Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters. (Q39062505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

title

Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

author name string

Patricia Dauer

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

Ashok Saluja

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

Sulagna Banerjee

series ordinal

4

1 reference

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4 April 2020

publication date

23 December 2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

volume

17

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4 April 2020

issue

1

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4 April 2020

page(s)

7-12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

4 April 2020

cites work

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Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133 tumor initiating cells

17 June 2018

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17 June 2018

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The Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem Cells

17 June 2018

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Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

17 June 2018

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Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor-Dependent Akt Activation

17 June 2018

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The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival

17 June 2018

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Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer

17 June 2018

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TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer

17 June 2018

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Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1

17 June 2018

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Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases

17 June 2018

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Nanoparticle formulation of ormeloxifene for pancreatic cancer

17 June 2018

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Pancreatic cancer: The microenvironment needs attention too!

17 June 2018

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Ormeloxifene suppresses desmoplasia and enhances sensitivity of gemcitabine in pancreatic cancer

17 June 2018

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The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?

17 June 2018

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HES 1 is essential for chemoresistance induced by stellate cells and is associated with poor prognosis in pancreatic cancer

17 June 2018

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Paracrine SDF-1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells

17 June 2018

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Pancreatic cancer stem cells: new insight into a stubborn disease

17 June 2018

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Pancreatic ductal adenocarcinoma: From genetics to biology to radiobiology to oncoimmunology and all the way back to the clinic

17 June 2018

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Ormeloxifene efficiently inhibits ovarian cancer growth

17 June 2018

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Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

17 June 2018

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A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms

17 June 2018

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

17 June 2018

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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

17 June 2018

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Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo Chemoradiation

17 June 2018

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The role of inflammation in pancreatic cancer

17 June 2018

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Macrophages increase the resistance of pancreatic adenocarcinoma cells to gemcitabine by upregulating cytidine deaminase

17 June 2018

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Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

17 June 2018

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17 June 2018

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A starring role for stellate cells in the pancreatic cancer microenvironment

17 June 2018

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Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

17 June 2018

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17 June 2018

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Human pancreatic adenocarcinoma contains a side population resistant to gemcitabine

17 June 2018

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Role of radiation therapy in the management of pancreatic cancer

17 June 2018

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

17 June 2018

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

17 June 2018

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Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.

17 June 2018

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Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma

17 June 2018

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Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.

17 June 2018

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Hedgehog signaling and therapeutics in pancreatic cancer

17 June 2018

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

17 June 2018

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17 June 2018

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Side population in the pancreatic cancer cell lines SW1990 and CFPAC-1 is enriched with cancer stem-like cells.

17 June 2018

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17 June 2018

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17 June 2018

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Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis

17 June 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

17 June 2018

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The role of radiation therapy in pancreas cancer

17 June 2018

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Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance.

17 June 2018

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17 June 2018

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Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

17 June 2018

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Cancer-associated stromal fibroblasts promote pancreatic tumor progression

17 June 2018

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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

17 June 2018

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Reactive oxygen species: a breath of life or death?

17 June 2018

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

17 June 2018

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Battle-scarred pancreas: role of alcohol and pancreatic stellate cells in pancreatic fibrosis.

17 June 2018

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17 June 2018

Fibroblasts in cancer

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Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras

17 June 2018

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Vitamin A inhibits pancreatic stellate cell activation: implications for treatment of pancreatic fibrosis

17 June 2018

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

17 June 2018

1 reference

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ABCG2 -- a transporter for all seasons

17 June 2018

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The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

17 June 2018

1 reference

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Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta

17 June 2018

1 reference

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Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins.

17 June 2018

1 reference

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Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

17 June 2018

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17 June 2018

Inflammation and cancer

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Hypoxia-inducible expression of tumor-associated carbonic anhydrases

17 June 2018

1 reference

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Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis

17 June 2018

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Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.

17 June 2018

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Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

17 June 2018

1 reference

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Periostin promotes the chemotherapy resistance to gemcitabine in pancreatic cancer

17 June 2018

1 reference

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Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages.

21 August 2018

1 reference

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Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma

21 August 2018

1 reference

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Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

21 August 2018

1 reference

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Cancer: Macrophages limit chemotherapy

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28034553

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Contextual regulation of pancreatic cancer stem cell phenotype and radioresistance by pancreatic stellate cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28034553

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.PAN.2016.12.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034553 AND SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

28034553

1 reference