Cell interactions and genetic regulation that contribute to testicular Leydig cell development and differentiation. (Q38808601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

title

Cell interactions and genetic regulation that contribute to testicular Leydig cell development and differentiation (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Luc J Martin

series ordinal

1

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6 September 2017

publication date

26 April 2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

Molecular Reproduction and Development

1 April 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

volume

83

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

470-487

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

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SF-1: a critical mediator of steroidogenesis

21 January 2018

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Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells

21 January 2018

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Human testicular insulin-like factor 3: in relation to development, reproductive hormones and andrological disorders

21 January 2018

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Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone axis

21 January 2018

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The effects of gonadotropin suppression and selective replacement on insulin-like factor 3 secretion in normal adult men.

21 January 2018

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Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism

21 January 2018

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Differentiation of adult Leydig cells.

21 January 2018

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Transcription of platelet-derived growth factor receptor in Leydig cells involves specificity protein 1 and 3

21 January 2018

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Liposome-mediated macrophage depletion: an experimental approach to study the role of testicular macrophages in the rat.

21 January 2018

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GATA-4 is required for sex steroidogenic cell development in the fetal mouse

21 January 2018

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The LIM homeobox gene Lhx9 is essential for mouse gonad formation

21 January 2018

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Sertoli cell signaling by Desert hedgehog regulates the male germline

21 January 2018

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The Notch signaling pathway: transcriptional regulation at Notch target genes

21 January 2018

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Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad

21 January 2018

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Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis

21 January 2018

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Cadherins and cadherin-associated molecules in the developing and maturing rat testis

21 January 2018

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Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells

21 January 2018

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Interleukin-1 inhibits Leydig cell steroidogenesis in primary culture

21 January 2018

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Mutations in the desert hedgehog (DHH) gene in patients with 46,XY complete pure gonadal dysgenesis

21 January 2018

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Characterization of two patched receptors for the vertebrate hedgehog protein family

21 January 2018

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Oestrogens and spermatogenesis

21 January 2018

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Response to acute hCG stimulation and steroidogenic potential of Leydig cell fibroblastic precursors in humans

21 January 2018

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Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development

21 January 2018

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The blood-testis barrier and its implications for male contraception

21 January 2018

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Leydig cells: From stem cells to aging

21 January 2018

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Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions

21 January 2018

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Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules

21 January 2018

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Absence of colony-stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects.

21 January 2018

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Endothelin stimulates testosterone secretion by rat Leydig cells

21 January 2018

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Two distinct origins for Leydig cell progenitors in the fetal testis.

21 January 2018

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Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor.

21 January 2018

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Steroidogenic factor-1 contributes to the cyclic-adenosine monophosphate down-regulation of human SRY gene expression

21 January 2018

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Follicle-stimulating hormone stimulates estradiol-17beta synthesis in cultured Sertoli cells

21 January 2018

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Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia

21 January 2018

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Number, distribution pattern, and identification of macrophages in the testes of infertile men.

21 January 2018

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In vivo manipulation (depletion versus activation) of testicular macrophages: central and local effects

21 January 2018

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Sertoli cells are the site of interleukin-1α synthesis in rat testis

21 January 2018

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Gene expression in rat leydig cells during development from the progenitor to adult stage: a cluster analysis

21 January 2018

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In search of rat stem Leydig cells: identification, isolation, and lineage-specific development.

21 January 2018

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Leydig cell loss and spermatogenic arrest in platelet-derived growth factor (PDGF)-A-deficient mice

21 January 2018

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Origin, differentiation and regulation of fetal and adult Leydig cells

21 January 2018

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Cell biology of Leydig cells in the testis

21 January 2018

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Testicular macrophage modulation of Leydig cell steroidogenesis

21 January 2018

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Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis

21 January 2018

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Direct Inhibitory Effect of Estrogen on Leydig Cell Function of Hypophysectomized Rats

21 January 2018

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Fetal testis--a very special endocrine organ

