Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia. (Q38729904)

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27 March 2020

title

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia (English)

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27 March 2020

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5

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27 March 2020

Cleo Kontoravdi

6

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27 March 2020

author name string

Si Nga Sou

1

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27 March 2020

Philip M Jedrzejewski

2

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27 March 2020

Ken Lee

3

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27 March 2020

Christopher Sellick

4

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27 March 2020

publication date

10 March 2017

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Biotechnology and Bioengineering

27 March 2020

published in

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27 March 2020

volume

114

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27 March 2020

issue

7

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27 March 2020

page(s)

1570-1582

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Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation

27 March 2020

cites work

1 reference

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Differential response in downstream processing of CHO cells grown under mild hypothermic conditions

6 September 2017

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Metabolic flux analysis in mammalian cell culture

6 September 2017

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Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines

6 September 2017

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The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells

6 September 2017

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Advancing glycomics: implementation strategies at the consortium for functional glycomics

6 September 2017

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Temperature reduction in cultures of hGM-CSF-expressing CHO cells: effect on productivity and product quality

6 September 2017

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Dynamics of immature mAb glycoform secretion during CHO cell culture: An integrated modelling framework.

6 September 2017

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A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

6 September 2017

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A question of size: the eukaryotic proteome and the problems in defining it.

6 September 2017

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Cell line-specific control of recombinant monoclonal antibody production by CHO cells.

6 September 2017

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Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment

14 September 2017

1 reference

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Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells

14 September 2017

1 reference

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Metabolic rates, growth phase, and mRNA levels influence cell-specific antibody production levels from in vitro-cultured mammalian cells at sub-physiological temperatures.

14 September 2017

1 reference

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Maximizing interferon-gamma production by Chinese hamster ovary cells through temperature shift optimization: experimental and modeling

14 September 2017

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How does mild hypothermia affect monoclonal antibody glycosylation?

14 September 2017

1 reference

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A structured model for monoclonal antibody synthesis in exponentially growing and stationary phase hybridoma cells

23 June 2018

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The effect of increasing nucleotide-sugar concentrations on the incorporation of sugars into glycoconjugates in rat hepatocytes.

23 June 2018

1 reference

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Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5485029

Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5485029

Effect of low culture temperature on specific productivity, transcription level, and heterogeneity of erythropoietin in Chinese hamster ovary cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5485029

The effects of temperature on the kinetics and stability of mesophilic and thermophilic 3-phosphoglycerate kinases

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5485029

Advances in the assessment and control of the effector functions of therapeutic antibodies

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869292

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/BIT.26225

1 reference

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27 March 2020

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27 March 2020

PubMed publication ID

27869292

1 reference