The crosstalk between long non-coding RNAs and PI3K in cancer (Q38972951)

8 September 2017

title

The crosstalk between long non-coding RNAs and PI3K in cancer (English)

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8 September 2017

Leonidas Benetatos

1

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8 September 2017

Evangelos Voulgaris

series ordinal

2

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8 September 2017

Georgios Vartholomatos

series ordinal

3

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8 September 2017

publication date

7 February 2017

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8 September 2017

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8 September 2017

volume

34

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8 September 2017

issue

3

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8 September 2017

page(s)

39

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Non-coding RNAs as direct and indirect modulators of epigenetic regulation

8 September 2017

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Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells

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Expanding the p53 regulatory network: LncRNAs take up the challenge

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LincRNA-p21 suppresses target mRNA translation

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Long noncoding RNAs in cell-fate programming and reprogramming

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Xist RNA is a potent suppressor of hematologic cancer in mice

21 January 2018

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Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.

21 January 2018

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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

21 January 2018

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Long non-coding RNAs control hematopoietic stem cell function

21 January 2018

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Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation

21 January 2018

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Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation

21 January 2018

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

21 January 2018

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Long noncoding RNAs in cancer: mechanisms of action and technological advancements

21 January 2018

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LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

A long noncoding RNA connects c-Myc to tumor metabolism.

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma.

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

LncRNA-MEG3 inhibits cell proliferation of endometrial carcinoma by repressing Notch signaling

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34 cells from patients with primary myelofibrosis and their clinical correlations.

21 January 2018

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DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer.

21 January 2018

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A cytoplasmic NF-κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasis

21 January 2018

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NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer.

21 January 2018

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Expression and prognostic impact of lncRNAs in acute myeloid leukemia

21 January 2018

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

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Long noncoding RNAs: fresh perspectives into the RNA world

21 January 2018

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Development of PI3K inhibitors: lessons learned from early clinical trials

21 January 2018

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p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?

21 January 2018

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New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer

21 January 2018

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Histone methylation modifiers in cellular signaling pathways

21 January 2018

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PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Functional compensation between Myc and PI3K signaling supports self-renewal of embryonic stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Akt mediates self-renewal division of mouse spermatogonial stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Hematopoietic Stem Cell Activity Is Regulated by Pten Phosphorylation Through a Niche-Dependent Mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Hypoxic Preconditioning Inhibits Hypoxia-induced Apoptosis of Cardiac Progenitor Cells via the PI3K/Akt-DNMT1-p53 Pathway

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Genomic Determinants of PI3K Pathway Inhibitor Response in Cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Targeting the phosphoinositide 3-kinase pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Mutation Profiling of Usual Ductal Hyperplasia of the Breast Reveals Activating Mutations Predominantly at Different Levels of the PI3K/AKT/mTOR Pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

PI3K pathway alterations in cancer: variations on a theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

PI3Kγ is a molecular switch that controls immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Suppression of the PI3K–Akt pathway is involved in the decreased adhesion and migration of bone marrow-derived mesenchymal stem cells from non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Myelodysplasia is in the niche: novel concepts and emerging therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Burning Fat Fuels Leukemic Stem Cell Heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Impairment of PI3K/AKT and WNT/β-catenin pathways in bone marrow mesenchymal stem cells isolated from patients with myelodysplastic syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Glycogen synthase kinase-3: a potential preventive target for prostate cancer management

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Expression signature of lncRNAs and their potential roles in cardiac fibrosis of post-infarct mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Long noncoding RNA-MEG3 is involved in diabetes mellitus-related microvascular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Osteopontin enhances the expression of HOTAIR in cancer cells via IRF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326.

21 January 2018

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https://api.crossref.org/works/10.1007/S12032-017-0897-2

Oncofetal H19 RNA promotes tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

HOXD-AS1 is a novel lncRNA encoded in HOXD cluster and a marker of neuroblastoma progression revealed via integrative analysis of noncoding transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12032-017-0897-2

A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division

21 January 2018

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12 December 2020

Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma

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12 December 2020

RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma.

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12 December 2020

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert)

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12 December 2020

Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer.

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12 December 2020

Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma

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12 December 2020

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature.

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12 December 2020

MEG3 imprinted gene contribution in tumorigenesis

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12 December 2020

Long noncoding RNA AK056155 involved in the development of Loeys-Dietz syndrome through AKT/PI3K signaling pathway

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12 December 2020

HULC long noncoding RNA silencing suppresses angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling pathway in human gliomas

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12 December 2020

MAPK1 up-regulates the expression of MALAT1 to promote the proliferation of cardiomyocytes through PI3K/AKT signaling pathway

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12 December 2020

Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

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12 December 2020

Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study.

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12 December 2020

Multiple myeloma cancer stem cells

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12 December 2020

Pharmacodynamic Biomarker Development for PI3K Pathway Therapeutics

1 reference

12 December 2020

10.1007/S12032-017-0897-2

Identifiers

DOI

1 reference

Dimensions Publication ID

8 September 2017

1083698677

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