Genomic Aberrations in Multiple Myeloma (Q38970573)

8 September 2017

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title

Genomic Aberrations in Multiple Myeloma (English)

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8 September 2017

5

Irene M Ghobrial

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8 September 2017

Salomon Manier

1

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8 September 2017

Karma Salem

series ordinal

2

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8 September 2017

Siobhan V Glavey

series ordinal

3

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8 September 2017

Aldo M Roccaro

series ordinal

4

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8 September 2017

publication date

1 January 2016

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Cancer Treatment and Research

8 September 2017

published in

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8 September 2017

volume

169

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8 September 2017

page(s)

23-34

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Familial risks and temporal incidence trends of multiple myeloma

8 September 2017

cites work

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https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

21 January 2018

1 reference

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Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Racial disparities in the prevalence of monoclonal gammopathies: a population-based study of 12,482 persons from the National Health and Nutritional Examination Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The genetic architecture of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The molecular classification of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Clinical and biologic implications of recurrent genomic aberrations in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Role of additional chromosomal changes in the prognostic value of t(4;14) and del(17p) in multiple myeloma: the IFM experience

21 January 2018

1 reference

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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

21 January 2018

1 reference

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Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p).

21 January 2018

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Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome.

21 January 2018

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https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Impact of genomic aberrations including chromosome 1 abnormalities on the outcome of patients with relapsed or refractory multiple myeloma treated with lenalidomide and dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Initial genome sequencing and analysis of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Deletions of CDKN2C in multiple myeloma: biological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Genetic aberrations and survival in plasma cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Mutational heterogeneity in cancer and the search for new cancer-associated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The exosome: a multipurpose RNA-decay machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Genetic variegation of clonal architecture and propagating cells in leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Hypodiploidy is a major prognostic factor in multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

1p21 deletions are strongly associated with 1q21 gains and are an independent adverse prognostic factor for the outcome of high-dose chemotherapy in patients with multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

Darwinian evolution and tiding clones in multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007/978-3-319-40320-5_3

10.1007/978-3-319-40320-5_3

31 March 2020

Identifiers

DOI

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