Histone deacetylase inhibitor valproic acid promotes the induction of pluripotency in mouse fibroblasts by suppressing reprogramming-induced senescence stress (Q38860033)

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English	Histone deacetylase inhibitor valproic acid promotes the induction of pluripotency in mouse fibroblasts by suppressing reprogramming-induced senescence stress	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 September 2017

Histone deacetylase inhibitor valproic acid promotes the induction of pluripotency in mouse fibroblasts by suppressing reprogramming-induced senescence stress (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

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Jiuwei Cui

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7 September 2017

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Yingying Zhai

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7 September 2017

Xi Chen

2

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7 September 2017

Dehai Yu

3

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7 September 2017

Tao Li

4

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7 September 2017

Guanjun Wang

6

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7 September 2017

Ji-Fan Hu

7

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7 September 2017

Wei Li

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7 September 2017

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22 June 2015

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7 September 2017

Experimental Cell Research

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7 September 2017

337

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7 September 2017

1

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7 September 2017

61-67

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7 September 2017

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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https://api.crossref.org/works/10.1016/J.YEXCR.2015.06.003

7 January 2021

Pluripotent stem cells and disease modeling

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7 January 2021

Reprogramming of human somatic cells to pluripotency with defined factors

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7 January 2021

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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Induced pluripotent stem cells and senescence: learning the biology to improve the technology

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Chromatin looping is needed for iPSC induction

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A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

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7 January 2021

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

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Vitamin C enhances the generation of mouse and human induced pluripotent stem cells

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Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

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A chemical platform for improved induction of human iPSCs

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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Histone deacetylase is a target of valproic acid-mediated cellular differentiation

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7 January 2021

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

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Valproic acid affects the engraftment of TPO-expanded cord blood cells in NOD/SCID mice

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Histone deacetylase inhibitor valproic acid enhances the cytokine-induced expansion of human hematopoietic stem cells.

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Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells

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New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet?

1 reference

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7 January 2021

Senescence impairs successful reprogramming to pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016/J.YEXCR.2015.06.003

7 January 2021

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

1 reference

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7 January 2021

Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming.

1 reference

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Tissue-Specific Imprinting of the Mouse Insulin-Like Growth Factor II Receptor Gene Correlates with Differential Allele-Specific DNA Methylation

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Genomic Deletion of an Imprint Maintenance Element Abolishes Imprinting of Both Insulin-like Growth Factor II andH19

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Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway

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Transient in vitro epigenetic reprogramming of skin fibroblasts into multipotent cells

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Role of p38MAPK and oxidative stress in copper-induced senescence

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Copper ability to induce premature senescence in human fibroblasts.

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Copper induces cellular senescence in human glioblastoma multiforme cells through downregulation of Bmi-1.

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Essentiality and toxicity in copper health risk assessment: overview, update and regulatory considerations

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Adipose-derived stem cells retain their regenerative potential after methotrexate treatment.

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Enhanced therapeutic efficacy by simultaneously targeting two genetic defects in tumors

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Potentiation of tumor radiotherapy by a radiation‐inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts

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A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

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Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells

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Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus.

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Promoter histone H3K27 methylation in the control of IGF2 imprinting in human tumor cell lines

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The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences

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Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation

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Valproic acid inhibits the proliferation of cancer cells by re-expressing cyclin D2.

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Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells

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Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia

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Identifiers

10.1016/J.YEXCR.2015.06.003

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

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