Cancer stem cells: understanding tumor hierarchy and heterogeneity (Q38950215)

26 September 2017

1 reference

25 January 2021

Cancer stem cells: understanding tumor hierarchy and heterogeneity (English)

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26 September 2017

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3 April 2019

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1 December 2020

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20 November 2020

genetic heterogeneity

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25 January 2021

neoplastic stem cells

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Jeremy N Rich

1

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PMC publication ID

5599210

26 September 2017

language of work or name

English

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publication date

1 September 2016

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26 September 2017

3 April 2019

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12 October 2019

18 September 2020

20 November 2020

1 December 2020

25 January 2021

8 references

26 September 2017

3 April 2019

30 June 2019

14 September 2019

12 October 2019

20 November 2020

1 December 2020

25 January 2021

95

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26 September 2017

1 Suppl 1

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26 September 2017

S2-7

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Creative Commons Attribution-NonCommercial 4.0 International

26 September 2017

8 references

3 April 2019

30 June 2019

14 September 2019

12 October 2019

18 September 2020

20 November 2020

1 December 2020

on focus list of Wikimedia project

25 January 2021

ScienceSource

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Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells

27 September 2017

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Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity

27 September 2017

1 reference

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Cancer stem cells in glioblastoma

27 September 2017

1 reference

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Cancer stem cells: the promise and the potential.

27 September 2017

1 reference

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The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?

27 September 2017

1 reference

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Cancer stem cell plasticity and tumor hierarchy

27 September 2017

1 reference

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Emerging understanding of multiscale tumor heterogeneity

27 September 2017

1 reference

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Targeting cancer stem-like cells as an approach to defeating cellular heterogeneity in Ewing sarcoma

27 September 2017

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Blocking the formation of radiation-induced breast cancer stem cells

27 September 2017

1 reference

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A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms

27 September 2017

1 reference

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Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance.

27 September 2017

1 reference

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The colon cancer stem cell microenvironment holds keys to future cancer therapy

27 September 2017

1 reference

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GBM's multifaceted landscape: highlighting regional and microenvironmental heterogeneity

27 September 2017

1 reference

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Evolution of the cancer stem cell model

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation

27 September 2017

1 reference

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The causes and consequences of genetic heterogeneity in cancer evolution

27 September 2017

1 reference

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Tumour heterogeneity and cancer cell plasticity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Characterization of the stem cell niche and its importance in radiobiological response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Radiation-induced Notch signaling in breast cancer stem cells

27 September 2017

1 reference

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Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Overview of cancer stem cells (CSCs) and mechanisms of their regulation: implications for cancer therapy.

27 September 2017

1 reference

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Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features.

27 September 2017

1 reference

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

27 September 2017

1 reference

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Complexity of cancer stem cells

27 September 2017

1 reference

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Cancer stem cells: current status and evolving complexities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Stem cells in breast tumours: are they ready for the clinic?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Understanding cancer stem cell heterogeneity and plasticity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

27 September 2017

1 reference

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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

27 September 2017

1 reference

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Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

27 September 2017

1 reference

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The Origins and Implications of Intratumor Heterogeneity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Macrophage diversity enhances tumor progression and metastasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Stem-like ovarian cancer cells can serve as tumor vascular progenitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

let-7 regulates self renewal and tumorigenicity of breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Cancer stem cells: an old idea--a paradigm shift

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Studies of the dissemination and quantitative transplantation of a lymphocytic leukaemia of CBA mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Leukaemia stem cells and the evolution of cancer-stem-cell research.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

Ontogeny, pathology, oncology.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599210

A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo

21 August 2018

1 reference

12 December 2020

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

1 reference

12 December 2020

Looking ahead in cancer stem cell research

1 reference

12 December 2020

Metastasis results from preexisting variant cells within a malignant tumor

1 reference

12 December 2020

10.1097/MD.0000000000004764

Identifiers

DOI

1 reference

26 September 2017

1 reference

PMC publication ID

5599210

26 September 2017

PubMed publication ID

27611934

1 reference

PMC publication ID

5599210