Phosphorylation mechanisms in dopamine transporter regulation. (Q39005712)

PubMed publication ID

8 September 2017

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title

Phosphorylation mechanisms in dopamine transporter regulation (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

1 reference

James D Foster

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

Roxanne A Vaughan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

publication date

8 November 2016

1 reference

PubMed publication ID

27836487

Journal of Chemical Neuroanatomy

8 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

volume

83-84

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

page(s)

10-18

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

Enhanced amphetamine- and K -mediated dopamine release in rat striatum after repeated amphetamine: differential requirements for Ca2 - and calmodulin-dependent phosphorylation and synaptic vesicles.

12 May 2020

cites work

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12 December 2020

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

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12 December 2020

Dopamine transporter antagonists block phorbol ester-induced dopamine release and dopamine transporter phosphorylation in striatal synaptosomes

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12 December 2020

Biogenic amine transporters: regulation in flux

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12 December 2020

Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.

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12 December 2020

Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine.

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12 December 2020

Dendrodendritic inhibition through reversal of dopamine transport

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12 December 2020

Dopamine transporters are phosphorylated on N-terminal serines in rat striatum

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12 December 2020

PI 3-kinase regulation of dopamine uptake.

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12 December 2020

N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization.

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12 December 2020

Dopamine transporters are dephosphorylated in striatal homogenates and in vitro by protein phosphatase 1.

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12 December 2020

Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity.

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12 December 2020

Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter

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12 December 2020

N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux

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12 December 2020

Pinning down cell signaling, cancer and Alzheimer's disease

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12 December 2020

Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta

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12 December 2020

Crystal structure of a bacterial homologue of Na /Cl--dependent neurotransmitter transporters

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12 December 2020

Differential effects of dopamine and psychoactive drugs on dopamine transporter phosphorylation and regulation

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12 December 2020

Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms.

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12 December 2020

Expression studies of naturally occurring human dopamine transporter variants identifies a novel state of transporter inactivation associated with Val382Ala.

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12 December 2020

Neurotransmitter transporters and their impact on the development of psychopharmacology

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12 December 2020

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

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12 December 2020

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

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12 December 2020

The functional impact of SLC6 transporter genetic variation

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12 December 2020

D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism.

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12 December 2020

Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations

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12 December 2020

Mechanisms of specificity in protein phosphorylation

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12 December 2020

Mitogenic signaling pathways induced by G protein-coupled receptors

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12 December 2020

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

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12 December 2020

Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors.

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12 December 2020

Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent.

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12 December 2020

Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol

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12 December 2020

An intracellular interaction network regulates conformational transitions in the dopamine transporter.

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12 December 2020

Anomalous dopamine release associated with a human dopamine transporter coding variant

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12 December 2020

Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

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12 December 2020

Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission

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12 December 2020

Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice

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12 December 2020

Proline-directed phosphorylation of the dopamine transporter N-terminal domain

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12 December 2020

Rapid substrate-induced down-regulation in function and surface localization of dopamine transporters: rat dorsal striatum versus nucleus accumbens

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12 December 2020

The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.

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12 December 2020

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges.

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12 December 2020

Dopamine transporter trafficking: rapid response on demand

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12 December 2020

Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression.

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12 December 2020

Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.

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12 December 2020

Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation

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12 December 2020

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

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12 December 2020

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

1 reference

12 December 2020

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

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12 December 2020

SLC6 neurotransmitter transporters: structure, function, and regulation

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12 December 2020

Proteins Interacting with Monoamine Transporters: Current State and Future Challenges

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12 December 2020

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

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12 December 2020

Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation

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12 December 2020

Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling

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12 December 2020

The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila.

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12 December 2020

Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux

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12 December 2020

Ca(2 )/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

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12 December 2020

Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression.

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12 December 2020

Importance of cholesterol in dopamine transporter function

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12 December 2020

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

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12 December 2020

Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding

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12 December 2020

SLC6 transporters: structure, function, regulation, disease association and therapeutics

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12 December 2020

Amphetamine-induced behavior requires CaMKII-dependent dopamine transporter phosphorylation.

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12 December 2020

Mechanisms of dopamine transporter regulation in normal and disease states

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12 December 2020

What is new for monoamine neurotransmitter disorders?

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12 December 2020

In vivo amphetamine action is contingent on αCaMKII

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12 December 2020

Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site

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12 December 2020

Amphetamines, new psychoactive drugs and the monoamine transporter cycle.

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12 December 2020

Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2 -containing membranes.

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12 December 2020

Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops

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12 December 2020

Neurotransmitter and psychostimulant recognition by the dopamine transporter

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12 December 2020

Spontaneous inward opening of the dopamine transporter is triggered by PIP2-regulated dynamics of the N-terminus

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12 December 2020

Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease

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12 December 2020

Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics

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12 December 2020

PKC phosphorylates residues in the N-terminal of the DA transporter to regulate amphetamine-induced DA efflux

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12 December 2020

Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters

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12 December 2020

Nitric oxide inhibits [3H]dopamine uptake.

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12 December 2020

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons

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12 December 2020

Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax

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12 December 2020

Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes

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12 December 2020

Profound neuronal plasticity in response to inactivation of the dopamine transporter

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12 December 2020

Delineation of an endogenous zinc-binding site in the human dopamine transporter

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12 December 2020

Protein kinase A activity may kinetically upregulate the striatal transporter for dopamine.

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12 December 2020

10.1016/J.JCHEMNEU.2016.10.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705611&resulttype=core&format=json

12 May 2020

PubMed publication ID

27836487

1 reference