Chemistry, Pharmacology and Health Benefits of Anthocyanins. (Q38843382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27221033 AND SRC:MED&resulttype=core&format=json

2 April 2020

review article

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title

Chemistry, Pharmacology and Health Benefits of Anthocyanins (English)

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2 April 2020

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1

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2 April 2020

Davide Barreca

series ordinal

2

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2 April 2020

Ersilia Bellocco

series ordinal

3

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2 April 2020

author name string

Domenico Trombetta

series ordinal

4

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2 April 2020

publication date

25 May 2016

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2 April 2020

published in

Phytotherapy Research

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2 April 2020

volume

30

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2 April 2020

issue

8

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2 April 2020

page(s)

1265-1286

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Fractionation of blue wheat anthocyanin compounds and their contribution to antioxidant properties

2 April 2020

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Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidants.

21 January 2018

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Quantification and characterisation of cyclo-oxygenase and lipid peroxidation inhibitory anthocyanins in fruits of Amelanchier

21 January 2018

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Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice.

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Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats

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Carbohydrate and fiber recommendations for individuals with diabetes: a quantitative assessment and meta-analysis of the evidence

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The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides

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Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti-inflammatory effects of pomegranate juice in hypertensive subjects.

21 January 2018

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In vitro metabolism of anthocyanins by human gut microflora

21 January 2018

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Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula

21 January 2018

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First evidence of C- and O-glycosyl flavone in blood orange (Citrus sinensis (L.) Osbeck) juice and their influence on antioxidant properties.

21 January 2018

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Interaction of anthocyanins with drug-metabolizing and antioxidant enzymes.

21 January 2018

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Effect of cyanidin 3-O-beta-glucopyranoside on hepatic stellate cell proliferation and collagen synthesis induced by oxidative stress

21 January 2018

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Tree nut phytochemicals: composition, antioxidant capacity, bioactivity, impact factors. A systematic review of almonds, Brazils, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts.

21 January 2018

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The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition

21 January 2018

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Mechanisms linking diet and colorectal cancer: the possible role of insulin resistance

21 January 2018

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Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials

21 January 2018

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Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells

21 January 2018

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Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin

21 January 2018

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Inhibitory Effect of Delphinidin on Monocyte–Endothelial Cell Adhesion Induced by Oxidized Low-Density Lipoprotein via ROS/p38MAPK/NF-κB Pathway

21 January 2018

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Effect of cyanidin-3-O-glucoside on UVB-induced response in human keratinocytes.

21 January 2018

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Anthocyans from fruits and vegetables--does bright colour signal cancer chemopreventive activity?

21 January 2018

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21 January 2018

Inflammation and cancer

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Dietary phenolics: chemistry, bioavailability and effects on health

21 January 2018

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Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells.

21 January 2018

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Anthocyanins and their metabolites are weak inhibitors of cytochrome P450 3A4.

21 January 2018

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Scientific Opinion on the re-evaluation of anthocyanins (E 163) as a food additive

21 January 2018

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Consumption of fruit and berries is inversely associated with carotid atherosclerosis in elderly men.

21 January 2018

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Involvement of cyclin-dependent pathway in the inhibitory effect of delphinidin on angiogenesis

21 January 2018

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Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans

21 January 2018

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A new approach on the gastric absorption of anthocyanins

21 January 2018

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Identification of Cabernet Sauvignon anthocyanin gut microflora metabolites

21 January 2018

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Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release

21 January 2018

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Enhanced Anthocyanin Extraction from Red Cabbage Using Pulsed Electric Field Processing

21 January 2018

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Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection

21 January 2018

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Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma

21 January 2018

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Photoprotective potential of strawberry (Fragaria × ananassa) extract against UV-A irradiation damage on human fibroblasts.

21 January 2018

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Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy.

21 January 2018

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A multidrug resistance-associated protein involved in anthocyanin transport in Zea mays

21 January 2018

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Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats

21 January 2018

1 reference

Cyanidin-3-O-beta-glucopyranoside, a natural free-radical scavenger against aflatoxin B1- and ochratoxin A-induced cell damage in a human hepatoma cell line (Hep G2) and a human colonic adenocarcinoma cell line (CaCo-2).

21 January 2018

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Correlation of antioxidants with lipid peroxidation and lipid profile in patients suffering from coronary artery disease.

21 January 2018

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Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?

21 January 2018

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Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study

21 January 2018

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Anthocyanins: natural colorants with health-promoting properties.

21 January 2018

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Stability of black raspberry anthocyanins in the digestive tract lumen and transport efficiency into gastric and small intestinal tissues in the rat.

