cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease. (Q39040344)

From Wikidata

Jump to navigation Jump to search

scientific article published on 23 December 2013

Language	Label	Description	Also known as
English	cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.	scientific article published on 23 December 2013

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

0 references

Alzheimer's disease

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Xavier Fant

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Emilie Durieu

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Bernard Payrastre

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Diego Sbrissa

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Assia Shisheva

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Emmanuelle Limanton

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

François Carreaux

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Jean-Pierre Bazureau

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

publication date

23 December 2013

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

Molecular Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

85

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

441-450

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6067634/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-mRNA splicing and human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of alternative splicing by a newly developed inhibitor of Clks

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium induces autophagy by inhibiting inositol monophosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing: a new drug target of the post-genome era.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TOR signaling in growth and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing: new insights from global analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticancer drug imatinib induces cellular autophagy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase: a universal regulator of autophagy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SR protein family of splicing factors: master regulators of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular stress and RNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIKfyve regulation of endosome-linked pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation mechanisms and signaling pathways of autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy regulation by p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eaten alive: a history of macroautophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy in mammalian development and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic lysosomal depletion in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy for tissue homeostasis and neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal membrane permeabilization in Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing of mRNA in the molecular pathology of neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 is activated in response to disruption of the pre-mRNA splicing machinery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myotonic Dystrophy Type 1 or Steinert’s Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing in oncogenesis and tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-mRNA splicing in disease and therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIKfyve and its Lipid products in health and in sickness

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The spliceosome as a target of novel antitumour drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detecting p53 isoforms at protein level

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic induction of autophagy to modulate neurodegenerative disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Latrepirdine (Dimebon®), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PtdIns5P: news and views of its appearance, disappearance and deeds

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vivo Regulation of Alternative Pre-mRNA Splicing by the Clk1 Protein Kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24366666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.113.090837

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24366666 AND SRC:MED&resulttype=core&format=json

3 March 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39040344&oldid=1959321640"