Q39062830)

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4 April 2020

title

New and Emerging Therapies and Targets: Beta-3 Agonists (English)

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4 April 2020

2

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4 April 2020

author name string

Lauriane Y M Michel

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

4 April 2020

publication date

1 January 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

Handbook of experimental pharmacology

4 April 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

4 April 2020

volume

243

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

4 April 2020

page(s)

205-223

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy

4 April 2020

cites work

1 reference

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Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation

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Differential Effects of Nebivolol and Metoprolol on Insulin Sensitivity and Plasminogen Activator Inhibitor in the Metabolic Syndrome

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Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase

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beta-adrenergic receptor blockade in chronic heart failure

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Beta-adrenoceptors in cardiac disease

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Exercise Protects Against Myocardial Ischemia–Reperfusion Injury via Stimulation of β 3 -Adrenergic Receptors and Increased Nitric Oxide Signaling: Role of Nitrite and Nitrosothiols

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Pharmacological characterization of a recently described human beta 3-adrenergic receptor mutant

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Upregulation of functional beta(3)-adrenergic receptor in the failing canine myocardium

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The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase

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Targeted disruption of the beta2 adrenergic receptor gene

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A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists

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Identification and importance of brown adipose tissue in adult humans

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Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

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Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

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Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality

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Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients.

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Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives.

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Endothelial beta3-adrenoceptors mediate vasorelaxation of human coronary microarteries through nitric oxide and endothelium-dependent hyperpolarization.

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Endothelial beta3-adrenoreceptors mediate nitric oxide-dependent vasorelaxation of coronary microvessels in response to the third-generation beta-blocker nebivolol.

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Cardiovascular effects of beta 3-adrenoceptor stimulation in perinephritic hypertension.

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Endothelium-derived hyperpolarising factors and associated pathways: a synopsis

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Molecular characterization of the human beta 3-adrenergic receptor

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G proteins and the heart

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Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout

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Depression of systolic and diastolic myocardial reserve during atrial pacing tachycardia in patients with dilated cardiomyopathy

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β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.

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Functional beta3-adrenoceptor in the human heart

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The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

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Beta3-adrenoceptors in the cardiovascular system

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Crosstalk of beta-adrenergic receptor subtypes through Gi blunts beta-adrenergic stimulation of L-type Ca2 channels in canine heart failure.

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Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells

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Regulation of endothelial nitric-oxide synthase (NOS) S-glutathionylation by neuronal NOS: evidence of a functional interaction between myocardial constitutive NOS isoforms

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β3 -AR and the vertebrate heart: a comparative view

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Downregulation of adenylylcyclase types V and VI mRNA levels in pacing-induced heart failure in dogs

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β3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na -K pump in hyperglycemia induced by insulin receptor blockade.

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Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure

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Heart failure with preserved ejection fraction: a clinical dilemma

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Epinephrine regulation of the endothelial nitric-oxide synthase: roles of RAC1 and beta3-adrenergic receptors in endothelial NO signaling.

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Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs.

21 January 2018

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Identification of the Cardiac Beta-Adrenergic Receptor Protein: Solubilization and Purification by Affinity Chromatography

21 January 2018

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Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor.

21 January 2018

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Cardiac endothelium-myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction

21 January 2018

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Nitrosylated hemoglobin levels in human venous erythrocytes correlate with vascular endothelial function measured by digital reactive hyperemia

21 January 2018

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Decreased stimulatory guanosine triphosphate binding protein in dogs with pressure-overload left ventricular failure

21 January 2018

1 reference

Coronary arteriolar vasoconstriction in myocardial ischaemia: reflexes, sympathetic nervous system, catecholamines.

21 January 2018

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Effect of heart failure on catecholamine granule morphology and storage in chromaffin cells

21 January 2018

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A novel mechanism for the treatment of angina, arrhythmias, and diastolic dysfunction: inhibition of late I(Na) using ranolazine

21 January 2018

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Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study

21 January 2018

1 reference

Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction.

21 January 2018

1 reference

Upregulation of beta(3)-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium

21 January 2018

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Real-time RT-PCR for the detection of beta-adrenoceptor messenger RNAs in small human endomyocardial biopsies.

21 January 2018

1 reference

Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase

21 January 2018

1 reference

Protecting the myocardium: a role for the beta2 adrenergic receptor in the heart

21 January 2018

1 reference

Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects

21 January 2018

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Catecholamine cardiotoxicity

21 January 2018

1 reference

beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2 current

21 January 2018

1 reference

Targeted disruption of the beta 3-adrenergic receptor gene.

21 January 2018

1 reference

Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group

21 January 2018

1 reference

Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy.

21 January 2018

1 reference

Cold-activated brown adipose tissue in healthy men

21 January 2018

1 reference

Clinical use of the β3 adrenoceptor agonist mirabegron in patients with overactive bladder syndrome

21 January 2018

1 reference

Functional brown adipose tissue in healthy adults

21 January 2018

1 reference

Anti-hypertrophic and anti-oxidant effect of beta3-adrenergic stimulation in myocytes requires differential neuronal NOS phosphorylation

21 January 2018

1 reference

Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1007/164_2016_88

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28035527 AND SRC:MED&resulttype=core&format=json

release_6cw4pzsgmveirjrtf6nicz75ay

4 April 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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