21 January 2018

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Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved

21 January 2018

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Potential mechanisms of cancer chemoprevention by anthocyanins

21 January 2018

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Black raspberry extracts inhibit benzo(a)pyrene diol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway

21 January 2018

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Extended glucuronidation is another major path of cyanidin 3-O-beta-D-glucopyranoside metabolism in rats

21 January 2018

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A Systematic Review on the Health Effects of Plums (Prunus domestica and Prunus salicina).

21 January 2018

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Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth.

21 January 2018

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Characterization of anthocyanin-rich waste from purple corncobs (Zea mays L.) and its application to color milk.

21 January 2018

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Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model

21 January 2018

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Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation

21 January 2018

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Antioxidant activity of anthocyanins and their aglycons

21 January 2018

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Anthocyanin Absorption and Metabolism by Human Intestinal Caco-2 Cells--A Review

21 January 2018

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Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human fibroblasts by anthocyanidins

21 January 2018

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Anthocyanin metabolites in human urine and serum

21 January 2018

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Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans

21 January 2018

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Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora

21 January 2018

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Improved lipid profile in hyperlipidemic patients taking Vaccinium arctostaphylos fruit hydroalcoholic extract: a randomized double-blind placebo-controlled clinical trial

21 January 2018

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Inhibitory effects of fruit juices on CYP3A activity

21 January 2018

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Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity

21 January 2018

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Commentary: could abstinence from alcohol be hazardous to your health?

21 January 2018

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Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats.

21 January 2018

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Analysis and biological activities of anthocyanins

21 January 2018

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Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment

21 January 2018

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α-glucosidase inhibitors from plants: A natural approach to treat diabetes

21 January 2018

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Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7.

21 January 2018

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Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats.

21 January 2018

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Interindividual differences in phytochemical metabolism and disposition

21 January 2018

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The Arabidopsis MATE transporter TT12 acts as a vacuolar flavonoid/H -antiporter active in proanthocyanidin-accumulating cells of the seed coat

21 January 2018

1 reference

Inhibition of malonaldehyde formation in oxidized calf thymus DNA with synthetic and natural antioxidants

21 January 2018

1 reference

Caffeoylsophorose, a new natural alpha-glucosidase inhibitor, from red vinegar by fermented purple-fleshed sweet potato

21 January 2018

1 reference

Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the alpha-glucosidase inhibitory action

21 January 2018

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alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins

21 January 2018

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Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats

21 January 2018

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Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms

21 January 2018

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Delphinidin-3-rutinoside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway

21 January 2018

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Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects

21 January 2018

1 reference

The bioavailability and absorption of anthocyanins: towards a better understanding

21 January 2018

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Xenobiotic metabolism and berry flavonoid transport across the blood-brain barrier

21 January 2018

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Anthocyanins are bioavailable in humans following an acute dose of cranberry juice

21 January 2018

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Cultivars of apple fruits that are not marketed with potential for anthocyanin production

21 January 2018

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Urinary excretion of cyanidin glycosides

21 January 2018

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Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues

21 January 2018

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Anthocyanins as a potential therapy for diabetic retinopathy

21 January 2018

1 reference

Antibacterial activity directed isolation of compounds from Punica granatum

21 January 2018

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Identification of a cranberry juice product that inhibits enteric CYP3A-mediated first-pass metabolism in humans.

21 January 2018

1 reference

Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens.

21 January 2018

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Anthocyanin composition and antioxidant activity of the Crowberry (Empetrum nigrum) and other berries

21 January 2018

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Effects of diet composition on mutagenic activity in urine

21 January 2018

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Two-year randomized, placebo-controlled study of black currant anthocyanins on visual field in glaucoma

21 January 2018

1 reference

A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer

21 January 2018

1 reference

Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer

21 January 2018

1 reference

Bioavailability of flavonoids: a review of their membrane transport and the function of bilitranslocase in animal and plant organisms.

21 January 2018

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The stomach as a site for anthocyanins absorption from food

21 January 2018

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Urinary metabolites as biomarkers of polyphenol intake in humans: a systematic review.

21 January 2018

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Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract

21 January 2018

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Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities

21 January 2018

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Whole berries versus berry anthocyanins: interactions with dietary fat levels in the C57BL/6J mouse model of obesity

21 January 2018

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Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet

21 January 2018

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Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats

21 January 2018

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Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects

21 January 2018

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Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins

21 January 2018

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Potential risks resulting from fruit/vegetable-drug interactions: effects on drug-metabolizing enzymes and drug transporters.

