Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches (Q38844375)

1 July 2019

review article

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title

Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches (English)

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1 July 2019

Robert Dantzer

1

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publication date

1 January 2017

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1 July 2019

Current topics in behavioral neurosciences

published in

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1 July 2019

volume

31

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1 July 2019

page(s)

117-138

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1 July 2019

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

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NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice

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Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?

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Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

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Behavioral Deficits Are Accompanied by Immunological and Neurochemical Changes in a Mouse Model for Neuropsychiatric Lupus (NP-SLE).

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CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway

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Inflamm-aging. An evolutionary perspective on immunosenescence

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Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system.

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Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

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A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

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Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions

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Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

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Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

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12 December 2020

NF-kappa B activation contributes to indoleamine dioxygenase transcriptional synergy induced by IFN-gamma and tumor necrosis factor-alpha

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Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism

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High-affinity uptake of L-kynurenine by a Na -independent transporter of neutral amino acids in astrocytes

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Interaction of kynurenine and its metabolites with tryptamine, serotonin and its precursors and oxotremorine

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Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice

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12 December 2020

Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids

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12 December 2020

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes

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12 December 2020

Species Heterogeneity Between Gerbils and Rats: Quinolinate Production by Microglia and Astrocytes and Accumulations in Response to Ischemic Brain Injury and Systemic Immune Activation

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Identifiers

DOI

10.1007/7854_2016_6

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1 July 2019

PMC publication ID

6585430

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1 July 2019

PubMed publication ID

27225497

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1 July 2019