Autophagy in stem and progenitor cells (Q38616599)

4 September 2017

title

Autophagy in stem and progenitor cells (English)

1 reference

4 September 2017

0 references

Carlo Rodolfo

1

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Francesco Cecconi

object named as

Francesco Cecconi

series ordinal

3

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author name string

Sabrina Di Bartolomeo

series ordinal

2

1 reference

4 September 2017

publication date

26 October 2015

1 reference

Cellular and Molecular Life Sciences

4 September 2017

published in

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4 September 2017

volume

73

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4 September 2017

issue

3

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4 September 2017

page(s)

475-496

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Regulation mechanisms and signaling pathways of autophagy

4 September 2017

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation

21 January 2018

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AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

21 January 2018

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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

21 January 2018

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Autophagy gene-dependent clearance of apoptotic cells during embryonic development

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Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models

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mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

21 January 2018

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

21 January 2018

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Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells

21 January 2018

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Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs

21 January 2018

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Receptor protein complexes are in control of autophagy

21 January 2018

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Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells

21 January 2018

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Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity

21 January 2018

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Mitochondria in stem cells

21 January 2018

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HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

21 January 2018

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The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells

21 January 2018

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Bioenergetic shifts during transitions between stem cell states (2013 Grover Conference series)

21 January 2018

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

21 January 2018

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Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function.

21 January 2018

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New cell lines from mouse epiblast share defining features with human embryonic stem cells

21 January 2018

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Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain

21 January 2018

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Essential role for Nix in autophagic maturation of erythroid cells

21 January 2018

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Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells

21 January 2018

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Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor-induced angiogenesis

21 January 2018

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The hematopoietic stem cell niche: low in oxygen but a nice place to be.

21 January 2018

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Autophagy is required for self-renewal and differentiation of adult human stem cells

21 January 2018

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FOXO3A directs a protective autophagy program in haematopoietic stem cells.

21 January 2018

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Developmental potential and dynamic behavior of hematopoietic stem cells.

21 January 2018

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Staying alive: metabolic adaptations to quiescence

21 January 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

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mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

21 January 2018

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Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system

21 January 2018

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Mitophagy in hematopoietic stem cells: the case for exploration

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Metabolic regulation of hematopoietic stem cells in the hypoxic niche

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

21 January 2018

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Autophagy regulates the cell cycle of murine HSPCs in a nutrient-dependent manner.

21 January 2018

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Manifestations and mechanisms of stem cell aging.

21 January 2018

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A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells

21 January 2018

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Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

21 January 2018

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FIP200, an essential component of mammalian autophagy is indispensible for fetal hematopoiesis

21 January 2018

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mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

21 January 2018

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

21 January 2018

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Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

21 January 2018

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A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

21 January 2018

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Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

21 January 2018

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FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

21 January 2018

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Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

21 January 2018

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Autophagy as a regulatory component of erythropoiesis

21 January 2018

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Autophagy driven by a master regulator of hematopoiesis

21 January 2018

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A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

21 January 2018

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TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

21 January 2018

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Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

21 January 2018

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The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

21 January 2018

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Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

21 January 2018

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mTORC1 is essential for leukemia propagation but not stem cell self-renewal

21 January 2018

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p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

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Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The adult rat hippocampus contains primordial neural stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

21 January 2018

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FoxO3 controls autophagy in skeletal muscle in vivo

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FoxO3 regulates neural stem cell homeostasis

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FIP200 is required for maintenance and differentiation of postnatal neural stem cells.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity

21 January 2018

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The renewal and differentiation of Isl1 cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway

21 January 2018

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A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

21 January 2018

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GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The elusive nature and function of mesenchymal stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

The origins of mesenchymal stromal cell heterogeneity

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Mesenchymal stromal cells: new directions.

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Activation of autophagy in mesenchymal stem cells provides tumor stromal support

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Hypoxia induces autophagy of bone marrow-derived mesenchymal stem cells via activation of ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Stromal cell-derived factor-1β mediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Glucocorticoid dose determines osteocyte cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The cancer stem cell: premises, promises and challenges

21 January 2018

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https://api.crossref.org/works/10.1007/S00018-015-2071-3

Cancer stem cells: impact, heterogeneity, and uncertainty

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy in cancer stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Hypoxia-inducible factors, stem cells, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival

21 January 2018

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What is the malignant nature of human ductal carcinoma in situ?

21 January 2018

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The roles of BECN1 and autophagy in cancer are context dependent

21 January 2018

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Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion

21 January 2018

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The Warburg effect in 2012.

21 January 2018

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Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

21 January 2018

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Metastasis: cancer cell's escape from oxidative stress.

21 January 2018

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Redox-based escape mechanism from death: the cancer lesson.

21 January 2018

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Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

21 January 2018

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21 January 2018

Autophagy and Metabolism

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Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis

21 January 2018

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Role of autophagy in cancer: management of metabolic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Systemic spread is an early step in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Reversal of aberrant cancer methylome and transcriptome upon direct reprogramming of lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Pancreatic cancers require autophagy for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Physiological cellular reprogramming and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Pulmonary artery sarcoma: another cause of sudden death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy positively regulates the CD44( ) CD24(-/low) breast cancer stem-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Generation of breast cancer stem cells through epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy can contribute to cell death when combining targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Disease modeling and cell based therapy with iPSC: future therapeutic option with fast and safe application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

“Phagocytic” Lysosomes in Chromatolytic Neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-015-2071-3

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

21 January 2018

1 reference

12 December 2020

Ambra1 regulates autophagy and development of the nervous system

1 reference

12 December 2020

Apoptotic and autophagic pathways with relevant small-molecule compounds, in cancer stem cells

1 reference

12 December 2020

Autophagy, Warburg, and Warburg reverse effects in human cancer

1 reference

12 December 2020

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells

1 reference

12 December 2020

Microenvironmental regulation of cancer stem cell phenotypes.

1 reference

12 December 2020

Autophagy regulates adipose mass and differentiation in mice

1 reference

12 December 2020

Autophagic vacuoles in human red cells

1 reference

12 December 2020

A novel Gfer-Drp1 link in preserving mitochondrial dynamics and function in pluripotent stem cells

1 reference

12 December 2020

Autophagy induction is a survival response against oxidative stress in bone marrow-derived mesenchymal stromal cells

1 reference

12 December 2020

Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice

1 reference

12 December 2020

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

1 reference

12 December 2020

Intrapleural doxycycline control of malignant pleural effusions

1 reference

12 December 2020

Targeting autophagy addiction in cancer

1 reference

12 December 2020

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

1 reference

12 December 2020

iPSCs from cancer cells: challenges and opportunities

1 reference

12 December 2020

Roles of SATB2 in site-specific stemness, autophagy and senescence of bone marrow mesenchymal stem cells

1 reference

12 December 2020

Inhibition of autophagy alleviates the senescent state of rat mesenchymal stem cells during long-term culture.

1 reference

12 December 2020

AMPK and autophagy in glucose/glycogen metabolism

1 reference

12 December 2020

10.1007/S00018-015-2071-3

Identifiers

DOI

1 reference

4 September 2017

1 reference