Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade (Q38727885)

http://europepmc.org/abstract/PMC/5385895

22 June 2018

title

Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade (English)

1 reference

http://europepmc.org/abstract/PMC/5385895

22 June 2018

author

Joseph L Benci

1

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6 June 2020

Tony J Wu

4

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Christina Twyman-Saint Victor

6 June 2020

6

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6 June 2020

David S M Lee

8

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6 June 2020

11

Tara C Gangadhar

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6 June 2020

18

E John Wherry

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6 June 2020

author name string

Bihui Xu

2

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6 June 2020

Yu Qiu

3

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6 June 2020

Hannah Dada

5

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6 June 2020

Lisa Cucolo

7

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6 June 2020

Kristen E Pauken

9

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6 June 2020

Alexander C Huang

10

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6 June 2020

Ravi K Amaravadi

12

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Lynn M Schuchter

13

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Michael D Feldman

14

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6 June 2020

Robert H Vonderheide

16

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6 June 2020

Amit Maity

17

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6 June 2020

Andy J Minn

19

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6 June 2020

Hemant Ishwaran

15

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6 June 2020

language of work or name

English

0 references

publication date

1 December 2016

1 reference

http://europepmc.org/abstract/PMC/5385895

22 June 2018

published in

Cell

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6 June 2020

volume

167

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6 June 2020

issue

6

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6 June 2020

page(s)

1540-1554.e12

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Fulminant Myocarditis with Combination Immune Checkpoint Blockade

6 June 2020

cites work

1 reference

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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

23 June 2018

1 reference

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Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

23 June 2018

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T Cell Factor 1-Expressing Memory-like CD8( ) T Cells Sustain the Immune Response to Chronic Viral Infections

23 June 2018

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Defining CD8 T cells that provide the proliferative burst after PD-1 therapy

23 June 2018

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Follicular CXCR5- expressing CD8( ) T cells curtail chronic viral infection

23 June 2018

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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

23 June 2018

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Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling

23 June 2018

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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

23 June 2018

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Molecular and cellular insights into T cell exhaustion

23 June 2018

1 reference

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Blockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infection

23 June 2018

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STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

23 June 2018

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Immune checkpoint blockade: a common denominator approach to cancer therapy

23 June 2018

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TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity

23 June 2018

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Overcoming T cell exhaustion in infection and cancer

23 June 2018

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

23 June 2018

1 reference

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

23 June 2018

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Molecular and genetic properties of tumors associated with local immune cytolytic activity

23 June 2018

1 reference

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

23 June 2018

1 reference

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

23 June 2018

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MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

23 June 2018

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23 June 2018

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23 June 2018

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New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape

23 June 2018

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23 June 2018

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Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8( ) T cells

23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape

23 June 2018

1 reference

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Type I interferon is selectively required by dendritic cells for immune rejection of tumors

23 June 2018

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23 June 2018

1 reference

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Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

23 June 2018

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23 June 2018

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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

23 June 2018

1 reference

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Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade

23 June 2018

1 reference

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A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model

23 June 2018

1 reference

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Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

23 June 2018

1 reference

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10.1016/J.CELL.2016.11.022

23 June 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27912061 AND SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27912061 AND SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

27912061

1 reference