Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding (Q38843283)

6 September 2017

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title

Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding (English)

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6 September 2017

Min Lu

1

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6 September 2017

Mary R Muers

series ordinal

2

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6 September 2017

Xin Lu

series ordinal

3

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6 September 2017

publication date

25 May 2016

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Nature Reviews Molecular Cell Biology

6 September 2017

published in

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6 September 2017

volume

17

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6 September 2017

issue

8

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6 September 2017

page(s)

523-532

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A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

6 September 2017

cites work

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Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

31 March 2020

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Functional interaction of beta-catenin with the transcription factor LEF-1

31 March 2020

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

31 March 2020

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

31 March 2020

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Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

31 March 2020

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Actin dynamics control SRF activity by regulation of its coactivator MAL

31 March 2020

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Potentiation of serum response factor activity by a family of myocardin-related transcription factors

31 March 2020

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Nuclear transport of the serum response factor coactivator MRTF-A is downregulated at tensional homeostasis

31 March 2020

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Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

31 March 2020

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The role of the MRTF-A/SRF pathway in ocular fibrosis

31 March 2020

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Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator

31 March 2020

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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

31 March 2020

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Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

31 March 2020

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RelA/NF-kappaB transcription factor associates with alpha-actinin-4.

31 March 2020

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α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function

31 March 2020

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Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation

31 March 2020

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Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

31 March 2020

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Nesprins LINC the nucleus and cytoskeleton

31 March 2020

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Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

31 March 2020

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Focal adhesion kinase: in command and control of cell motility

31 March 2020

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Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

31 March 2020

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Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2.

31 March 2020

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Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.

31 March 2020

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Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

31 March 2020

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Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity

31 March 2020

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Mechanical loading activates β-catenin signaling in periodontal ligament cells

31 March 2020

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β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells

31 March 2020

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Extracellular matrix stiffness dictates Wnt expression through integrin pathway

31 March 2020

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Adhesion molecule signalling: not always a sticky business.

31 March 2020

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Beyond β-catenin: prospects for a larger catenin network in the nucleus

31 March 2020

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

31 March 2020

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Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

31 March 2020

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Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

31 March 2020

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Role of YAP/TAZ in mechanotransduction

31 March 2020

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Hippo pathway regulation by cell morphology and stress fibers.

31 March 2020

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

31 March 2020

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A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

31 March 2020

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YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

31 March 2020

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Mutual regulation between Hippo signaling and actin cytoskeleton

31 March 2020

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The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

31 March 2020

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Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

31 March 2020

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PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

31 March 2020

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A regulatory circuit controlling Itch-mediated p73 degradation by Runx.

31 March 2020

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The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation

31 March 2020

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The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules

31 March 2020

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A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein

31 March 2020

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Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease

31 March 2020

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FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner

31 March 2020

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Interaction of p38 and Sp1 in a mechanical force-induced, beta 1 integrin-mediated transcriptional circuit that regulates the actin-binding protein filamin-A

31 March 2020

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Filamin associates with Smads and regulates transforming growth factor-beta signaling

31 March 2020

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Classical nuclear localization signals: definition, function, and interaction with importin alpha

31 March 2020

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A new role for nuclear transport factor 2 and Ran: nuclear import of CapG

31 March 2020

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Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

31 March 2020

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A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway

31 March 2020

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Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.

31 March 2020

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An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A

31 March 2020

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Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP

31 March 2020

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Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling

31 March 2020

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Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

31 March 2020

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The Notch signalling system: recent insights into the complexity of a conserved pathway

31 March 2020

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Notch signalling in solid tumours: a little bit of everything but not all the time

31 March 2020

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ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth

31 March 2020

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The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.

31 March 2020

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A transcription co-factor integrates cell adhesion and motility with the p53 response.

31 March 2020

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A novel cofactor for p300 that regulates the p53 response

31 March 2020

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Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

31 March 2020

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Transcriptional co-repressor function of the hippo pathway transducers YAP and TAZ.

31 March 2020

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Notch signaling: cell fate control and signal integration in development

31 March 2020

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Wnt/beta-catenin signaling: components, mechanisms, and diseases

31 March 2020

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RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development

31 March 2020

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Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

31 March 2020

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WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway.

31 March 2020

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Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation.

31 March 2020

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Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

31 March 2020

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31 March 2020

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Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors

31 March 2020

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The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy

31 March 2020

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The mutational landscape of head and neck squamous cell carcinoma

31 March 2020

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Comprehensive genomic characterization of squamous cell lung cancers

31 March 2020

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

31 March 2020

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Mutations in TRPV4 cause an inherited arthropathy of hands and feet.

31 March 2020

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Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia

31 March 2020

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Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

31 March 2020

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Channelopathies converge on TRPV4

31 March 2020

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Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat.

31 March 2020

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Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.

31 March 2020

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TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes

31 March 2020

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Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity

31 March 2020

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Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation

31 March 2020

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Restriction of intestinal stem cell expansion and the regenerative response by YAP.

31 March 2020

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Role of TAZ as mediator of Wnt signaling

31 March 2020

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β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

31 March 2020

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Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

31 March 2020

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PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ

31 March 2020

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ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells

31 March 2020

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ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.

31 March 2020

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A gp130-Src-YAP module links inflammation to epithelial regeneration

31 March 2020

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Hippo pathway activity influences liver cell fate

31 March 2020

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Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

31 March 2020

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Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

31 March 2020

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β-Catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial–myofibroblast transition

31 March 2020

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Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition

31 March 2020

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Nuclear FAK: a new mode of gene regulation from cellular adhesions

31 March 2020

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p53-cofactor JMY is a multifunctional actin nucleation factor

31 March 2020

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Kindlin-2 mediates activation of TGF-β/Smad signaling and renal fibrosis

31 March 2020

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Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

31 March 2020

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ASPP proteins specifically stimulate the apoptotic function of p53

31 March 2020

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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

31 March 2020

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Aspp1 Preserves Hematopoietic Stem Cell Pool Integrity and Prevents Malignant Transformation.

31 March 2020

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WNT signalling pathways as therapeutic targets in cancer

31 March 2020

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The Actin-binding Protein, Actinin Alpha 4 (ACTN4), Is a Nuclear Receptor Coactivator that Promotes Proliferation of MCF-7 Breast Cancer Cells

31 March 2020

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Small leucine zipper protein (sLZIP) negatively regulates skeletal muscle differentiation via interaction with α-actinin-4.

31 March 2020

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Evolution of the gelsolin family of actin-binding proteins as novel transcriptional coactivators.

31 March 2020

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Nuclear actin-binding proteins as modulators of gene transcription

31 March 2020

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Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus

31 March 2020

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UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome

31 March 2020

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CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway

31 March 2020

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12 December 2020

Identification and purification of a polypeptide that binds to the c-fos serum response element

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12 December 2020

E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation

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12 December 2020

The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation

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12 December 2020

Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction

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12 December 2020

Identifiers

DOI

10.1038/NRM.2016.41

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Dimensions Publication ID

6 September 2017

1036283483

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