Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450. (Q38978560)

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7 March 2020

title

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450 (English)

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7 March 2020

1

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Emanuela Tolosano

8

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Deborah Chiabrando

3

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author name string

Giada Ingoglia

2

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7 March 2020

Sonia Mercurio

4

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Emilia Turco

5

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Lorenzo Silengo

6

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Fiorella Altruda

7

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7 March 2020

language of work or name

English

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publication date

31 January 2014

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7 March 2020

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volume

146

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issue

5

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page(s)

1325-1338

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Therapeutic approaches to limit hemolysis-driven endothelial dysfunction: scavenging free heme to preserve vasculature homeostasis

7 March 2020

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1 reference

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The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

9 September 2017

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Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development

9 September 2017

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Control of intracellular heme levels: heme transporters and heme oxygenases

9 September 2017

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Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal

9 September 2017

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9 September 2017

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Heme scavenging and the other facets of hemopexin

9 September 2017

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Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin

9 September 2017

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Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload

9 September 2017

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Pharmacological and clinical aspects of heme oxygenase

9 September 2017

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A heme export protein is required for red blood cell differentiation and iron homeostasis

9 September 2017

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Cytochrome p450 and chemical toxicology

9 September 2017

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Heme as a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis

9 September 2017

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Cytochrome P450s and other enzymes in drug metabolism and toxicity

9 September 2017

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Identification of a human heme exporter that is essential for erythropoiesis

9 September 2017

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Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

9 September 2017

1 reference

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Ferritin, iron homeostasis, and oxidative damage1,2 1Guest Editor: Mario Comporti 2This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal.

9 September 2017

1 reference

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A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

9 September 2017

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9 September 2017

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Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites

9 September 2017

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Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture

9 September 2017

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The human hepatic cytochromes P450 involved in drug metabolism

9 September 2017

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Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

9 September 2017

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Metals as Regulators of Heme Metabolism

14 September 2017

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Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH.

14 September 2017

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Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells.

14 September 2017

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Egr-1 regulates the transcriptional repression of mouse δ-aminolevulinic acid synthase 1 by heme

25 September 2017

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Effect of drugs on heme synthesis in the liver

17 June 2018

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The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene.

17 June 2018

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Immunochemical evidence for an association of heme oxygenase with the microsomal electron transport system.

17 June 2018

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Regulation of cytochrome P-450 messenger RNA and apoprotein levels by heme

17 June 2018

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Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases

17 June 2018

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Mild iron overload in an African American man with SLC40A1 D270V.

21 August 2018

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Ferritin, iron homeostasis, and oxidative damage

21 August 2018

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Relevance of cytochrome P450 levels in the actions of enflurane and isoflurane in mice: studies on the haem pathway

21 August 2018

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Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital

21 August 2018

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12 December 2020

Further studies on the relationship of the stimulatory effects of phenobarbital and 3,4-benzpyrene on hepatic heme synthesis to their effects on hepatic microsomal drug oxidations

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12 December 2020

Delta-aminolevulinic acid synthetase. II. Induction in rat liver

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12 December 2020

Delta-aminolevulinic acid synthetase. I. Studies in liver homogenates

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12 December 2020

Heme and methemoglobin: Naturally occurring repressors of microsomal cytochrome

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12 December 2020

The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals

1 reference

12 December 2020

10.1053/J.GASTRO.2014.01.053

Identifiers

DOI

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7 March 2020

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7 March 2020

PubMed publication ID

24486949

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24486949 AND SRC:MED&resulttype=core&format=json