Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells (Q38989539)

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English	Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

author name string

Brian D Cholewa

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Molly C Pellitteri-Hahn

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Cameron O Scarlett

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Nihal Ahmad

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

publication date

9 June 2014

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Europe PubMed Central

PMC publication ID

8 September 2017

Journal of Proteome Research

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Europe PubMed Central

PMC publication ID

8 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

5041-5050

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

The role of polo-like kinase 1 in carcinogenesis: cause or consequence?

1 reference

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The mechanism for molecular assembly of the proteasome

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Comparison of the quantitative performance of a Q-Exactive high-resolution mass spectrometer with that of a triple quadrupole tandem mass spectrometer for the analysis of illicit drugs in wastewater

1 reference

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Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreatic Cancer

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A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours

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Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation

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Otto Warburg's contributions to current concepts of cancer metabolism

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Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies

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Less label, more free: approaches in label-free quantitative mass spectrometry.

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Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery

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Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnover

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Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells

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Plk1-mediated phosphorylation of Topors regulates p53 stability

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BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity

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Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

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Polo-like kinase isoform expression is a prognostic factor in ovarian carcinoma

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p53-dependent repression of polo-like kinase-1 (PLK1).

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Targeting the ubiquitin-proteasome system for cancer therapy

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https://pubmed.ncbi.nlm.nih.gov/24884503

12 December 2020

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Pseudo internal standard approach for label-free quantitative proteomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/24884503

12 December 2020

based on heuristic

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Prognostic value of pololike kinase expression in melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24884503

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Polo-like kinase: a novel marker of proliferation: correlation with estrogen-receptor expression in human breast cancer

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Identifiers

10.1021/PR5002516

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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