Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma (Q38730889)

5 September 2017

title

Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma (English)

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5 September 2017

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Huixing Zhou

1

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5 September 2017

Yuan Jian

2

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5 September 2017

Yun Leng

3

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5 September 2017

Nian Liu

4

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5 September 2017

Ying Tian

5

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5 September 2017

Guorong Wang

6

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5 September 2017

Wen Gao

7

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5 September 2017

Guangzhong Yang

8

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5 September 2017

Wenming Chen

9

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5 September 2017

publication date

15 November 2016

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International Journal of Hematology

5 September 2017

published in

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5 September 2017

volume

105

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5 September 2017

issue

3

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5 September 2017

page(s)

318-325

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Molecular genetics and structural biology of human MutT homolog, MTH1.

5 September 2017

cites work

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https://api.crossref.org/works/10.1007/S12185-016-2139-3

Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Contribution of hMTH1 to the maintenance of 8-oxoguanine levels in lung DNA of non-small-cell lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

SCH 51344-induced reversal of RAS-transformation is accompanied by the specific inhibition of the RAS and RAC-dependent cell morphology pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Improvement in survival of older adults with multiple myeloma: results of an updated period analysis of SEER data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Clinical and biological significance of RAS mutations in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Molecular basis of resistance to proteasome inhibitors in hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Persistent oxidative stress in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Mitochondrial dysfunction contributes to oncogene-induced senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

New Targets and New Agents in High-Risk Multiple Myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Ras oncogene mutation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Bortezomib (Velcadetrade mark) in the Treatment of Multiple Myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Frail elderly patients with relapsed-refractory multiple myeloma: efficacy and toxicity profile of the combination of bortezomib, high-dose dexamethasone, and low-dose oral cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Manipulation of cellular redox parameters for improving therapeutic responses in B-cell lymphoma and multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Cancer phenotypic lethality, exemplified by the non-essential MTH1 enzyme being required for cancer survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12185-016-2139-3

Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer

21 January 2018

1 reference

12 December 2020

Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasias

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12 December 2020

Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer

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12 December 2020

Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer.

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12 December 2020

Major alterations in the nucleotide structure of DNA in cancer of the female breast

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12 December 2020

Increased formation of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes

1 reference

12 December 2020

Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial

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12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

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12 December 2020

10.1007/S12185-016-2139-3

Identifiers

DOI

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Dimensions Publication ID

5 September 2017

1036770248

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