21 January 2018

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Fetal Leydig cells: cellular origin, morphology, life span, and special functional features

21 January 2018

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Gata4 is required for formation of the genital ridge in mice

21 January 2018

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Relaxin-like factor: a highly specific and constitutive new marker for Leydig cells in the human testis

21 January 2018

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The androgen microenvironment of the human testis and hormonal control of spermatogenesis

21 January 2018

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The Sertoli cell in vivo and in vitro

21 January 2018

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Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function

21 January 2018

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Constitutive expression of interleukin-1alpha messenger ribonucleic acid in rat Sertoli cells is dependent upon interaction with germ cells

21 January 2018

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Sex hormones and sexual function in obese men losing weight

21 January 2018

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Paracrine regulation of mammalian oocyte maturation and male germ cell survival

21 January 2018

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Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

21 January 2018

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Gonadal transactivation of STARD1, CYP11A1 and HSD3B.

21 January 2018

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Oxysterols regulate expression of the steroidogenic acute regulatory protein

21 January 2018

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Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

21 January 2018

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Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

21 January 2018

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Gata4 regulates testis expression of Dmrt1.

21 January 2018

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Transforming growth factor-beta inhibits Leydig cell steroidogenesis in primary culture

21 January 2018

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Regulation of Leydig cell function in primary culture by inhibin and activin

21 January 2018

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Stem cell factor and c-kit in the mammalian testis: lessons originating from Mother Nature's gene knockouts

21 January 2018

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Regulation of Leydig cells through a steroidogenic acute regulatory protein-independent pathway by a lipophilic factor from macrophages

21 January 2018

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Production of 25-hydroxycholesterol by testicular macrophages and its effects on Leydig cells

21 January 2018

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cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism

21 January 2018

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

21 January 2018

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Rhox: a new homeobox gene cluster

21 January 2018

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cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation.

21 January 2018

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Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family

21 January 2018

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The regulation of Sox9 gene expression by the GATA4/FOG2 transcriptional complex in dominant XX sex reversal mouse models

21 January 2018

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21 January 2018

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Functional Cooperation Between GATA Factors and cJUN on the Star Promoter in MA‐10 Leydig Cells

21 January 2018

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The orphan nuclear receptor NUR77 regulates hormone-induced StAR transcription in Leydig cells through cooperation with Ca2 /calmodulin-dependent protein kinase I.

21 January 2018

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The human 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase type 2 promoter is a novel target for the immediate early orphan nuclear receptor Nur77 in steroidogenic cells.

21 January 2018

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Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility

21 January 2018

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Lhx9 expression during gonadal morphogenesis as related to the state of cell differentiation

21 January 2018

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Leydig cell-specific expression of DAX1 improves fertility of the Dax1-deficient mouse.

21 January 2018

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Differentiation of the adult Leydig cell population in the postnatal testis

21 January 2018

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The INSL3 gene is a direct target for the orphan nuclear receptor, COUP-TFII, in Leydig cells

21 January 2018

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The nuclear receptor NR2F2 activates star expression and steroidogenesis in mouse MA-10 and MLTC-1 Leydig cells

21 January 2018

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Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha

21 January 2018

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Structure, cytochemistry, endocytic activity, and immunoglobulin (Fc) receptors of rat testicular interstitial-tissue macrophages

21 January 2018

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21 January 2018

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Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle

21 January 2018

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Regulation of the proliferation and differentiation of Leydig stem cells in the adult testis

21 January 2018

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Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men.

21 January 2018

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Androgen receptor roles in spermatogenesis and infertility

21 January 2018

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The foetal Leydig cell-- differentiation, function and regulation

21 January 2018

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Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester

21 January 2018

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Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells

21 January 2018

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Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes

21 January 2018

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Development and cytodifferentiation of peritubular myoid cells in the rat testis

21 January 2018

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The roles of steroidogenic factor-1 in reproductive function

21 January 2018

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Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.

