Equilibrium Ensembles for Insulin Folding from Bias-Exchange Metadynamics (Q38818418)

http://europepmc.org/abstract/PMC/5406382

20 May 2018

title

Equilibrium Ensembles for Insulin Folding from Bias-Exchange Metadynamics (English)

1 reference

http://europepmc.org/abstract/PMC/5406382

20 May 2018

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Richa Singh

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

Anurag Singh Rathore

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

Gaurav Goel

series ordinal

4

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7 June 2020

language of work or name

English

0 references

publication date

1 April 2017

1 reference

http://europepmc.org/abstract/PMC/5406382

20 May 2018

published in

Biophysical Journal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

volume

112

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

issue

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

1571-1585

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

Molecular Dynamics Simulations of Insulin: Elucidating the Conformational Changes that Enable Its Binding

7 June 2020

cites work

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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Solvation-assisted pressure tuning of insulin fibrillation: from novel aggregation pathways to biotechnological applications

31 August 2018

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31 August 2018

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Solvational tuning of the unfolding, aggregation and amyloidogenesis of insulin

31 August 2018

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31 August 2018

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Ethanol-perturbed amyloidogenic self-assembly of insulin: looking for origins of amyloid strains

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

In vitro refolding of human proinsulin. Kinetic intermediates, putative disulfide-forming pathway folding initiation site, and potential role of C-peptide in folding process

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Convergence of sampling in protein simulations.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Crystallization and preliminary crystallographic investigation of a low-pH native insulin monomer with flexible behaviour.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Essential dynamics of reversible peptide folding: memory-free conformational dynamics governed by internal hydrogen bonds.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Probing the mechanism of insulin fibril formation with insulin mutants

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

On the convergence of the conformational coordinates basis set obtained by the essential dynamics analysis of proteins' molecular dynamics simulations.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Effect of solvent on collective motions in globular protein.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

Local cooperativity in the unfolding of an amyloidogenic variant of human lysozyme

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5406382

A comparison of the dynamic behavior of monomeric and dimeric insulin shows structural rearrangements in the active monomer

3 December 2018

1 reference

12 December 2020

Assessing the Accuracy of Metadynamics†

1 reference

12 December 2020

Insulin Wakayama: familial mutant insulin syndrome in Japan

1 reference

12 December 2020

Protein flexibility: Multiple molecular dynamics simulations of insulin chain B

1 reference

12 December 2020

Molecular dynamics simulation of β2-microglobulin in denaturing and stabilizing conditions

1 reference

12 December 2020

Dynamics of a monomeric insulin analogue: testing the molten-globule hypothesis

1 reference

12 December 2020

Detection of an equilibrium intermediate in the folding of a monomeric insulin analog

1 reference

12 December 2020

Statistical mechanics of the denatured state of a protein using replica-averaged metadynamics

1 reference

12 December 2020

Comparative 2D NMR studies of human insulin and des-pentapeptide insulin: sequential resonance assignment and implications for protein dynamics and receptor recognition

1 reference

12 December 2020

Dissecting the hydrogen exchange properties of insulin under amyloid fibril forming conditions: a site-specific investigation by mass spectrometry

1 reference

12 December 2020

Implications of invariant residue LeuB6 in insulin-receptor interactions

1 reference

12 December 2020

Thermal dissociation and unfolding of insulin

1 reference

12 December 2020

Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics

1 reference

12 December 2020

Small proteins fold through transition states with native-like topologies

1 reference

12 December 2020

Acid stabilization of insulin

1 reference

12 December 2020

Equilibrium intermediates in the denaturation of human insulin and two monomeric insulin analogs

1 reference

12 December 2020

Langevin model of the temperature and hydration dependence of protein vibrational dynamics

1 reference

12 December 2020

Transmission of conformational change in insulin

1 reference

12 December 2020

Conformational dynamics of insulin in solution. Circular dichroic studies

1 reference

12 December 2020

Importance of individual side chains for the stability of a protein fold: computational alanine scanning of the insulin monomer

1 reference

12 December 2020

Aggregation of bovine insulin probed by DSC/PPC calorimetry and FTIR spectroscopy

1 reference

12 December 2020

Denaturation versus unfolding: energetic aspects of residual structure in denatured alpha-lactalbumin

1 reference

12 December 2020

Convergence of molecular dynamics simulations of membrane proteins

1 reference

12 December 2020

Alanine scanning mutagenesis of insulin

1 reference

12 December 2020

Primary steps of pH-dependent insulin aggregation kinetics are governed by conformational flexibility

1 reference

12 December 2020

10.1016/J.BPJ.2017.03.015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28445749 AND SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

28445749

1 reference