Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy (Q38829673)

10 July 2018

title

Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy (English)

1 reference

10 July 2018

22

David M Holtzman

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10 July 2018

7

Bruce L Miller

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10 July 2018

6

Adam L Boxer

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10 July 2018

Nigel J Cairns

12

object named as

Nigel J Cairns

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10 July 2018

author name string

Kiran Yanamandra

1

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10 July 2018

Tirth K Patel

2

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10 July 2018

Hong Jiang

3

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10 July 2018

Suzanne Schindler

4

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10 July 2018

Jason D Ulrich

5

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10 July 2018

Diana R Kerwin

8

1 reference

10 July 2018

Gilbert Gallardo

9

1 reference

10 July 2018

Floy Stewart

10

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10 July 2018

Mary Beth Finn

11

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10 July 2018

Philip B Verghese

13

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10 July 2018

Ilana Fogelman

14

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10 July 2018

Tim West

15

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10 July 2018

Joel Braunstein

16

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Grace Robinson

17

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10 July 2018

Jennifer Keyser

18

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10 July 2018

Joseph Roh

19

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10 July 2018

Stephanie S Knapik

20

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10 July 2018

Yan Hu

21

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10 July 2018

language of work or name

English

0 references

publication date

1 April 2017

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10 July 2018

Science Translational Medicine

published in

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10 July 2018

volume

9

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10 July 2018

issue

386

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10 July 2018

Nmnat1 protects neuronal function without altering phospho-tau pathology in a mouse model of tauopathy

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15 July 2018

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Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders

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Anti-tau antibody reduces insoluble tau and decreases brain atrophy

15 July 2018

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Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

15 July 2018

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Neuronal activity regulates extracellular tau in vivo

15 July 2018

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Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers

15 July 2018

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Plasma tau levels in Alzheimer's disease

15 July 2018

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Physiological release of endogenous tau is stimulated by neuronal activity.

15 July 2018

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Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathology

15 July 2018

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Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.

15 July 2018

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Biochemistry and cell biology of tau protein in neurofibrillary degeneration

15 July 2018

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Propagation of tau pathology in a model of early Alzheimer's disease

15 July 2018

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Trans-synaptic spread of tau pathology in vivo

15 July 2018

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Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

15 July 2018

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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

15 July 2018

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Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.

15 July 2018

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

15 July 2018

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Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

15 July 2018

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Alzheimer's disease: the challenge of the second century

15 July 2018

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Simultaneous Detection of Single Molecules and Singulated Ensembles of Molecules Enables Immunoassays with Broad Dynamic Range

15 July 2018

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Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

15 July 2018

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Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

15 July 2018

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Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

15 July 2018

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Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

15 July 2018

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

15 July 2018

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

15 July 2018

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Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment

15 July 2018

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Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules

15 July 2018

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Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

15 July 2018

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Analysis of in vivo turnover of tau in a mouse model of tauopathy

15 July 2018

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Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

22 August 2018

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Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

22 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727571

Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein

22 August 2018

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Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.

22 August 2018

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Rapid cerebral amyloid binding by Aβ antibodies infused into β-amyloid precursor protein transgenic mice

22 August 2018

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Passive immunization of the Abeta42(43) C-terminal-specific antibody BC05 in a mouse model of Alzheimer's disease

22 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727571

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

22 August 2018

1 reference

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In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727571

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727571

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727571

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease

22 August 2018

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Progressive supranuclear palsy: extensive neuropil threads in addition to neurofibrillary tangles. Very similar antigenicity of subcortical neuronal pathology in progressive supranuclear palsy and Alzheimer's disease

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28424326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Staging of argyrophilic grains: an age-associated tauopathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28424326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cerebrospinal Fluid Tau Levels in Neurodegenerative Diseases with Distinct Tau-Related Pathology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28424326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.AAL2029

1 reference

10 July 2018

PMC publication ID

5727571

1 reference

10 July 2018

PubMed publication ID

28424326

1 reference

10 July 2018