Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity (Q38856439)

7 September 2017

title

Grafting segments from the extracellular surface of CCR5 onto a bacteriorhodopsin transmembrane scaffold confers HIV-1 coreceptor activity (English)

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7 September 2017

main subject

transmembrane protein

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author name string

Najmoutin G Abdulaev

1

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7 September 2017

Timothy T Strassmaier

2

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7 September 2017

Tony Ngo

3

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7 September 2017

Ruiwu Chen

4

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7 September 2017

Hartmut Luecke

5

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7 September 2017

Daniel D Oprian

6

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7 September 2017

Kevin D Ridge

7

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7 September 2017

publication date

1 April 2002

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7 September 2017

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7 September 2017

volume

10

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7 September 2017

issue

4

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7 September 2017

page(s)

515-525

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

7 September 2017

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Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

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HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.

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7 January 2021

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

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7 January 2021

Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity

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7 January 2021

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

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7 January 2021

HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor

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7 January 2021

CC chemokine receptor 5-mediated signaling and HIV-1 Co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion

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7 January 2021

CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains

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7 January 2021

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

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7 January 2021

Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

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7 January 2021

Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry

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7 January 2021

A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5

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7 January 2021

Alanine Substitutions of Polar and Nonpolar Residues in the Amino-Terminal Domain of CCR5 Differently Impair Entry of Macrophage- and Dualtropic Isolates of Human Immunodeficiency Virus Type 1

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7 January 2021

CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domains

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7 January 2021

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

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7 January 2021

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

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7 January 2021

The second extracellular loop of CCR5 is the major determinant of ligand specificity.

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7 January 2021

Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity

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7 January 2021

Functionally discrete mimics of light-activated rhodopsin identified through expression of soluble cytoplasmic domains

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7 January 2021

Progress toward an explicit mechanistic model for the light-driven pump, bacteriorhodopsin

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7 January 2021

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

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7 January 2021

X-ray Structure of Bacteriorhodopsin at 2.5 Angstroms from Microcrystals Grown in Lipidic Cubic Phases

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7 January 2021

Proton transfer pathways in bacteriorhodopsin at 2.3 angstrom resolution

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7 January 2021

Lipid patches in membrane protein oligomers: crystal structure of the bacteriorhodopsin-lipid complex

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7 January 2021

An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium

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7 January 2021

Gene replacement in Halobacterium halobium and expression of bacteriorhodopsin mutants

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7 January 2021

Conformations of the rhodopsin third cytoplasmic loop grafted onto bacteriorhodopsin

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7 January 2021

Structure of bacteriorhodopsin at 1.55 A resolution

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7 January 2021

Expression of bacteriorhodopsin in Sf9 and COS-1 cells.

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7 January 2021

Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor

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7 January 2021

Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120

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7 January 2021

A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry

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7 January 2021

Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin.

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7 January 2021

Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics

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7 January 2021

Helical membrane protein folding, stability, and evolution

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7 January 2021

Role of the intradiscal domain in rhodopsin assembly and function

1 reference

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7 January 2021

Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled

1 reference

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7 January 2021

Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve

1 reference

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7 January 2021

Expression of a synthetic bovine rhodopsin gene in monkey kidney cells

1 reference

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7 January 2021

Monoclonal antibodies to rhodopsin: characterization, cross-reactivity, and application as structural probes

1 reference

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7 January 2021

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1 reference

https://api.crossref.org/works/10.1016/S0969-2126(02)00752-9

7 January 2021

Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements

1 reference

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7 January 2021

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

1 reference

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7 January 2021

Crystal structure of an HIV-binding recombinant fragment of human CD4.

1 reference

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7 January 2021

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

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7 January 2021

10.1016/S0969-2126(02)00752-9

Identifiers

DOI

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release_4vvlgwb3xvdb5knhyntxdw2rmm

7 September 2017

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24 November 2022

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