PIKfyve inhibition increases exosome release and induces secretory autophagy (Q38756823)

6 September 2017

title

PIKfyve inhibition increases exosome release and induces secretory autophagy (English)

1 reference

6 September 2017

0 references

Maria Lyngaas Torgersen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

11 June 2020

Alicia Llorente

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

11 June 2020

2

Anders Øverbye

1 reference

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11 June 2020

6

Kirsten Sandvig

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

11 June 2020

Nina Pettersen Hessvik

1

object named as

Nina Pettersen Hessvik

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

Andreas Brech

3

object named as

Andreas Brech

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

author name string

Ida Seim Jakobsen

5

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11 June 2020

publication date

20 July 2016

1 reference

Cellular and Molecular Life Sciences

6 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

11 June 2020

volume

73

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11 June 2020

issue

24

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11 June 2020

page(s)

4717-4737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes

11 June 2020

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Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling

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Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation

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Ceramide triggers budding of exosome vesicles into multivesicular endosomes

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Regulation of exosome release by glycosphingolipids and flotillins

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Rab27a and Rab27b control different steps of the exosome secretion pathway

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Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner

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Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion

21 January 2018

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Aβ secretion and plaque formation depend on autophagy

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Phosphoinositides in cell regulation and membrane dynamics

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Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).

21 January 2018

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21 January 2018

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Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

21 January 2018

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The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.

21 January 2018

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A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding

21 January 2018

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PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling

21 January 2018

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Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

21 January 2018

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WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.

21 January 2018

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21 January 2018

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Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel

21 January 2018

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Proteomics analysis of bladder cancer exosomes.

21 January 2018

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Lithium: a key to the genetics of bipolar disorder

21 January 2018

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A computational screen for mouse signaling pathways targeted by microRNA clusters.

21 January 2018

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Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

21 January 2018

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Unconventional secretion of Acb1 is mediated by autophagosomes.

21 January 2018

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The autophagic machinery ensures nonlytic transmission of mycobacteria

21 January 2018

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Exosomes contain ubiquitinated proteins.

21 January 2018

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Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion

21 January 2018

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Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells

21 January 2018

1 reference

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Microautophagy of cytosolic proteins by late endosomes

21 January 2018

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Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27438886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Exosomes: composition, biogenesis and function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27438886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00018-016-2309-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27438886 AND SRC:MED&resulttype=core&format=json

11 June 2020

1 reference