Management of iron overload in hemoglobinopathies: what is the appropriate target iron level? (Q38836181)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

review article

1 reference

title

Management of iron overload in hemoglobinopathies: what is the appropriate target iron level? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Susan Carson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

John C Wood

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

Vasilios Berdoukas

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

language of work or name

English

0 references

publication date

1 March 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

Annals of the New York Academy of Sciences

1 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

volume

1368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

95-106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

Results of long-term iron-chelating therapy

1 April 2020

cites work

1 reference

Cost effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassaemia patients: US healthcare system perspective.

21 January 2018

1 reference

Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance

21 January 2018

1 reference

Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major

21 January 2018

1 reference

Decreased cancer risk after iron reduction in patients with peripheral arterial disease: results from a randomized trial

21 January 2018

1 reference

Impact of serum ferritin level on hepatocarcinogenesis in chronic hepatitis C patients

21 January 2018

1 reference

Incidence of hepatocellular carcinoma reduced by phlebotomy treatment in patients with chronic hepatitis C.

21 January 2018

1 reference

Evolution of iron overload in patients with low-risk myelodysplastic syndrome: iron chelation therapy and organ complications

21 January 2018

1 reference

EASL clinical practice guidelines for HFE hemochromatosis

21 January 2018

1 reference

Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

21 January 2018

1 reference

Defining serum ferritin thresholds to predict clinically relevant liver iron concentrations for guiding deferasirox therapy when MRI is unavailable in patients with non-transfusion-dependent thalassaemia.

21 January 2018

1 reference

Ferritin trends do not predict changes in total body iron in patients with transfusional iron overload.

21 January 2018

1 reference

Management of the thalassemias

21 January 2018

1 reference

Australian guidelines for the assessment of iron overload and iron chelation in transfusion‐dependent thalassaemia major, sickle cell disease and other congenital anaemias

21 January 2018

1 reference

Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort

21 January 2018

1 reference

Cross-talk between available guidelines for the management of patients with beta-thalassemia major

21 January 2018

1 reference

Iron chelation in thalassemia: time to reconsider our comfort zones.

21 January 2018

1 reference

Erythrophagocytosis and recycling of heme iron in normal and pathological conditions; regulation by hepcidin

21 January 2018

1 reference

Physiology and pathophysiology of iron in hemoglobin-associated diseases.

21 January 2018

1 reference

Systemic iron homeostasis

21 January 2018

1 reference

The regulation of iron transport.

21 January 2018

1 reference

Practical management of iron overload.

21 January 2018

1 reference

Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age.

21 January 2018

1 reference

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

21 January 2018

1 reference

Denatured H-ferritin subunit is a major constituent of haemosiderin in the liver of patients with iron overload

21 January 2018

1 reference

Quantitative analysis and modelling of hepatic iron stores using stereology and spatial statistics.

21 January 2018

1 reference

Mechanisms of tissue-iron relaxivity: nuclear magnetic resonance studies of human liver biopsy specimens.

21 January 2018

1 reference

Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron.

21 January 2018

1 reference

Haemosiderin and tissue damage

21 January 2018

1 reference

Labile plasma iron in iron overload: redox activity and susceptibility to chelation

21 January 2018

1 reference

The pathophysiology of transfusional iron overload

21 January 2018

1 reference

A fluorescence-based one-step assay for serum non-transferrin-bound iron

21 January 2018

1 reference

Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders.

21 January 2018

1 reference

Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded beta-thalassemia/HbE patients treated with an oral chelator

21 January 2018

1 reference

Iron toxicity and its possible association with treatment of Cancer: lessons from hemoglobinopathies and rare, transfusion-dependent anemias.

21 January 2018

1 reference

Myelodysplastic syndromes--coping with ineffective hematopoiesis

21 January 2018

1 reference

Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major

21 January 2018

1 reference

Pituitary iron and volume predict hypogonadism in transfusional iron overload

21 January 2018

1 reference

Pancreatic iron and glucose dysregulation in thalassemia major

21 January 2018

1 reference

Iron and cancer: more ore to be mined

21 January 2018

1 reference

Iron and cancer risk--a systematic review and meta-analysis of the epidemiological evidence

21 January 2018

1 reference

Epidemiological and nonclinical studies investigating effects of iron in carcinogenesis--a critical review

21 January 2018

1 reference

Iron and reactive oxygen species: friends or foes of cancer cells?

21 January 2018

1 reference

Utility of labile plasma iron and transferrin saturation in addition to serum ferritin as iron overload markers in different underlying anemias before and after deferasirox treatment.