21 January 2018

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A developmental study of the Desert hedgehog-null mouse testis

21 January 2018

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Porcine SRY promoter is a target for steroidogenic factor 1.

21 January 2018

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Ultrastructural evidence of mature Leydig cells and Leydig cell regression in the neonatal human testis

21 January 2018

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The triphasic nature of Leydig cell development in humans, and comments on nomenclature

21 January 2018

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Essential roles of COUP-TFII in Leydig cell differentiation and male fertility

21 January 2018

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Development and regulation of growth and differentiated function in human and subhuman primate fetal gonads

21 January 2018

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Human chorionic gonadotropin increases the concentration of macrophages in neonatal rat testis

21 January 2018

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Regulation of the macrophage population in postnatal rat testis

21 January 2018

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Sertoli cells maintain Leydig cell number and peritubular myoid cell activity in the adult mouse testis

21 January 2018

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Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

21 January 2018

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Sertoli-Leydig cell communications.

21 January 2018

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The PDGF signaling pathway controls multiple steroid-producing lineages

21 January 2018

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Expression of Pbx1b during mammalian organogenesis

21 January 2018

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GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.

21 January 2018

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Evidence for the presence of nerve growth factor (NGF) and NGF receptors in human testis

21 January 2018

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Immunohistochemical analysis of androgen effects on androgen receptor expression in developing Leydig and Sertoli cells

21 January 2018

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Developmental changes in levels of luteinizing hormone receptor and androgen receptor in rat Leydig cells

21 January 2018

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Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis

21 January 2018

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Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes.

21 January 2018

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Regulation of P450c17 expression in the early embryo depends on GATA factors

21 January 2018

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Localization and regulation of aromatase liver receptor homologue-1 in the developing rat testis

21 January 2018

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Cell-cell interactions in the testis

21 January 2018

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Transforming growth factor-alpha gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions

21 January 2018

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Identification, proliferation, and differentiation of adult Leydig stem cells

21 January 2018

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Stem Leydig cell differentiation: gene expression during development of the adult rat population of Leydig cells

21 January 2018

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Presence of Identical Mitochondrial Proteins in Unstimulated Constitutive Steroid-Producing R2C Rat Leydig Tumor and Stimulated Nonconstitutive Steroid-Producing MA-10 Mouse Leydig Tumor Cells*

21 January 2018

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Notch signaling maintains Leydig progenitor cells in the mouse testis

21 January 2018

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Morphological and functional maturation of Leydig cells: from rodent models to primates

21 January 2018

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Novel roles for GATA transcription factors in the regulation of steroidogenesis

21 January 2018

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Induction of Testicular Aromatization by Luteinizing Hormone in Mature Rats*

21 January 2018

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Identification of the link between the hypothalamo-pituitary axis and the testicular orphan nuclear receptor NR0B2 in adult male mice

21 January 2018

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Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility

21 January 2018

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Differentiation of the fetal gonad.

21 January 2018

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Molecular mechanisms of testosterone action in spermatogenesis

21 January 2018

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Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis

21 January 2018

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Morphometric studies on rat seminiferous tubules

21 January 2018

1 reference

Pituitary-Gonadal Relations in Infancy. I. Patterns of Serum Gonadotropin Concentrations from Birth to Four Years of Age in Man and Chimpanzee

21 January 2018

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Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

21 January 2018

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Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice

21 January 2018

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Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

21 January 2018

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NGF induces adult stem Leydig cells to proliferate and differentiate during Leydig cell regeneration

21 January 2018

1 reference

Tissue-specific knockouts of steroidogenic factor 1.

21 January 2018

1 reference

Targeted disruption of the Insl3 gene causes bilateral cryptorchidism

21 January 2018

1 reference

Insulin-Like Factor 3: A Novel Circulating Hormone of Testicular Origin in Humans

21 January 2018

1 reference

Sertoli–Leydig cell communication via an LHRH-like factor

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MRD.22648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27079813 AND SRC:MED&resulttype=core&format=json

1 April 2020

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