Specification and epigenetic programming of the human germ line (Q38940310)

7 September 2017

1 reference

title

Specification and epigenetic programming of the human germ line (English)

1 reference

7 September 2017

4

Sabine Dietmann

1 reference

7 September 2017

Walfred W C Tang

1

1 reference

7 September 2017

Toshihiro Kobayashi

series ordinal

2

1 reference

7 September 2017

Naoko Irie

series ordinal

3

1 reference

7 September 2017

M Azim Surani

series ordinal

5

1 reference

7 September 2017

publication date

30 August 2016

1 reference

7 September 2017

published in

Nature Reviews Genetics

1 reference

7 September 2017

volume

17

1 reference

7 September 2017

issue

10

1 reference

7 September 2017

page(s)

585-600

1 reference

A signaling principle for the specification of the germ cell lineage in mice

7 September 2017

cites work

1 reference

Blimp1 is a critical determinant of the germ cell lineage in mice

31 March 2020

1 reference

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

31 March 2020

1 reference

Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance

31 March 2020

1 reference

A tripartite transcription factor network regulates primordial germ cell specification in mice

31 March 2020

1 reference

How to make a primordial germ cell

31 March 2020

1 reference

Induction of mouse germ-cell fate by transcription factors in vitro.

31 March 2020

1 reference

The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells

31 March 2020

1 reference

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine

31 March 2020

1 reference

Global profiling of DNA methylation erasure in mouse primordial germ cells

31 March 2020

1 reference

Epigenetic reprogramming in mouse primordial germ cells

31 March 2020

1 reference

X chromosome reactivation initiates in nascent primordial germ cells in mice

31 March 2020

1 reference

X chromosome activity in mouse XX primordial germ cells

31 March 2020

1 reference

Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice

31 March 2020

1 reference

Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice

31 March 2020

1 reference

Primordial germ cells in the mouse

31 March 2020

1 reference

Primordial germ-cell development and epigenetic reprogramming in mammals

31 March 2020

1 reference

Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

31 March 2020

1 reference

Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos.

31 March 2020

1 reference

Germ cell specification requires zygotic mechanisms rather than germ plasm in a basally branching insect

31 March 2020

1 reference

Gene function in mouse embryogenesis: get set for gastrulation

31 March 2020

1 reference

A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants

31 March 2020

1 reference

Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse

31 March 2020

1 reference

Bmp4 is required for the generation of primordial germ cells in the mouse embryo

31 March 2020

1 reference

Requirement ofBmp8bfor the Generation of Primordial Germ Cells in the Mouse

31 March 2020

1 reference

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

31 March 2020

1 reference

Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo

31 March 2020

1 reference

Smad5 is required for mouse primordial germ cell development

31 March 2020

1 reference

Requirement for Wnt3 in vertebrate axis formation

31 March 2020

1 reference

Nodal signalling in the epiblast patterns the early mouse embryo

31 March 2020

1 reference

Axis development and early asymmetry in mammals

31 March 2020

1 reference

A flattened mouse embryo: leveling the playing field

31 March 2020

1 reference

BMP signals and the transcriptional repressor BLIMP1 during germline segregation in the mammalian embryo

31 March 2020

1 reference

Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo

31 March 2020

1 reference

Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation

31 March 2020

1 reference

SOX17 is a critical specifier of human primordial germ cell fate

31 March 2020

1 reference

Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells.

31 March 2020

1 reference

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

31 March 2020

1 reference

The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo

31 March 2020

1 reference

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

31 March 2020

1 reference

The ground state of embryonic stem cell self-renewal

31 March 2020

1 reference

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

31 March 2020

1 reference

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

31 March 2020

1 reference

Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation

31 March 2020

1 reference

Dynamic Pluripotent Stem Cell States and Their Applications

31 March 2020

1 reference

Dynamic stem cell states: naive to primed pluripotency in rodents and humans

31 March 2020

1 reference

Derivation of novel human ground state naive pluripotent stem cells

31 March 2020

1 reference

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

31 March 2020

1 reference

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.

31 March 2020

1 reference

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory

31 March 2020

1 reference

Resetting transcription factor control circuitry toward ground-state pluripotency in human

31 March 2020

1 reference

Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.

31 March 2020

1 reference

The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak.

31 March 2020

1 reference

Reorganization of enhancer patterns in transition from naive to primed pluripotency

31 March 2020

1 reference

Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells

31 March 2020

1 reference

Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development

31 March 2020

1 reference

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

31 March 2020

1 reference

Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice

31 March 2020

1 reference

A molecular programme for the specification of germ cell fate in mice

31 March 2020

1 reference

The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse

31 March 2020

1 reference

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

31 March 2020

1 reference

Regulation and functions of Blimp-1 in T and B lymphocytes

31 March 2020

1 reference

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

31 March 2020

1 reference

PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells

31 March 2020

1 reference

Transcription factor gene AP-2 gamma essential for early murine development

31 March 2020

1 reference

ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

31 March 2020

1 reference

Co-repressor CBFA2T2 regulates pluripotency and germline development

31 March 2020

1 reference

PRDM proteins: important players in differentiation and disease

31 March 2020

1 reference

Oct-4: a germline-specific transcription factor mapping to the mouse t-complex

31 March 2020

1 reference

Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling

31 March 2020

1 reference

Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells

31 March 2020

1 reference

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state.

31 March 2020

1 reference

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

31 March 2020

1 reference

Reprogramming primordial germ cells into pluripotent stem cells

31 March 2020

1 reference

Oct4 is required for primordial germ cell survival

31 March 2020

1 reference

Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells

31 March 2020

1 reference

Nanog safeguards pluripotency and mediates germline development

31 March 2020

1 reference

Essential role of Sox2 for the establishment and maintenance of the germ cell line

31 March 2020

1 reference

Sall4 is essential for mouse primordial germ cell specification by suppressing somatic cell program genes

31 March 2020

1 reference

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells

31 March 2020

1 reference

The early human germ cell lineage does not express SOX2 during in vivo development or upon in vitro culture

31 March 2020

1 reference

Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications

31 March 2020

1 reference

Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis

31 March 2020

1 reference

The sox family of transcription factors: versatile regulators of stem and progenitor cell fate

31 March 2020

1 reference

Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

31 March 2020

1 reference

Sox proteins: regulators of cell fate specification and differentiation

31 March 2020

1 reference

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

31 March 2020

1 reference

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

31 March 2020

1 reference

Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells

31 March 2020

1 reference

Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate

31 March 2020

1 reference

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

31 March 2020

1 reference

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

31 March 2020

1 reference

Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells

31 March 2020

1 reference

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

31 March 2020

1 reference

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

31 March 2020

1 reference

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells

31 March 2020

1 reference

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos.

31 March 2020

1 reference

Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

31 March 2020

1 reference

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

31 March 2020

1 reference

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

31 March 2020

1 reference

Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice

31 March 2020

1 reference

A replication-dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells

31 March 2020

1 reference

Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

31 March 2020

1 reference

Parallel mechanisms of epigenetic reprogramming in the germline

31 March 2020

1 reference

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming

31 March 2020

1 reference

Role of Tet1 in erasure of genomic imprinting

31 March 2020

1 reference

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

31 March 2020

1 reference

Tet1 controls meiosis by regulating meiotic gene expression

31 March 2020

1 reference

DNA Demethylation Dynamics in the Human Prenatal Germline

31 March 2020

1 reference

Immunohistochemical Profiling of Germ Cells Within the Human Fetal Testis: Identification of Three Subpopulations

31 March 2020

1 reference

Expression of pluripotent stem cell markers in the human fetal ovary

31 March 2020

1 reference

Expression of pluripotent stem cell markers in the human fetal testis

31 March 2020

1 reference

DNA methylation: roles in mammalian development

31 March 2020

1 reference

Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b

31 March 2020

1 reference

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

31 March 2020

1 reference

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

31 March 2020

1 reference

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells

31 March 2020

1 reference

In vivo epigenomic profiling of germ cells reveals germ cell molecular signatures

31 March 2020

1 reference

Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

31 March 2020

1 reference

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos

31 March 2020

1 reference

The DNA methylation landscape of human early embryos

31 March 2020

1 reference

DNA methylation dynamics of the human preimplantation embryo

31 March 2020

1 reference

Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse

31 March 2020

1 reference

New concepts in DNA methylation

31 March 2020

1 reference

Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family

31 March 2020

1 reference

An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons

31 March 2020

1 reference

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints

31 March 2020

1 reference

Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57

31 March 2020

1 reference

Discovery and Characterization of piRNAs in the Human Fetal Ovary

31 March 2020

1 reference

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

31 March 2020

1 reference

Understanding transgenerational epigenetic inheritance via the gametes in mammals

31 March 2020

2 references

31 March 2020

12 December 2020

Molecular insights into transgenerational non-genetic inheritance of acquired behaviours.

1 reference

Transgenerational epigenetic inheritance: myths and mechanisms

31 March 2020

1 reference

Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis

31 March 2020

1 reference

Completion of mouse embryogenesis requires both the maternal and paternal genomes

31 March 2020

1 reference

In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

31 March 2020

1 reference

Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome

31 March 2020

1 reference

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

31 March 2020

1 reference

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

31 March 2020

1 reference

Primordial germ cells: the first cell lineage or the last cells standing?

31 March 2020

1 reference

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro.

31 March 2020

1 reference

Pax6 is a human neuroectoderm cell fate determinant

31 March 2020

1 reference

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

31 March 2020

1 reference

Totipotency and lineage segregation in the human embryo.

31 March 2020

1 reference

Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse

31 March 2020

1 reference

Tracking the progression of the human inner cell mass during embryonic stem cell derivation

31 March 2020

1 reference

Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation

31 March 2020

1 reference

Regulatory principles of pluripotency: from the ground state up.

31 March 2020

1 reference

Establishment in culture of pluripotential cells from mouse embryos

31 March 2020

1 reference

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

31 March 2020

1 reference

Derivation of pluripotent epiblast stem cells from mammalian embryos

31 March 2020

1 reference

New cell lines from mouse epiblast share defining features with human embryonic stem cells

31 March 2020

1 reference

In Vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation.

31 March 2020

1 reference

Embryonic stem cells can form germ cells in vitro

31 March 2020

1 reference

Derivation of oocytes from mouse embryonic stem cells

31 March 2020

1 reference

Self-renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro

31 March 2020

1 reference

Embryonic stem cell lines derived from human blastocysts

31 March 2020

1 reference

Naive and primed pluripotent states

31 March 2020

1 reference

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

31 March 2020

1 reference

Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency

31 March 2020

1 reference

Spontaneous differentiation of germ cells from human embryonic stem cells in vitro

31 March 2020

1 reference

Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs.

31 March 2020

1 reference

Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells

31 March 2020

1 reference

DNA methylation pathways and their crosstalk with histone methylation

31 March 2020

1 reference

The ontogeny of cKIT human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation.

31 March 2020

1 reference

Requirement of Bmp8b for the generation of primordial germ cells in the mouse

31 March 2020

1 reference

12 December 2020

X-chromosome activity of the mouse primordial germ cells revealed by the expression of an X-linked lacZ transgene

1 reference

12 December 2020

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance

1 reference

12 December 2020

Clonal analysis of the origin of primordial germ cells in the mouse

1 reference

12 December 2020

Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.

1 reference

12 December 2020

Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development.

1 reference

12 December 2020

Depletion of definitive gut endoderm in Sox17-null mutant mice

1 reference

12 December 2020

Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

1 reference

12 December 2020

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

1 reference

12 December 2020

X-chromosome activity in foetal germ cells of the mouse

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRG.2016.88

1 reference

Dimensions Publication ID

7 September 2017

1039236267

0 references

1 reference