Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics. (Q38803170)

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26 March 2020

title

Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics (English)

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26 March 2020

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5

Howard A Stone

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26 March 2020

author name string

Nicole Taylor

1

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26 March 2020

Shana Elbaum-Garfinkle

2

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26 March 2020

Nilesh Vaidya

3

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26 March 2020

Huaiying Zhang

4

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26 March 2020

Clifford P Brangwynne

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26 March 2020

publication date

1 November 2016

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26 March 2020

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26 March 2020

volume

12

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issue

45

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26 March 2020

page(s)

9142-9150

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describes a project that uses

26 March 2020

1 reference

Polymer physics of intracellular phase transitions

1 reference

Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

21 January 2018

1 reference

Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs

21 January 2018

1 reference

Stress granules as crucibles of ALS pathogenesis.

21 January 2018

1 reference

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

21 January 2018

1 reference

Inverse size scaling of the nucleolus by a concentration-dependent phase transition

21 January 2018

1 reference

PolyQ-dependent RNA-protein assemblies control symmetry breaking

21 January 2018

1 reference

Germline P granules are liquid droplets that localize by controlled dissolution/condensation

21 January 2018

1 reference

Direct visual observation of thermal capillary waves

21 January 2018

1 reference

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

21 January 2018

1 reference

RNA transcription modulates phase transition-driven nuclear body assembly

21 January 2018

1 reference

Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles

21 January 2018

1 reference

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling

21 January 2018

1 reference

Phase transitions in the assembly of multivalent signalling proteins

21 January 2018

1 reference

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

21 January 2018

1 reference

Intrinsically disordered proteins and intrinsically disordered protein regions

21 January 2018

1 reference

Classification of intrinsically disordered regions and proteins

21 January 2018

1 reference

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

21 January 2018

1 reference

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

21 January 2018

1 reference

Altered ribostasis: RNA-protein granules in degenerative disorders

21 January 2018

1 reference

RNA-binding proteins with prion-like domains in ALS and FTLD-U

21 January 2018

1 reference

A systematic survey identifies prions and illuminates sequence features of prionogenic proteins

21 January 2018

1 reference

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

21 January 2018

1 reference

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

21 January 2018

1 reference

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

21 January 2018

1 reference

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

21 January 2018

1 reference

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization

21 January 2018

1 reference

RNA Controls PolyQ Protein Phase Transitions.

21 January 2018

1 reference

Getting RNA and protein in phase

21 January 2018

1 reference

It's Raining Liquids: RNA Tunes Viscoelasticity and Dynamics of Membraneless Organelles

21 January 2018

1 reference

Translation repressors, an RNA helicase, and developmental cues control RNP phase transitions during early development.

21 January 2018

1 reference

A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells

21 January 2018

1 reference

Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins

21 January 2018

1 reference

Surface-induced droplet fusion in microfluidic devices

21 January 2018

1 reference

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

21 January 2018

1 reference

A microfluidic rectifier: anisotropic flow resistance at low Reynolds numbers.

21 January 2018

1 reference

Microfluidic Memory and Control Devices

21 January 2018

1 reference

Viscosimeter on a microfluidic chip

21 January 2018

1 reference

Liquid-liquid phase separation in biology

21 January 2018

1 reference

Protein aggregation: folding aggregates, inclusion bodies and amyloid

21 January 2018

1 reference

Particle tracking using confocal microscopy to probe the microrheology in a phase-separating emulsion containing nonadsorbing polysaccharide

21 January 2018

1 reference

A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin

21 January 2018

1 reference

The long unwinding road of RNA helicases

21 January 2018

1 reference

Nucleolar proteome dynamics

21 January 2018

1 reference

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

21 January 2018

1 reference

Nonequilibrium mechanics of active cytoskeletal networks

21 January 2018

1 reference

Active, motor-driven mechanics in a DNA gel

21 January 2018

1 reference

Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events

21 January 2018

1 reference

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

21 January 2018

1 reference

The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation

21 January 2018

1 reference

Spatial Organization of the Cell Cytoplasm by Position-Dependent Phase Separation

21 January 2018

1 reference

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

21 January 2018

1 reference

12 December 2020

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles.

1 reference

12 December 2020

Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities

1 reference

12 December 2020

Nucleolar localization of nucleophosmin/B23 requires GTP.

1 reference

12 December 2020

Identifiers

DOI

10.1039/C6SM01087C

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791212 AND SRC:MED&resulttype=core&format=json

26 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791212 AND SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

27791212

1 reference