Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression. (Q38674158)

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10 February 2020

title

Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression (English)

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10 February 2020

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1 reference

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7

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10 February 2020

Peter Davies

9

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10 February 2020

author name string

Xiyun Chai

1

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10 February 2020

Su Wu

2

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10 February 2020

Tracey K Murray

3

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10 February 2020

Robert Kinley

4

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10 February 2020

Claire V Cella

5

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10 February 2020

Helen Sims

6

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10 February 2020

Jenna Hanmer

8

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10 February 2020

Michael J O'Neill

10

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10 February 2020

Michael L Hutton

11

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10 February 2020

Martin Citron

12

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10 February 2020

language of work or name

English

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publication date

12 August 2011

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Journal of Biological Chemistry

10 February 2020

published in

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volume

286

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issue

39

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10 February 2020

page(s)

34457-34467

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Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

10 February 2020

cites work

1 reference

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Transmission and spreading of tauopathy in transgenic mouse brain

6 September 2017

1 reference

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Active and passive immunotherapy for neurodegenerative disorders

6 September 2017

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Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification

6 September 2017

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Tau protein, the paired helical filament and Alzheimer's disease

6 September 2017

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An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice

6 September 2017

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Tau suppression in a neurodegenerative mouse model improves memory function

6 September 2017

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

6 September 2017

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A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

6 September 2017

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Laboratory Investigation of Cerebrospinal Fluid Proteins

6 September 2017

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Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility

6 September 2017

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Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg.

6 September 2017

1 reference

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Propagation of tau misfolding from the outside to the inside of a cell.

14 September 2017

1 reference

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Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

14 September 2017

1 reference

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

14 September 2017

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

23 June 2018

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Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice

23 June 2018

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Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

31 August 2018

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Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies.

31 August 2018

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Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein

31 August 2018

1 reference

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Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

31 August 2018

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Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

31 August 2018

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cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease.

31 August 2018

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Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

31 August 2018

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Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

31 August 2018

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31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21841002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.229633

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841002 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841002 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

21841002

1 reference