Therapeutic Potential of Genipin in Central Neurodegenerative Diseases (Q38891142)

7 September 2017

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title

Therapeutic Potential of Genipin in Central Neurodegenerative Diseases (English)

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7 September 2017

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3

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7 September 2017

Yanwei Li

1

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7 September 2017

Lin Li

series ordinal

2

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7 September 2017

publication date

9 July 2016

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7 September 2017

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7 September 2017

volume

30

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7 September 2017

issue

10

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7 September 2017

page(s)

889-897

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Ageing and inflammation - A central role for mitochondria in brain health and disease

7 September 2017

cites work

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Pathway as a pharmacological target for herbal medicines: an investigation from reduning injection

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Fructus Gardenia (Gardenia jasminoides J. Ellis) phytochemistry, pharmacology of cardiovascular, and safety with the perspective of new drugs development

21 January 2018

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Chronic administration of anti-stroke herbal medicine TongLuoJiuNao reduces amyloidogenic processing of amyloid precursor protein in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin attenuates lipopolysaccharide-induced persistent changes of emotional behaviors and neural activation in the hypothalamic paraventricular nucleus and the central amygdala nucleus

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

'Genipin' - the natural water soluble cross-linking agent and its importance in the modified drug delivery systems: an overview

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Anti-inflammatory evaluation of gardenia extract, geniposide and genipin

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Antiangiogenic activity of Gardenia jasminoides fruit

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Antithrombotic effect of geniposide and genipin in the mouse thrombosis model

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Natural Products for Chemoprevention of Breast Cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin exhibits neurotrophic effects through a common signaling pathway in nitric oxide synthase-expressing cells

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Antidepressant-like effect of genipin in mice

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Neuroinflammation in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Systemic infections and inflammation affect chronic neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Peripheral inflammatory biomarkers and risk of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Inflammation in Parkinson's disease: role of glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Innate immunity in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Complex deregulation and expression of cytokines and mediators of the immune response in Parkinson's disease brain is region dependent.

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits the inflammatory response of rat brain microglial cells.

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-induced iNOS and COX-2 expression via the NF-κB inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits lipopolysaccharide-induced acute systemic inflammation in mice as evidenced by nuclear factor-κB bioluminescent imaging-guided transcriptomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin protects lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Anti-inflammatory activity of iridoid and catechol derivatives from Eucommia ulmoides Oliver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

GDNF, NGF and BDNF as therapeutic options for neurodegeneration.

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Cyclic GMP-dependent neurite outgrowth by genipin and nerve growth factor in PC12h cells

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin suppresses A23187-induced cytotoxicity in neuro2a cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Prevention of the neurotoxicity of the amyloid beta protein by genipin

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Neuroprotection by genipin against reactive oxygen and reactive nitrogen species-mediated injury in organotypic hippocampal slice cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Gardenamide A attenuated cell apoptosis induced by serum deprivation insult via the ERK1/2 and PI3K/AKT signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Synthesis of stable genipin derivatives and studies of their neuroprotective activity in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Long‐acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Neuritogenic activity of a genipin derivative in retinal ganglion cells is mediated by retinoic acid receptor β expression through nitric oxide/S-nitrosylation signaling

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Requirement of retinoic acid receptor β for genipin derivative-induced optic nerve regeneration in adult rat retina

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Depressive symptoms in neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

The prevalence of depression in Alzheimer's disease: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Managing depression in Parkinson's patients: risk factors and clinical pearls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Antidepressants for neuro-regeneration: from depression to Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Integrating the monoamine, neurotrophin and cytokine hypotheses of depression--a central role for the serotonin transporter?

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Serotonergic drugs for depression and beyond

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

The hippocampus, neurotrophic factors and depression: possible implications for the pharmacotherapy of depression.

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

Faster, better, stronger: towards new antidepressant therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

An LC-MS method for simultaneous determination of five iridoids from Zhi-zi-chi Decoction in rat brain microdialysates and tissue homogenates: towards an in depth study for its antidepressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Antidepressant effect of Yueju-Wan ethanol extract and its fractions in mice models of despair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

1H-NMR-based metabonomic studies on the anti-depressant effect of genipin in the chronic unpredictable mild stress rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin ameliorates age-related insulin resistance through inhibiting hepatic oxidative stress and mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Uncoupling protein 2 negatively regulates glucose-induced glucagon-like peptide 1 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin inhibits mitochondrial uncoupling protein 2 expression and ameliorates podocyte injury in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Genipin stimulates glucose transport in C2C12 myotubes via an IRS-1 and calcium-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Hydroperoxy fatty acid cycling mediated by mitochondrial uncoupling protein UCP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40263-016-0369-9

Superoxide anion, uncoupling proteins and Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S40263-016-0369-9

The role of uncoupling proteins in diabetes mellitus

21 January 2018

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12 December 2020

Rapid Antidepressant Activity of Ethanol Extract of Gardenia jasminoides Ellis Is Associated with Upregulation of BDNF Expression in the Hippocampus

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12 December 2020

Genipin Attenuates Sepsis by Inhibiting Toll-Like Receptor Signaling

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12 December 2020

[Analysis on formula raw materials application of health food containing Gardeniae fructus]

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12 December 2020

Yueju pill rapidly induces antidepressant-like effects and acutely enhances BDNF expression in mouse brain

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12 December 2020

When does Parkinson's disease begin?

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12 December 2020

Drugs developed for treatment of diabetes show protective effects in Alzheimer's and Parkinson's diseases

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12 December 2020

Antiinflammatory effects of genipin, an active principle of gardenia

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12 December 2020

Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction

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12 December 2020

Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage Alzheimer's disease dementia

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12 December 2020

Commonality between Diabetes and Alzheimer's Disease and a New Strategy for the Therapy

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12 December 2020

Parkinson's Disease and Systemic Inflammation

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12 December 2020

The effect of stroke and other components in Xing-Nao-Jing on the pharmacokinetics of geniposide

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12 December 2020

Depression and Parkinson's disease.

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12 December 2020

Enzymic studies on the animal and intestinal bacterial metabolism of geniposide

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12 December 2020

10.1007/S40263-016-0369-9

Identifiers

DOI

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7 September 2017

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