Phosphorylation of amyloid beta (Aβ) peptides - a trigger for formation of toxic aggregates in Alzheimer's disease. (Q38608487)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21869458 AND SRC:MED&resulttype=core&format=json

11 February 2020

title

Phosphorylation of amyloid beta (Aβ) peptides - a trigger for formation of toxic aggregates in Alzheimer's disease (English)

1 reference

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11 February 2020

0 references

1 reference

1

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11 February 2020

author name string

Jochen Walter

series ordinal

2

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11 February 2020

publication date

1 August 2011

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11 February 2020

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11 February 2020

volume

3

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11 February 2020

issue

8

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11 February 2020

page(s)

803-812

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Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis

11 February 2020

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Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

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Using a Drosophila model of Alzheimer's disease.

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The non-amyloidogenic pathway: structure and function of alpha-secretases

6 September 2017

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6 September 2017

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The Amyloid Hypothesis and the clearance and degradation of Alzheimer's beta-peptide.

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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25 September 2017

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25 September 2017

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23 June 2018

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N-terminal Heterogeneity of Parenchymal and Cerebrovascular Aβ Deposits

23 June 2018

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Isolation, Chemical Characterization, and Quantitation of Aβ 3-Pyroglutamyl Peptide from Neuritic Plaques and Vascular Amyloid Deposits

23 June 2018

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

23 June 2018

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Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

23 June 2018

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Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain

23 June 2018

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Induced release of cell surface protein kinase yields CK1- and CK2-like enzymes in tandem

23 June 2018

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

23 June 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

23 June 2018

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2011 Alzheimer's disease facts and figures

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Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

A physiological role for amyloid-beta protein:enhancement of learning and memory

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

The role of tau phosphorylation and cleavage in neuronal cell death

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Tuning the conformation properties of a peptide by glycosylation and phosphorylation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Phosphorylation of amyloid-beta at the serine 26 residue by human cdc2 kinase

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Irreversible dimerization/tetramerization and post-translational modifications inhibit proteolytic degradation of A beta peptides of Alzheimer's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184981

Molecular genetics of Alzheimer's disease

31 August 2018

1 reference

12 December 2020

Kinetic analysis of amyloid fibril formation

1 reference

12 December 2020

On the seeding and oligomerization of pGlu-amyloid peptides (in vitro)

1 reference

12 December 2020

Ecto-protein kinase activities in normal and transformed cells

1 reference

12 December 2020

Evidence for ecto-protein kinase activity that phosphorylates Kemptide in a cyclic AMP-dependent mode

1 reference

12 December 2020

Synthetic post-translationally modified human A beta peptide exhibits a markedly increased tendency to form beta-pleated sheets in vitro

1 reference

12 December 2020

Evidence for CKI and CKII at the cell surface

1 reference

12 December 2020

Isomerization and/or racemization at Asp23 of Abeta42 do not increase its aggregative ability, neurotoxicity, and radical productivity in vitro

1 reference

12 December 2020

Folding stability of amyloid-beta 40 monomer is an important determinant of the nucleation kinetics in fibrillization

1 reference

12 December 2020

Identifiers

DOI

10.18632/AGING.100362

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21869458 AND SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21869458 AND SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

21869458

1 reference