Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint (Q38748101)

19 May 2018

title

Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint (English)

1 reference

19 May 2018

author

José Rueff

1

1 reference

12 May 2018

António Sebastião Rodrigues

2

1 reference

12 May 2018

author name string

José Rueff

1

1 reference

27340700

11 May 2018

http://europepmc.org/abstract/MED/27340700

António Sebastião Rodrigues

2

1 reference

27340700

11 May 2018

http://europepmc.org/abstract/MED/27340700

language of work or name

English

0 references

publication date

1 January 2016

1 reference

19 May 2018

Methods in Molecular Biology

number of pages

18

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based on heuristic

inferred from page(s)

published in

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19 May 2018

volume

1395

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19 May 2018

page(s)

1-18

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19 May 2018

Mechanisms of cancer drug resistance

cites work

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Genomics and cancer drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Cancer drug resistance: an evolving paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Cancer immunoediting from immune surveillance to immune escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Molecular mechanisms of drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Clinical guidelines, the politics of value, and the practice of medicine: physicians at the crossroads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Cytochrome P450s and other enzymes in drug metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Functional characterization of eight human CYP1A2 variants: the role of cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Pharmacogenetics of tamoxifen: who should undergo CYP2D6 genetic testing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Heterogeneity in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Mutational heterogeneity in human cancers: origin and consequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

The paradox of cancer cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

The causes and consequences of genetic heterogeneity in cancer evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Oncogene addiction: setting the stage for molecularly targeted cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

"Just caring": can we afford the ethical and economic costs of circumventing cancer drug resistance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Cancer. Addiction to oncogenes--the Achilles heal of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Recurrent oral cancer: current and emerging therapeutic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Steroid receptor coactivator-3 as a potential molecular target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Mechanisms of drug resistance in cancer chemotherapy: coordinated role and regulation of efflux transporters and metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

ABCG2: determining its relevance in clinical drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

The c-MET/PI3K signaling is associated with cancer resistance to doxorubicin and photodynamic therapy by elevating BCRP/ABCG2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Contrary to adult patients, expression of the multidrug resistance gene (MDR1) fails to define a poor prognostic group in childhood AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Clonal evolution in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

MicroRNAs and their relevance to ABC transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Molecular pathways: exploiting tumor-specific molecular defects in DNA repair pathways for precision cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Molecular mechanisms of epistasis within and between genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Estrogen receptor mutations and their role in breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Mechanisms of resistance to endocrine therapy in breast cancer: focus on signaling pathways, miRNAs and genetically based resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

SRC-3/AIB1: transcriptional coactivator in oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Tumor and its microenvironment: a synergistic interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Biomarkers and the genetics of early neoplastic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Landscaper seeks remunerative position

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

21 January 2018

Cancer genome landscapes

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Multidrug resistance in cancer: role of ATP-dependent transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Mechanism-based cancer therapy: resistance to therapy, therapy for resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Comparative lesion sequencing provides insights into tumor evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Evolutionary dynamics of cancer in response to targeted combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Combination of two but not three current targeted drugs can improve therapy of chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

Molecular profiling of single circulating tumor cells with diagnostic intention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-3347-1_1

10.1007/978-1-4939-3347-1_1

21 January 2018

Identifiers

DOI

1 reference

19 May 2018

1 reference

19 May 2018