Centrosomes in spindle organization and chromosome segregation: a mechanistic view (Q38661407)

5 September 2017

title

Centrosomes in spindle organization and chromosome segregation: a mechanistic view (English)

1 reference

5 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26643311 AND SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Patrick Meraldi

series ordinal

1

1 reference

5 September 2017

language of work or name

1 reference

7 December 2015

1 reference

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26643311 AND SRC:MED&resulttype=core&format=json

8 June 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26643311 AND SRC:MED&resulttype=core&format=json

8 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26643311 AND SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

19-34

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26643311 AND SRC:MED&resulttype=core&format=json

STIL microcephaly mutations interfere with APC/C-mediated degradation and cause centriole amplification

8 June 2020

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Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

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Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability

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Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I.

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Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.

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Centrioles Regulate Centrosome Size by Controlling the Rate of Cnn Incorporation into the PCM

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DNA breaks and chromosome pulverization from errors in mitosis

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The Kinesin-12 Kif15 is a processive track-switching tetramer

21 January 2018

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Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

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C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle.

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Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

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C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

21 January 2018

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A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

21 January 2018

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A mechanism linking extra centrosomes to chromosomal instability

21 January 2018

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Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregation

21 January 2018

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Genetic causes of microcephaly and lessons for neuronal development

21 January 2018

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Oncogene-like induction of cellular invasion from centrosome amplification

21 January 2018

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Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

21 January 2018

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Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos

21 January 2018

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Merotelic kinetochore attachment: causes and effects.

21 January 2018

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MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway

21 January 2018

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Synergy between multiple microtubule-generating pathways confers robustness to centrosome-driven mitotic spindle formation

21 January 2018

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Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

21 January 2018

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Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

Requirement of a centrosomal activity for cell cycle progression through G1 into S phase

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

Losing balance: the origin and impact of aneuploidy in cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Drosophila neuroblasts retain the daughter centrosome.

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

21 January 2018

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Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

21 January 2018

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21 January 2018

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The centrosome and cellular organization

21 January 2018

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Centrosome-independent mitotic spindle formation in vertebrates

21 January 2018

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Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

21 January 2018

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Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL.

21 January 2018

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Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

21 January 2018

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Aurora B is enriched at merotelic attachment sites, where it regulates MCAK.

21 January 2018

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Mode of centriole duplication and distribution

21 January 2018

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Mechanisms of spindle positioning: cortical force generators in the limelight

21 January 2018

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Spindle orientation and epidermal morphogenesis

21 January 2018

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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

21 January 2018

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Correcting improper chromosome-spindle attachments during cell division

21 January 2018

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A molecular marker for centriole maturation in the mammalian cell cycle

21 January 2018

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Mechanisms of intracellular scaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Molecular pathways regulating mitotic spindle orientation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

EGF-induced centrosome separation promotes mitotic progression and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Breaking the ties that bind: new advances in centrosome biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrosome amplification causes microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrosome dynamics as a source of chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Cyclin B2 and p53 control proper timing of centrosome separation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

WDR62 is associated with the spindle pole and is mutated in human microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

21 January 2018

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Mitotic spindle (DIS)orientation and DISease: cause or consequence?

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

21 January 2018

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https://api.crossref.org/works/10.1007/S10577-015-9508-2

The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Mitotic spindle misorientation in cancer – out of alignment and into the fire

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Chromosomal instability and aneuploidy in cancer: from yeast to man

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrosome-dependent exit of cytokinesis in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Robust control of mitotic spindle orientation in the developing epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Experiments concerning the cleavage stimulus in sand dollar eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Timing of centrosome separation is important for accurate chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Spindle orientation during asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

A primary microcephaly protein complex forms a ring around parental centrioles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Loss of centrioles causes chromosomal instability in vertebrate somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Biased segregation of DNA and centrosomes: moving together or drifting apart?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Kif15 cooperates with eg5 to promote bipolar spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Mechanisms of centrosome separation and bipolar spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

VHL loss causes spindle misorientation and chromosome instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

The role of Hklp2 in the stabilization and maintenance of spindle bipolarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Asymmetric inheritance of mother versus daughter centrosome in stem cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

The ciliary rootlet maintains long-term stability of sensory cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Chromothripsis from DNA damage in micronuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10577-015-9508-2

Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein

21 January 2018

1 reference

12 December 2020

The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts.

1 reference

12 December 2020

Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran

1 reference

12 December 2020

The Janus soul of centrosomes: a paradoxical role in disease?

1 reference

12 December 2020

Anaphase Spindle Mechanics Prevent Mis-Segregation of Merotelically Oriented Chromosomes

1 reference

12 December 2020

Influence of centriole number on mitotic spindle length and symmetry

1 reference

12 December 2020

1 reference

12 December 2020

The GTPase RAN regulates multiple steps of the centrosome life cycle.

1 reference

12 December 2020

Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran

1 reference

12 December 2020

Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues

1 reference

12 December 2020

Mitotic kinase cascades orchestrating timely disjunction and movement of centrosomes maintain chromosomal stability and prevent cancer

1 reference

12 December 2020

The equatorial position of the metaphase plate ensures symmetric cell divisions

1 reference

12 December 2020

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

12 December 2020

Centrosome defects and genetic instability in malignant tumors

1 reference

12 December 2020

Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size

1 reference

12 December 2020