Impact of Glycosylation on Effector Functions of Therapeutic IgG (Q38818688)

6 September 2017

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title

Impact of Glycosylation on Effector Functions of Therapeutic IgG (English)

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6 September 2017

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Riad Abès

1

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PMC publication ID

3991024

6 September 2017

Jean-Luc Teillaud

series ordinal

2

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6 September 2017

12 January 2010

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6 September 2017

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6 September 2017

3

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6 September 2017

1

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6 September 2017

146-157

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Creative Commons Attribution 4.0 International

6 September 2017

start time

12 January 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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1 reference

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Glycosylation as a strategy to improve antibody-based therapeutics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

IgG glycosylation analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Identification of a receptor required for the anti-inflammatory activity of IVIG.

9 September 2017

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Fcgamma receptors as regulators of immune responses

9 September 2017

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FcgammaR: The key to optimize therapeutic antibodies?

9 September 2017

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FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin

9 September 2017

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The antiinflammatory activity of IgG: the intravenous IgG paradox

9 September 2017

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The impact of glycosylation on the biological function and structure of human immunoglobulins.

9 September 2017

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Intravenous immunoglobulin ameliorates ITP via activating Fc gamma receptors on dendritic cells

9 September 2017

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Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.

9 September 2017

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Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

9 September 2017

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Inhibition of immune responses by ITAM-bearing receptors

9 September 2017

1 reference

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Enhanced natural killer cell binding and activation by low-fucose IgG1 antibody results in potent antibody-dependent cellular cytotoxicity induction at lower antigen density

9 September 2017

1 reference

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Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity

9 September 2017

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The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease

9 September 2017

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Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease

9 September 2017

1 reference

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Immunomodulation of autoimmune and inflammatory diseases with intravenous immune globulin

9 September 2017

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Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Fc receptors are required in passive and active immunity to melanoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Agalactosyl glycoforms of IgG autoantibodies are pathogenic

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Galactosylation of human IgG monoclonal anti-D produced by EBV-transformed B-lymphoblastoid cell lines is dependent on culture method and affects Fc receptor-mediated functional activity.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Biological significance of carbohydrate chains on monoclonal antibodies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Glycosylation of a VH residue of a monoclonal antibody against alpha (1----6) dextran increases its affinity for antigen

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Antibody variable region glycosylation: position effects on antigen binding and carbohydrate structure

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

A Waldenström macroglobulin that is both a cold agglutinin and a cryoglobulin because it binds N -acetylneuraminosyl residues

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Selection of a human anti-RhD monoclonal antibody for therapeutic use: impact of IgG glycosylation on activating and inhibitory Fc gamma R functions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Significance and molecular basis for IgG glycosylation changes in rheumatoid arthritis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Atypical glycosylation of an IgG monoclonal cryoimmunoglobulin

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991024

Control of IgG/Fc glycosylation: a comparison of oligosaccharides from chimeric human/mouse and mouse subclass immunoglobulin Gs.

17 June 2018

1 reference

Chronic lymphocytic leukaemia cells are efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of FcgammaRIIIA/CD16.

21 January 2018

1 reference

DC-SIGN and alpha2,6-sialylated IgG Fc interaction is dispensable for the anti-inflammatory activity of IVIg on human dendritic cells

21 January 2018

1 reference

Prognostic relevance of 6q deletion in Waldenström's macroglobulinemia: a multicenter study

21 January 2018

1 reference

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

21 January 2018

1 reference

Activating and inhibitory Fcγ receptors in immunotherapy: being the actor or being the target

21 January 2018

1 reference

Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy

21 January 2018

1 reference

Immunoglobulines intraveineuses dans les maladies auto-immunes et inflammatoires : au-delà d’une simple substitution

21 January 2018

1 reference

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

21 January 2018

1 reference

12 December 2020

Structure of asymmetric non-precipitating antibody: presence of a carbohydrate residue in only one Fab region of the molecule

1 reference

12 December 2020

The three-dimensional structure of the carbohydrate within the Fc fragment of immunoglobulin G

1 reference

12 December 2020

Agalactosyl IgG: an aid to differential diagnosis in early synovitis

1 reference

12 December 2020

Identifiers

DOI

10.3390/PH3010146

1 reference

6 September 2017

1 reference

PMC publication ID

3991024

6 September 2017

PubMed publication ID

27713246

1 reference

PMC publication ID

3991024