21 January 2018

1 reference

Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance

21 January 2018

1 reference

Elevated transferrin saturation, health-related quality of life and telomere length

21 January 2018

1 reference

Total mortality by elevated transferrin saturation in patients with diabetes

21 January 2018

1 reference

Associations of Serum Ferritin and Transferrin % Saturation With All-cause, Cancer, and Cardiovascular Disease Mortality: Third National Health and Nutrition Examination Survey Follow-up Study

21 January 2018

1 reference

Transferrin saturation and hospital length of stay and mortality in Medicare beneficiaries

21 January 2018

1 reference

Iron, hemochromatosis, and hepatocellular carcinoma

21 January 2018

1 reference

Elevated serum transferrin saturation and mortality

21 January 2018

1 reference

Iron, lipids, and risk of cancer in the Framingham Offspring cohort

21 January 2018

1 reference

Total and cause-specific mortality by elevated transferrin saturation and hemochromatosis genotype in individuals with diabetes: two general population studies

21 January 2018

1 reference

Free radicals and diabetes

21 January 2018

1 reference

Elevated transferrin saturation and risk of diabetes: three population-based studies

21 January 2018

1 reference

Efficacy and safety of IV ferumoxytol for adults with iron deficiency anemia previously unresponsive to or unable to tolerate oral iron

21 January 2018

1 reference

Association of iron indices and type 2 diabetes: a meta-analysis of observational studies

21 January 2018

1 reference

Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis

21 January 2018

1 reference

21 January 2018

1 reference

Complications of thalassemia major and their treatment

21 January 2018

1 reference

The association of biomarkers of iron status with peripheral arterial disease in US adults

21 January 2018

1 reference

Thalassaemia and risk of cancer: a population-based cohort study

21 January 2018

1 reference

Malignancies in patients with beta-thalassemia major and beta-thalassemia intermedia: a multicenter study in Iran.

21 January 2018

1 reference

Iron overload in patients with myelodysplastic syndromes

21 January 2018

1 reference

Positive effects on hematopoiesis in patients with myelodysplastic syndrome receiving deferasirox as oral iron chelation therapy: a brief review

21 January 2018

1 reference

Increased serum hepcidin levels during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndrome

21 January 2018

1 reference

Iron chelation therapy associated with improvement of hematopoiesis in transfusion-dependent patients

21 January 2018

1 reference

Red blood cell transfusion independence following the initiation of iron chelation therapy in myelodysplastic syndrome

21 January 2018

1 reference

Deferasirox treatment improved the hemoglobin level and decreased transfusion requirements in four patients with the myelodysplastic syndrome and primary myelofibrosis.

21 January 2018

1 reference

Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes

21 January 2018

1 reference

Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial).

21 January 2018

1 reference

The impact of chelation therapy on survival in transfusional iron overload: a meta-analysis of myelodysplastic syndrome.

21 January 2018

1 reference

Restoration of Hematopoiesis After Iron Chelation Therapy With Deferasirox in 2 Children With Severe Aplastic Anemia

21 January 2018

1 reference

Remission from transfusion-dependence in a patient with congenital dyserythropoietic anemia (CDA) and increased intensity of iron chelation.

21 January 2018

1 reference

Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cells in vitro and suppresses hematopoiesis in iron overload patients

21 January 2018

1 reference

Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox.

21 January 2018

1 reference

Exogenous iron increases hemoglobin in beta-thalassemic mice

21 January 2018

1 reference

Ineffective erythropoiesis and thalassemias

21 January 2018

1 reference

Iron overload impairs proliferation of erythroid progenitors cells (BFU-E) from patients with myelodysplastic syndromes

21 January 2018

1 reference

The role of ineffective erythropoiesis in non-transfusion-dependent thalassemia

21 January 2018

1 reference

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

21 January 2018

1 reference

Glucose metabolism after normalization of markers of iron overload by venesection in subjects with hereditary hemochromatosis.

21 January 2018

1 reference

No effect of deferoxamine therapy on glucose homeostasis and insulin secretion in individuals with NIDDM and elevated serum ferritin.

21 January 2018

1 reference

Blood letting in high-ferritin type 2 diabetes: effects on insulin sensitivity and beta-cell function

21 January 2018

1 reference

Hepatic iron concentration and total body iron stores in thalassemia major

21 January 2018

1 reference

Estimating tissue iron burden: current status and future prospects

21 January 2018

1 reference

Iron Chelation in Thalassemia Major

21 January 2018

1 reference

Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias.

21 January 2018

1 reference

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/NYAS.13060

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27186942 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 reference