Hippocampal insulin resistance and cognitive dysfunction (Q38606226)

4 September 2017

title

Hippocampal insulin resistance and cognitive dysfunction (English)

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4 September 2017

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Geert Jan Biessels

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4 September 2017

Lawrence P Reagan

series ordinal

2

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4 September 2017

language of work or name

English

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publication date

14 October 2015

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Nature Reviews Neuroscience

4 September 2017

published in

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4 September 2017

volume

16

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4 September 2017

issue

11

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4 September 2017

page(s)

660-671

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Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

4 September 2017

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Intra CA1 insulin microinjection improves memory consolidation and retrieval

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A biochemical and functional characterization of diet-induced brain insulin resistance

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Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus

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Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone.

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High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice

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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers

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Adipokines mediate inflammation and insulin resistance

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Strain-specific differences in cell proliferation and differentiation in the dentate gyrus of C57BL/6N and C3H/HeN mice fed a high fat diet

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High-fat diet impairs hippocampal neurogenesis in male rats

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Effects of a Saturated Fat and High Cholesterol Diet on Memory and Hippocampal Morphology in the Middle-Aged Rat

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31 March 2020

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The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood-brain barrier integrity differ for diet-induced obese and diet-resistant rats

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Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet

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Impaired long-term potentiation in obese zucker rats: possible involvement of presynaptic mechanism.

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Impairment of long-term potentiation in the CA1, but not dentate gyrus, of the hippocampus in Obese Zucker rats: role of calcineurin and phosphorylated CaMKII.

31 March 2020

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Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study.

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Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity

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Preserved LTP and water maze learning in hyperglycaemic-hyperinsulinemic ZDF rats

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Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

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31 March 2020

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31 March 2020

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Awake intranasal insulin delivery modifies protein complexes and alters memory, anxiety, and olfactory behaviors

31 March 2020

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A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin

31 March 2020

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31 March 2020

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Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats

31 March 2020

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PPARγ agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets

31 March 2020

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31 March 2020

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DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

31 March 2020

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DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.

31 March 2020

1 reference

Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet

31 March 2020

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Deterioration of plasticity and metabolic homeostasis in the brain of the UCD-T2DM rat model of naturally occurring type-2 diabetes

31 March 2020

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Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice.

31 March 2020

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Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

31 March 2020

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Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice

31 March 2020

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Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor

31 March 2020

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Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons

31 March 2020

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Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy.

31 March 2020

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Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.

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Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes

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Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats

31 March 2020

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Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats

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31 March 2020

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The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

31 March 2020

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31 March 2020

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Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Rosiglitazone treatment reversed depression- but not psychosis-like behavior of db/db diabetic mice

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Identifiers

DOI

10.1038/NRN4019

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Dimensions Publication ID

4 September 2017

1031975454

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