Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis. (Q38554083)

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20 February 2020

review article

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title

Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis (English)

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20 February 2020

1

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20 February 2020

author name string

Andrew Aquilina

series ordinal

2

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20 February 2020

language of work or name

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26 July 2015

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Cellular and Molecular Life Sciences

20 February 2020

published in

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20 February 2020

volume

72

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20 February 2020

issue

21

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20 February 2020

page(s)

4127-4137

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Alpha B-crystallin in cardiac tissue. Association with actin and desmin filaments

20 February 2020

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AlphaB crystallin translocation and phosphorylation: signal transduction pathways and preconditioning in the isolated rat heart

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αB-crystallin, a small heat shock protein, modulates NF-κB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-α induced cytotoxicity

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Phosphorylation of Ser45 and Ser59 of αB‐crystallin and p38/extracellular regulated kinase activity determine αB‐crystallin‐mediated protection of rat brain astrocytes from C2‐ceramide‐ and staurosporine‐induced cell death

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The eye lens chaperone alpha-crystallin forms defined globular assemblies.

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Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin

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Alpha B-crystallin is a small heat shock protein

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Alpha-crystallin can function as a molecular chaperone

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Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

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Phosphorylations of αA- and αB-crystallin

21 January 2018

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The small heat shock protein alphaA-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis

21 January 2018

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alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis

21 January 2018

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Alpha B crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts

21 January 2018

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Hypertonic stress induces alpha B-crystallin expression

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NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins

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Alpha B crystallin and HSP28 are enhanced in the cerebral cortex of patients with Alzheimer's disease.

21 January 2018

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Systemic augmentation of alphaB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation.

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Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

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AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

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Phosphorylation of αB-Crystallin in Response to Various Types of Stress

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21 January 2018

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The possible role of α-crystallins in human senile cataractogenesis

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Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation

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Conversion from oligomers to tetramers enhances autophosphorylation by lens alpha A-crystallin. Specificity between alpha A- and alpha B-crystallin subunits

21 January 2018

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An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy

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21 January 2018

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Phosphorylation-induced change of the oligomerization state of alpha B-crystallin

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Ser-59 is the major phosphorylation site in alphaB-crystallin accumulated in the brains of patients with Alexander's disease

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Phosphorylation of α-crystallin B in Alexander's disease brain

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αB-Crystallin mutation in dilated cardiomyopathies: Low prevalence in a consecutive series of 200 unrelated probands

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Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer

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Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

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Innervation-dependent phosphorylation and accumulation of alphaB-crystallin and Hsp27 as insoluble complexes in disused muscle

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A novel mutation in CRYAA is associated with autosomal dominant suture cataracts in a Chinese family

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Ischemia-induced phosphorylation and translocation of stress protein αB-crystallin to Z lines of myocardium

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Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm

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Identification of crystallin modifications in the human lens cortex and nucleus using laser capture microdissection and CyDye labeling

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Overexpression and abnormal modification of the stress proteins alpha B-crystallin and HSP27 in Alexander disease

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Nonenzymatic phosphorylation of tyrosine and serine by ATP is catalyzed by manganese but not magnesium

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Structural and functional roles of deamidation of N146 and/or truncation of NH2- or COOH-termini in human αB-crystallin

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Binding of the stress protein alpha B-crystallin to cardiac myofibrils correlates with the degree of myocardial damage during ischemia/reperfusion in vivo

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12 December 2020

Modifications of the water-insoluble human lens alpha-crystallins

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An atypical form of alphaB-crystallin is present in high concentration in some human cataractous lenses. Identification and characterization of aberrant N- and C-terminal processing

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A novel fan-shaped cataract-microcornea syndrome caused by a mutation of CRYAA in an Indian family

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A nonsense mutation (W9X) in CRYAA causes autosomal recessive cataract in an inbred Jewish Persian family

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Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death

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Hierarchy of Lens Proteins Requiring Protection Against Heat-Induced Precipitation by the α Crystallin Chaperone

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The reaction of citraconic anhydride with bovine alpha-crystallin lysine residues. Surface probing and dissociation-reassociation studies

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Chaperone activity in the lens

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Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family

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αβ-crystallin interacts with intermediate filaments in response to stress

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alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner

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Existence of deamidated alphaB-crystallin fragments in normal and cataractous human lenses.

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Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses

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Alpha-crystallin/small heat shock protein has autokinase activity

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Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G

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Post-translational modifications of water-soluble human lens crystallins from young adults

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10.1007/S00018-015-1996-X

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26210153 AND SRC:MED&resulttype=core&format=json

20 February 2020

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