The Protective Role of Phenolic Compounds Against Doxorubicin-induced Cardiotoxicity: A Comprehensive Review (Q38875916)

7 September 2017

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title

The Protective Role of Phenolic Compounds Against Doxorubicin-induced Cardiotoxicity: A Comprehensive Review (English)

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7 September 2017

3

Amirhossein Sahebkar

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7 September 2017

author name string

Kamal Razavi-Azarkhiavi

1

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7 September 2017

Milad Iranshahy

2

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7 September 2017

Kobra Shirani

4

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7 September 2017

Gholamreza Karimi

5

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7 September 2017

publication date

24 June 2016

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7 September 2017

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7 September 2017

volume

68

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7 September 2017

issue

6

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7 September 2017

page(s)

892-917

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Doxorubicin-induced cardiotoxicity: from bioenergetic failure and cell death to cardiomyopathy.

7 September 2017

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Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice

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Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes

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Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways

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Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation

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Doxorubicin coupled to penetratin promotes apoptosis in CHO cells by a mechanism involving c-Jun NH2-terminal kinase.

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Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes

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Protective role of antioxidant vitamin E and catechin on idarubicin-induced cardiotoxicity in rats

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Prevention of doxorubicin induced cardiotoxicity by catechin

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Catechin and proanthocyanidin B4 from grape seeds prevent doxorubicin-induced toxicity in cardiomyocytes

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Chrysin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells via suppression of nuclear factor-kappaB.

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Effect of chrysin on hepatoprotective and antioxidant status in D-galactosamine-induced hepatitis in rats

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Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

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Discovery of chrysoeriol, a PI3K-AKT-mTOR pathway inhibitor with potent antitumor activity against human multiple myeloma cells in vitro

21 January 2018

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Antioxidant effects of the VO(IV) hesperidin complex and its role in cancer chemoprevention.

21 January 2018

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Evaluation of antioxidant activity of hesperidin and its protective effect on H2O2 induced oxidative damage on pBR322 DNA and RBC cellular membrane

21 January 2018

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Flavanone absorption after naringin, hesperidin, and citrus administration

21 January 2018

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Antiallergic activity of hesperidin is activated by intestinal microflora

21 January 2018

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Cardioprotective Effects of Hesperetin against Doxorubicin-Induced Oxidative Stress and DNA Damage in Rat

21 January 2018

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Effects of solid dispersion and self-emulsifying formulations on the solubility, dissolution, permeability and pharmacokinetics of isorhamnetin, quercetin and kaempferol in total flavones of Hippophae rhamnoides L.

21 January 2018

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Isorhamnetin protects against doxorubicin-induced cardiotoxicity in vivo and in vitro

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Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species.

21 January 2018

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Comparative evaluation of cytotoxicity and antioxidative activity of 20 flavonoids

21 January 2018

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Induction of apoptosis in human lymphoblastoid cells by kaempferol 3-O-β-isorhamninoside and rhamnocitrin 3-O-β-isorhamninoside from Rhamnus alaternus L. (Rhamnaceae)

21 January 2018

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Kaempferol Attenuates 4-Hydroxynonenal-Induced Apoptosis in PC12 Cells by Directly Inhibiting NADPH Oxidase

21 January 2018

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Kaempferol modulates pro-inflammatory NF-kappaB activation by suppressing advanced glycation endproducts-induced NADPH oxidase

21 January 2018

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The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinase pathways.

21 January 2018

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Monohydroxyethylrutoside as protector against chronic doxorubicin-induced cardiotoxicity

21 January 2018

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The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro

21 January 2018

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Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice

21 January 2018

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A phase I study of monohydroxyethylrutoside in healthy volunteers

21 January 2018

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The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study

21 January 2018

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Effects of flavonoids on immune and inflammatory cell functions

21 January 2018

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Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study

21 January 2018

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https://api.crossref.org/works/10.1080/01635581.2016.1187280

Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits

21 January 2018

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Alleviation of iron induced oxidative stress by the grape fruit flavanone naringin in vitro

21 January 2018

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Combined effects of p-coumaric acid and naringenin against doxorubicin-induced cardiotoxicity in rats

21 January 2018

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Protective effects of naringenin-7-O-glucoside on doxorubicin-induced apoptosis in H9C2 cells

21 January 2018

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Naringenin-7-O-glucoside protects against doxorubicin-induced toxicity in H9c2 cardiomyocytes by induction of endogenous antioxidant enzymes

21 January 2018

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Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver

21 January 2018

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Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

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Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytes

21 January 2018

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https://api.crossref.org/works/10.1080/01635581.2016.1187280

Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes.

