EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival (Q38904675)

7 September 2017

title

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival (English)

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7 September 2017

11

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4 June 2020

Naiyang Fu

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4 June 2020

Bhupinder Pal

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Aaron Lun

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4 June 2020

Sarah A Best

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4 June 2020

Philippe Bouillet

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4 June 2020

Thomas Preiss

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4 June 2020

Geoffrey J. Lindeman

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4 June 2020

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Jane E Visvader

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4 June 2020

9

François Vaillant

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4 June 2020

author name string

Anne C Rios

2

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4 June 2020

Rina Soetanto

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4 June 2020

Kevin Liu

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4 June 2020

Tamara Beck

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4 June 2020

Gordon K Smyth

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4 June 2020

publication date

2 March 2015

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7 September 2017

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4 June 2020

volume

17

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4 June 2020

issue

4

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4 June 2020

page(s)

365-375

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Key stages in mammary gland development: the mammary end bud as a motile organ.

4 June 2020

cites work

1 reference

Involution: apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ

21 January 2018

1 reference

Stat3 controls lysosomal-mediated cell death in vivo

21 January 2018

1 reference

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

21 January 2018

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Many players in BCL-2 family affairs

21 January 2018

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Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation.

21 January 2018

1 reference

BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms

21 January 2018

1 reference

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

21 January 2018

1 reference

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

1 reference

Mcl-1 is essential for germinal center formation and B cell memory

21 January 2018

1 reference

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

21 January 2018

1 reference

Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function

21 January 2018

1 reference

Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage

21 January 2018

1 reference

Mcl-1 regulates the survival of adult neural precursor cells

21 January 2018

1 reference

Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure

21 January 2018

1 reference

Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction

21 January 2018

1 reference

In situ identification of bipotent stem cells in the mammary gland.

21 January 2018

1 reference

Programming cancer cells for high expression levels of Mcl1.

21 January 2018

1 reference

Delving deeper: MCL-1's contributions to normal and cancer biology

21 January 2018

1 reference

Mcl-1; the molecular regulation of protein function

21 January 2018

1 reference

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

21 January 2018

1 reference

Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis.

21 January 2018

1 reference

Targeting mammary epithelial cells using a bacterial artificial chromosome

21 January 2018

1 reference

Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine.

21 January 2018

1 reference

Gene regulatory networks in lactation: identification of global principles using bioinformatics.

21 January 2018

1 reference

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

21 January 2018

1 reference

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

21 January 2018

1 reference

Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1.

21 January 2018

1 reference

ERBB receptors and cancer: the complexity of targeted inhibitors

21 January 2018

1 reference

Molecular mechanisms of mTOR-mediated translational control

21 January 2018

1 reference

A unifying model for mTORC1-mediated regulation of mRNA translation.

21 January 2018

1 reference

TOR signaling in growth and metabolism

21 January 2018

1 reference

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

21 January 2018

1 reference

mTORC1 promotes survival through translational control of Mcl-1.

21 January 2018

1 reference

Physiological roles of ribosomal protein S6: one of its kind

21 January 2018

1 reference

Identification of multipotent mammary stem cells by protein C receptor expression.

21 January 2018

1 reference

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

21 January 2018

1 reference

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

21 January 2018

1 reference

Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.

21 January 2018

1 reference

ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition

21 January 2018

1 reference

Pan-mammalian target of rapamycin (mTOR) inhibitor AZD8055 primes rhabdomyosarcoma cells for ABT-737-induced apoptosis by down-regulating Mcl-1 protein

21 January 2018

1 reference

Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer

21 January 2018

1 reference

Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway

21 January 2018

1 reference

Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

21 January 2018

1 reference

Cre-mediated gene deletion in the mammary gland

21 January 2018

1 reference

Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development.

21 January 2018

1 reference

Generation of a functional mammary gland from a single stem cell

21 January 2018

1 reference

Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism

21 January 2018

1 reference

Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.

21 January 2018

1 reference

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

21 January 2018

1 reference

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

21 January 2018

1 reference

A scaling normalization method for differential expression analysis of RNA-seq data

21 January 2018

1 reference

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

21 January 2018

1 reference

voom: Precision weights unlock linear model analysis tools for RNA-seq read counts

21 January 2018

1 reference

Testing significance relative to a fold-change threshold is a TREAT.

21 January 2018

1 reference

Gene ontology analysis for RNA-seq: accounting for selection bias

21 January 2018

1 reference

Methods to analyze microRNA-mediated control of mRNA translation

21 January 2018

1 reference

c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland

21 January 2018

1 reference

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25730472