21 January 2018

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Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation

21 January 2018

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Action of pelargonidin on hyperglycemia and oxidative damage in diabetic rats: implication for glycation-induced hemoglobin modification

21 January 2018

1 reference

Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-beta-d-glucoside.

21 January 2018

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Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice

21 January 2018

1 reference

Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury.

21 January 2018

1 reference

Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries

21 January 2018

1 reference

Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials

21 January 2018

1 reference

Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure

21 January 2018

1 reference

Strawberry intake, lipids, C-reactive protein, and the risk of cardiovascular disease in women

21 January 2018

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Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells

21 January 2018

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Anthocyanins induce the activation of phase II enzymes through the antioxidant response element pathway against oxidative stress-induced apoptosis

21 January 2018

1 reference

Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats

21 January 2018

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Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus

21 January 2018

1 reference

Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration

21 January 2018

1 reference

Inhibition of rat mammary tumorigenesis by concord grape juice constituents.

21 January 2018

1 reference

Anthocyanin-rich grape extract blocks breast cell DNA damage.

21 January 2018

1 reference

Health effects of Vaccinium myrtillus L.: evaluation of efficacy and technological strategies for preservation of active ingredients.

21 January 2018

1 reference

Heme oxygenase induction by cyanidin-3-O-beta-glucoside in cultured human endothelial cells

21 January 2018

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The impact of fruit flavonoids on memory and cognition

21 January 2018

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Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and phase II enzymes.

21 January 2018

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Alcoholic beverage preference, 29-year mortality, and quality of life in men in old age.

21 January 2018

1 reference

Long-term wine consumption is related to cardiovascular mortality and life expectancy independently of moderate alcohol intake: the Zutphen Study

21 January 2018

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Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice.

21 January 2018

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Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain

21 January 2018

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Protective effects of cyanidin-3-O-beta-glucopyranoside against UVA-induced oxidative stress in human keratinocytes.

21 January 2018

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Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?

21 January 2018

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Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins.

21 January 2018

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Microarray profiling of gene expression in human adipocytes in response to anthocyanins

21 January 2018

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Dietary anthocyanin‐rich plants: Biochemical basis and recent progress in health benefits studies

21 January 2018

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Cranberry juice suppressed the diclofenac metabolism by human liver microsomes, but not in healthy human subjects

21 January 2018

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Dietary anthocyanins as nutritional therapy for nonalcoholic fatty liver disease

21 January 2018

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Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model

21 January 2018

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Efficacy and safety of pomegranate medicinal products for cancer.

21 January 2018

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Anthocyanins in cardiovascular disease

21 January 2018

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Systematic Review of Anthocyanins and Markers of Cardiovascular Disease

21 January 2018

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Cyanidin-3-O-β-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein E-deficient mice

21 January 2018

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Anthocyanins and their role in cancer prevention

21 January 2018

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Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies

21 January 2018

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21 January 2018

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An anthocyanin/polyphenolic-rich fruit juice reduces oxidative DNA damage and increases glutathione level in healthy probands

21 January 2018

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Functional foods for health promotion: state-of-the-science on dietary flavonoids. Extended abstracts from the 12th Annual Conference on Functional Foods for Health Promotion, April 2009.

21 January 2018

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Anthocyanin stability and recovery: implications for the analysis of clinical and experimental samples

21 January 2018

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Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption

21 January 2018

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Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

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Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment

21 January 2018

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Cyanidin-3-glucoside regulates phosphorylation of endothelial nitric oxide synthase

21 January 2018

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Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon).

21 January 2018

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Food Matrix Affecting Anthocyanin Bioavailability: Review

21 January 2018

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Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis

21 January 2018

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Antimutagenicity of deacylated anthocyanins in purple-fleshed sweetpotato

21 January 2018

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Berry anthocyanins as novel antioxidants in human health and disease prevention

21 January 2018

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Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort

21 January 2018

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Estimation of the intake of anthocyanidins and their food sources in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

21 January 2018

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New insight into the structures and formation of anthocyanic vacuolar inclusions in flower petals

21 January 2018

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Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties

21 January 2018

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Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumorigenic colonic cell growth.

21 January 2018

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Flavonoids and Prostate Cancer Risk: A Study in Italy

21 January 2018

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Wine consumption and risk of cardiovascular events after myocardial infarction: Results from the GISSI-Prevenzione trial

21 January 2018

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Flavonoids and the Risk of Oral and Pharyngeal Cancer: A Case-Control Study from Italy

21 January 2018

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Effect of vaccinium myrtillus anthocyanosides on ischaemia reperfusion injury in hamster cheek pouch microcirculation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PTR.5642

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27221033 AND SRC:MED&resulttype=core&format=json

2 April 2020

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