Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection. (Q38845065)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26256479 AND SRC:MED&resulttype=core&format=json

21 February 2020

title

Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection (English)

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21 February 2020

5

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21 February 2020

4

Drew Weissman

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21 February 2020

3

Veronica M Holmes

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21 February 2020

author name string

Laura M Castellano

series ordinal

1

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21 February 2020

Stephen M Bart

series ordinal

2

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21 February 2020

language of work or name

1 reference

6 August 2015

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21 February 2020

published in

Chemistry and Biology

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21 February 2020

volume

22

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21 February 2020

issue

8

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21 February 2020

page(s)

1074-1086

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Engineering enhanced protein disaggregases for neurodegenerative disease

21 February 2020

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9 September 2017

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Hsp104 drives "protein-only" positive selection of Sup35 prion strains encoding strong [PSI( )].

9 September 2017

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9 September 2017

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Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide

9 September 2017

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Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection

9 September 2017

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Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection

9 September 2017

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The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system

9 September 2017

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The elusive middle domain of Hsp104 and ClpB: location and function.

9 September 2017

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Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

9 September 2017

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The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency.

9 September 2017

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Applying Hsp104 to protein-misfolding disorders.

9 September 2017

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The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection

9 September 2017

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9 September 2017

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9 September 2017

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Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions

9 September 2017

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Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease

9 September 2017

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Hsp104: a weapon to combat diverse neurodegenerative disorders.

9 September 2017

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Semen-derived amyloid fibrils drastically enhance HIV infection

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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14 September 2017

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14 September 2017

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25 September 2017

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Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events

25 September 2017

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Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding

17 June 2018

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Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities

17 June 2018

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Characterization and Hsp104-induced artificial clearance of familial ALS-related SOD1 aggregates

17 June 2018

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Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses.

22 August 2018

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A tightly regulated molecular toggle controls AAA disaggregase.

22 August 2018

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Mechanism of fibril formation by a 39-residue peptide (PAPf39) from human prostatic acidic phosphatase

22 August 2018

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Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

22 August 2018

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The amino-terminal domain of ClpB supports binding to strongly aggregated proteins

22 August 2018

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22 August 2018

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Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

22 August 2018

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Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein

22 August 2018

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10.1016/J.CHEMBIOL.2015.07.007

22 August 2018

Identifiers

DOI

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21 February 2020

1 reference

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21 February 2020

PubMed publication ID

26256479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26256479 AND SRC:MED&resulttype=core&format=json