Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation (Q38953409)

7 September 2017

title

Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation (English)

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7 September 2017

main subject

neoplastic stem cells

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Naoya Hirata

1

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7 September 2017

Shigeru Yamada

2

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7 September 2017

Takuji Shoda

3

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7 September 2017

Masaaki Kurihara

4

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7 September 2017

Yuko Sekino

5

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7 September 2017

Yasunari Kanda

6

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7 September 2017

language of work or name

English

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publication date

25 September 2014

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7 September 2017

published in

Nature Communications

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7 September 2017

volume

5

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7 September 2017

page(s)

4806

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

7 September 2017

cites work

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Prospective identification of tumorigenic breast cancer cells

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer

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High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer

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ErbB receptor tyrosine kinase/NF-κB signaling controls mammosphere formation in human breast cancer

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In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

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Controversies in cancer stem cells: targeting embryonic signaling pathways

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Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

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"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets

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Molecular cloning and functional characterization of murine sphingosine kinase

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

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Sphingosine 1-phosphate and cancer

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An update on sphingosine-1-phosphate and other sphingolipid mediators

21 January 2018

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Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.

21 January 2018

1 reference

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

21 January 2018

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Nicotine increases cancer stem cell population in MCF-7 cells

21 January 2018

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Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

21 January 2018

1 reference

Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist

21 January 2018

1 reference

Targeting Notch to target cancer stem cells.

21 January 2018

1 reference

Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

21 January 2018

1 reference

Notch: The Past, the Present, and the Future

21 January 2018

1 reference

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

21 January 2018

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

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Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

21 January 2018

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Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide

21 January 2018

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Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation

21 January 2018

1 reference

Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

21 January 2018

1 reference

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

21 January 2018

1 reference

Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.

21 January 2018

1 reference

The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors

21 January 2018

1 reference

Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells

21 January 2018

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Regulation of stem cell pluripotency and neural differentiation by lysophospholipids

21 January 2018

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Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

21 January 2018

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Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

21 January 2018

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Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1.

21 January 2018

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TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

21 January 2018

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Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.

21 January 2018

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Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

21 January 2018

1 reference

High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

21 January 2018

1 reference

Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells

21 January 2018

1 reference

Notch signalling in solid tumours: a little bit of everything but not all the time

21 January 2018

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Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells

21 January 2018

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MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.

21 January 2018

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Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway

21 January 2018

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Spleen tyrosine kinase (Syk)-dependent calcium signals mediate efficient CpG-induced exocytosis of tumor necrosis factor α (TNFα) in innate immune cells

21 January 2018

1 reference

Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain

21 January 2018

1 reference

Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues

21 January 2018

1 reference

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 January 2018

1 reference

Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells

21 January 2018

1 reference

Aldehyde dehydrogenase (ALDH) activity does not select for cells with enhanced aggressive properties in malignant melanoma

21 January 2018

1 reference

Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Smooth Muscle alpha-actin is a direct target of Notch/CSL

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS5806

1 reference

Dimensions Publication ID

7 September 2017

0 references

1027818267

0 references

Fatcat ID

release_bcv72gjytfgu7jqzunzmx3pzbu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bcv72gjytfgu7jqzunzmx3pzbu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference