Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling (Q38910230)

7 September 2017

Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling (English)

1 reference

7 September 2017

Adam Byron

3

0 references

Guillaume Jacquemet

Guillaume Jacquemet

2

0 references

Jonathan D Humphries

Jonathan D Humphries

8

0 references

Martin J. Humphries

Martin J Humphries

9

0 references

Stacey Warwood

5

Stacey Warwood

1 reference

7 September 2017

Joseph Robertson

1

1 reference

7 September 2017

Matthew C Jones

4

1 reference

7 September 2017

Julian N Selley

6

1 reference

7 September 2017

David Knight

7

1 reference

7 September 2017

language of work or name

English

0 references

publication date

13 February 2015

1 reference

7 September 2017

Nature Communications

1 reference

7 September 2017

6

1 reference

7 September 2017

6265

1 reference

Creative Commons Attribution 4.0 International

7 September 2017

start time

13 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis

9 September 2017

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ProteomeXchange provides globally coordinated proteomics data submission and dissemination

9 September 2017

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The integrin adhesome: from genes and proteins to human disease

9 September 2017

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Dynamic regulation of the structure and functions of integrin adhesions

9 September 2017

1 reference

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Why nature chose phosphate to modify proteins

9 September 2017

1 reference

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Opening the floodgates: proteomics and the integrin adhesome

9 September 2017

1 reference

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Sample preparation and analytical strategies for large-scale phosphoproteomics experiments

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment

9 September 2017

1 reference

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Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

9 September 2017

1 reference

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Quantitative proteomics of the integrin adhesome show a myosin II‐dependent recruitment of LIM domain proteins

9 September 2017

1 reference

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Cytoscape 2.8: new features for data integration and network visualization

9 September 2017

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Subcellular phosphoproteomics

9 September 2017

1 reference

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The switchable integrin adhesome.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

9 September 2017

1 reference

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Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6

9 September 2017

1 reference

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Evolution of complexity in the integrin adhesome.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Genetic and cell biological analysis of integrin outside-in signaling.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

9 September 2017

Paxillin comes of age

1 reference

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GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

9 September 2017

1 reference

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Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Functional atlas of the integrin adhesome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Integrin-regulated FAK-Src signaling in normal and cancer cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

p130Cas: a versatile scaffold in signaling networks

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Mammalian cyclin-dependent kinases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Integrin-dependent pathologies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

DAVID: Database for Annotation, Visualization, and Integrated Discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Integrin signaling revisited

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Probability-based protein identification by searching sequence databases using mass spectrometry data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

A strategy for identifying gel-separated proteins in sequence databases by MS alone.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Confident phosphorylation site localization using the Mascot Delta Score

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Phosphotyrosine Signaling: Evolving a New Cellular Communication System

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Measurement of protein tyrosine phosphorylation in cell adhesion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Integrated network analysis platform for protein-protein interactions

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Cell cycle synchronization at the G2/M phase border by reversible inhibition of CDK1.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

Increased expression of a high molecular weight (130 KD) protein kinase C isoform in a differentiation-defective ras-transfected keratinocyte line

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338609

22 August 2018

Identifiers

DOI

10.1038/NCOMMS7265

1 reference

Dimensions Publication ID

7 September 2017

0 references

0 references

1 reference

7 September 2017

PubMed publication ID

25677187

1 reference