21 January 2018

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https://api.crossref.org/works/10.1080/01635581.2016.1187280

Quercetin-induced cardioprotection against doxorubicin cytotoxicity

21 January 2018

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Quercetin augments the protective effect of losartan against chronic doxorubicin cardiotoxicity in rats.

21 January 2018

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BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

21 January 2018

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The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

21 January 2018

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Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression.

21 January 2018

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Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis

21 January 2018

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21 January 2018

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Targeting cell signaling and apoptotic pathways by luteolin: cardioprotective role in rat cardiomyocytes following ischemia/reperfusion

21 January 2018

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Anti-diabetic properties of flavonoid compounds isolated from Hyphaene thebaica epicarp on alloxan induced diabetic rats.

21 January 2018

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Protective effect of flavonoids on doxorubicin-induced cardiotoxicity

21 January 2018

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Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Recent advances in pharmacotherapy for hypertriglyceridemia

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Curcumin attenuation of acute adriamycin myocardial toxicity in rats

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21 January 2018

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Influence of silymarin and its flavonolignans on doxorubicin-iron induced lipid peroxidation in rat heart microsomes and mitochondria in comparison with quercetin

21 January 2018

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Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP-2 uvrA.

21 January 2018

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21 January 2018

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Silymarin prevents adriamycin-induced cardiotoxicity and nephrotoxicity in rats

21 January 2018

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Mechanisms underlying the protective effect of eugenol in rats with acute doxorubicin cardiotoxicity

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21 January 2018

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Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.

21 January 2018

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Salidroside improves doxorubicin-induced cardiac dysfunction by suppression of excessive oxidative stress and cardiomyocyte apoptosis

21 January 2018

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Hydroxytyrosol: from laboratory investigations to future clinical trials.

21 January 2018

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Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer.

21 January 2018

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Metabonomic identification of novel biomarkers in doxorubicin cardiotoxicity and protective effect of the natural antioxidant oleuropein

21 January 2018

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Targeting AMPK for cardiac protection: Opportunities and challenges

21 January 2018

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Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

21 January 2018

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Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism.

21 January 2018

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Resveratrol: review on therapeutic potential and recent advances in drug delivery.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury

21 January 2018

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Resveratrol is not a direct activator of SIRT1 enzyme activity

21 January 2018

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The role of autophagy in doxorubicin-induced cardiotoxicity

21 January 2018

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https://api.crossref.org/works/10.1080/01635581.2016.1187280

Resveratrol attenuates doxorubicin-induced cardiomyocyte death via inhibition of p70 S6 kinase 1-mediated autophagy

21 January 2018

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Metabolism and bioavailability of trans-resveratrol.

21 January 2018

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https://api.crossref.org/works/10.1080/01635581.2016.1187280

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in lymphoma nude mice by heme oxygenase-1 induction

21 January 2018

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Protective effect of resveratrol against doxorubicin-induced cardiac toxicity and fibrosis in male experimental rats

21 January 2018

1 reference

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Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: role for heme oxygenase-1 down-modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/01635581.2016.1187280

Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy

21 January 2018

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Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin

21 January 2018

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Polymeric micellar co-delivery of resveratrol and curcumin to mitigate in vitro doxorubicin-induced cardiotoxicity.

21 January 2018

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Protective effect of tetrahydroxystilbene glucoside on cardiotoxicity induced by doxorubicin in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/01635581.2016.1187280

Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/01635581.2016.1187280

Antioxidant, lipid lowering, and membrane stabilization effect of sesamol against doxorubicin-induced cardiomyopathy in experimental rats.

21 January 2018

1 reference

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6-gingerol ameliorated doxorubicin-induced cardiotoxicity: role of nuclear factor kappa B and protein glycation

21 January 2018

1 reference

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Mitochondrial reactive oxygen species and Ca2 signaling

21 January 2018

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Mechanisms of Ca2 overload induced by extracellular H2O2 in quiescent isolated rat cardiomyocytes

21 January 2018

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Endothelin-1 regulates cardiac L-type calcium channels via NAD(P)H oxidase-derived superoxide

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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10.1080/01635581.2016.1187280

21 January 2018

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DOI

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7 September 2017

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