A brain in flame; do inflammasomes and pyroptosis influence stroke pathology? (Q39044501)

8 September 2017

title

A brain in flame; do inflammasomes and pyroptosis influence stroke pathology? (English)

1 reference

8 September 2017

1 reference

3

1 reference

8 September 2017

Jack Barrington

1

0 references

author name string

Eloise Lemarchand

series ordinal

2

1 reference

8 September 2017

language of work or name

1 reference

20 December 2016

1 reference

8 September 2017

1 reference

8 September 2017

volume

27

1 reference

8 September 2017

issue

2

1 reference

8 September 2017

page(s)

205-212

1 reference

Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice

8 September 2017

cites work

1 reference

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

21 January 2018

1 reference

Molecular pathophysiology of cerebral hemorrhage: secondary brain injury

21 January 2018

1 reference

Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis

21 January 2018

1 reference

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

21 January 2018

1 reference

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

Pyroptosis: host cell death and inflammation

21 January 2018

1 reference

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

21 January 2018

1 reference

Interleukin-1α and brain inflammation

21 January 2018

1 reference

Regulation of interleukin-1 in acute brain injury

21 January 2018

1 reference

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

21 January 2018

1 reference

Sterile inflammation: sensing and reacting to damage

21 January 2018

1 reference

P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH.

21 January 2018

1 reference

Cell volume regulation modulates NLRP3 inflammasome activation

21 January 2018

1 reference

Caspase-1: is IL-1 just the tip of the ICEberg?

21 January 2018

1 reference

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.

21 January 2018

1 reference

Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling.

21 January 2018

1 reference

Hemolysis-induced lethality involves inflammasome activation by heme

21 January 2018

1 reference

Release of interleukin-1α or interleukin-1β depends on mechanism of cell death

21 January 2018

1 reference

Intermittent fasting attenuates inflammasome activity in ischemic stroke

21 January 2018

1 reference

Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century

21 January 2018

1 reference

Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010

21 January 2018

1 reference

P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

21 January 2018

1 reference

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

21 January 2018

1 reference

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

1 reference

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

21 January 2018

1 reference

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

21 January 2018

1 reference

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

21 January 2018

1 reference

Ultra-sensitive molecular MRI of vascular cell adhesion molecule-1 reveals a dynamic inflammatory penumbra after strokes

21 January 2018

1 reference

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke

21 January 2018

1 reference

Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

21 January 2018

1 reference

Inflammasomes: mechanism of action, role in disease, and therapeutics

21 January 2018

1 reference

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

21 January 2018

1 reference

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

21 January 2018

1 reference

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

21 January 2018

1 reference

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

The immunology of stroke: from mechanisms to translation

21 January 2018

1 reference

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation

21 January 2018

1 reference

Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice

21 January 2018

1 reference

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury

21 January 2018

1 reference

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

21 January 2018

1 reference

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

21 January 2018

1 reference

NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO).

21 January 2018

1 reference

Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis

21 January 2018

1 reference

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

21 January 2018

1 reference

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

21 January 2018

1 reference

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

21 January 2018

1 reference

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression

21 January 2018

1 reference

Neurovascular protection by telmisartan via reducing neuroinflammation in stroke-resistant spontaneously hypertensive rat brain after ischemic stroke

21 January 2018

1 reference

Knockout of silent information regulator 2 (SIRT2) preserves neurological function after experimental stroke in mice

21 January 2018

1 reference

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

1 reference

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

21 January 2018

1 reference

Poststroke Inflammasome Expression and Regulation in the Peri-Infarct Area by Gonadal Steroids after Transient Focal Ischemia in the Rat Brain.

21 January 2018

1 reference

Activation and regulation of the inflammasomes

21 January 2018

1 reference

Inflammasomes link vascular disease with neuroinflammation and brain disorders

21 January 2018

1 reference

Minocycline Protects Against NLRP3 Inflammasome-Induced Inflammation and P53-Associated Apoptosis in Early Brain Injury After Subarachnoid Hemorrhage

21 January 2018

1 reference

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

1 reference

Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP

21 January 2018

1 reference

Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats

21 January 2018

1 reference

Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats

21 January 2018

1 reference

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

21 January 2018

1 reference

Novel role of PKR in inflammasome activation and HMGB1 release

21 January 2018

1 reference

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage

21 January 2018

1 reference

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage.

21 January 2018

1 reference

Stroke and the immune system: from pathophysiology to new therapeutic strategies

21 January 2018

1 reference

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

1 reference

Cell death and inflammation: the case for IL-1 family cytokines as the canonical DAMPs of the immune system

21 January 2018

1 reference

The HMGB1 receptor RAGE mediates ischemic brain damage

21 January 2018

1 reference

Interleukin-1 and acute brain injury

21 January 2018

1 reference

Interleukin 1α and the inflammatory process

21 January 2018

1 reference

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.

21 January 2018

1 reference

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

21 January 2018

1 reference

Caspase inhibitors are functionally neuroprotective against oxygen glucose deprivation induced CA1 death in rat organotypic hippocampal slices

21 January 2018

1 reference

Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury

21 January 2018

1 reference

Artificial Loading of ASC Specks with Cytosolic Antigens.

21 January 2018

1 reference

Reduced Ischemic Brain Injury in Interleukin-1β Converting Enzyme—Deficient Mice

21 January 2018

1 reference

21 January 2018

1 reference

Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.

21 January 2018

1 reference

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

21 January 2018

1 reference

Inflammasomes in the CNS.

21 January 2018

1 reference

Umbelliferone ameliorates cerebral ischemia-reperfusion injury via upregulating the PPAR gamma expression and suppressing TXNIP/NLRP3 inflammasome

21 January 2018

1 reference

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

21 January 2018

1 reference

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

21 January 2018

1 reference

Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

21 January 2018

1 reference

NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke

21 January 2018

1 reference

MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage

21 January 2018

1 reference

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

21 January 2018

1 reference

Recombinant adenovirus encoding NLRP3 RNAi attenuate inflammation and brain injury after intracerebral hemorrhage

21 January 2018

1 reference

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy

21 January 2018

1 reference

Chrysophanol inhibits NALP3 inflammasome activation and ameliorates cerebral ischemia/reperfusion in mice

21 January 2018

1 reference

Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats

21 January 2018

1 reference

A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat

21 January 2018

1 reference

21 January 2018

A growing global burden

1 reference

21 January 2018

Identifiers

DOI

10.1111/BPA.12476

1 reference

8 September 2017

1 reference